Investigation of the relationships between logP and various chromatographic indices for a series of substituted coumarins. Evaluation of their similarity/dissimilarity using multivariate statistics

QSAR and Combinatorial Science

Volumn 24, Issue 2, 2005, Pages 254-260

  Vrakas, Demetris ^a   Panderi, Irene ^a   Hadjipavlou Litina, Dimitra ^b   Tsantili Kakoulidou, Anna ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Molecular descriptors; Multiple regression analysis; Multivariate data analysis; Octanol water partition coefficients; Reversed Phase Chromatography, Extrapolated capacity factors; Substituted Coumarins

Indexed keywords

DATA HANDLING; EXTRAPOLATION; INFORMATION ANALYSIS; MULTIVARIANT ANALYSIS; REGRESSION ANALYSIS; THIN LAYER CHROMATOGRAPHY;

CAPACITY FACTORS; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR DESCRIPTORS; MULTIPLE REGRESSION ANALYSIS; MULTIVARIATE DATA ANALYSIS; MULTIVARIATE STATISTICS; OCTANOL-WATER PARTITION COEFFICIENT; REVERSED PHASE CHROMATOGRAPHY; REVERSED-PHASE CHROMATOGRAPHY, EXTRAPOLATED CAPACITY FACTOR; SUBSTITUTED COUMARIN;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMIDOXIME DERIVATIVE; COUMARIN DERIVATIVE; HETEROCYCLIC COMPOUND; OCTANOL; OXIME DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ANALYTIC METHOD; ARTICLE; CALCULATION; CORRELATION ANALYSIS; DIPOLE; DRUG DETERMINATION; DRUG STRUCTURE; EVALUATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MULTIVARIATE ANALYSIS; PARAMETER; PARTITION COEFFICIENT; PRIORITY JOURNAL; REVERSED PHASE THIN LAYER CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; STRUCTURE ANALYSIS; TECHNIQUE; THIN LAYER CHROMATOGRAPHY;

EID: 17144377828     PISSN: 1611020X     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.200430898     Document Type: Article

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