Do oestrogen receptors play a role in the pathogenesis of HIV-associated lipodystrophy?

AIDS

Volumn 19, Issue 5, 2005, Pages 531-533

  Barzon, Luisa ^a   Zamboni, Mauro ^b   Pacenti, Monia ^a   Milan, Gabriella ^a   Bosello, Ottavio ^b   Federspil, Giovanni ^a   Palù, Giorgio ^a   Vettor, Roberto ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; ESTROGEN RECEPTOR BETA; PROTEINASE INHIBITOR; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

ADIPOSE TISSUE; ADULT; ARTICLE; DOWN REGULATION; GENE EXPRESSION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV ASSOCIATED LIPODYSTROPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; MALE; PATHOGENESIS; PRIORITY JOURNAL; RISK ASSESSMENT; SUBCUTANEOUS TISSUE;

EID: 17144388269     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000162344.73804.a1     Document Type: Article

References (7)

1. Galli M, Veglia F, Angarano G, Santambrogio S, Meneghini E, Gritti F, et al. Gender differences in antiretroviral drug-related adipose tissue alterations. Women are at higher risk than men and develop particular lipodystrophy patterns. J Acquir Immune Defic Syndr 2003; 34:58-61.
2. Collazos J, Mayo J, Martinez E, Ibarra S. Association between sexual disturbances and sexual hormones with specific antiretroviral drugs. AIDS 2002; 16:1294-1295.
3. Pedersen SB, Bruun JM, Hube F, Kristensen K, Hauner H, Richelsen B. Demonstration of estrogen receptor subtypes α and β in human adipose tissue: influences of adipose cell differentiation and fat depot localization. Mol Cell Endocrinol 2001; 182:27-37.
4. Gougeon ML, Penicaud L, Fromenty B, Leclercq P, Viard JP, Capeau J. Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations. Antivir Ther 2004; 9:161-177.
5. Anderson LA, McTernan PG, Barnett AH, Kumar S. The effects of androgens and estrogens on preadipocyte proliferation in human adipose tissue: influence of gender and site. J Clin Endocrinol Metab 2001; 86:5045-5051.
6. Couse JF, Korach KS. Estrogen receptor null mice: what we have learned and where will they lead us? Endocr Rev 1999; 20:358-417.
7. Matthews J, Gustafsson J-A. Estrogen signaling: a subtle balance between ERα and ERβ. Mol Intervent 2003; 3:281-292.