Mortality during the first 24 months after delivery in relation to CD4 T-lymphocyte levels and viral load in a cohort of breast-feeding HIV-1-infected women in Dar es Salaam, Tanzania

Journal of Acquired Immune Deficiency Syndromes

Volumn 38, Issue 5, 2005, Pages 598-602

  Kilewo, Charles ^a   Karlsson, Katarina ^b   Swai, Andrew ^a   Massawe, Augustine ^a   Lyamuya, Eligius ^a   Mhalu, Fred ^a   Biberfeld, Gunnel ^b,c  

^a MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^b KAROLINSKA INSTITUTE   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Africa; HIV; Mortality; Survival; Women

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; LAMIVUDINE; ZIDOVUDINE;

ARTICLE; BREAST FEEDING; COHORT ANALYSIS; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MATERNAL MORTALITY; MORTALITY; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TANZANIA; VERTICAL TRANSMISSION; VIRUS LOAD;

ACQUIRED IMMUNODEFICIENCY SYNDROME; BREAST FEEDING; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; DELIVERY, OBSTETRIC; FEMALE; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; HUMANS; PATIENT DROPOUTS; PREGNANCY; TANZANIA; TIME FACTORS; VIRAL LOAD;

EID: 17144373730     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.qai.0000141483.33101.ef     Document Type: Article

References (15)

1. UNAIDS/WHO 2003. AIDS Epidemic Update 2003. Geneva. UNAIDS.
2. Nduati R, Richardson BA, John G, et al. Effect of breastfeeding on mortality among HIV-1 infected women. Lancet. 2001;357:1651-1655.
3. Coutsoudis A, Coovadia H, Pillay K, et al. Are HIV-infected women who breastfeed at increased risk of mortality? AIDS. 2001;15:653-655.
4. + lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med. 1997;126:946-954.
5. + T-cell count and function: markers with reciprocal predictive value over time after seroconversion. AIDS. 1997;11:1799-1806.
6. French N, Mujugira A, Nakiyingi J, et al. Immunologic and clinical stages in HIV-1-infected Ugandan adults are comparable and provide no evidence of rapid progression but poor survival with advanced disease. J Acquir Immune Defic Syndr. 1999;22:509-516.
7. Morgan D, Rutebemberwa A, Malamba S, et al. HIV-1 RNA levels in an African population-based cohort and their relation to CD4 lymphocyte counts and World Health Organization clinical staging. J Acquir Immune Defic Syndr. 1999;22:167-173.
8. The Petra team. Efficacy of three short-course regimen of Zidovudine and Lamivudine in preventing early and late transmission of HIV-1 from mother to child in Tanzania, South Africa and Uganda (Petra study): a randomized, double-blind, placebo-controlled trial. Lancet. 2002;359:1178-1186.
9. World Health Organization. Acquired immune deficiency syndrome (AIDS): interim proposal for a WHO staging system for HIV infection and disease. Wkly Epidemiol Rec. 1990;65:221-228.
10. Shafer N, Chuachoowong R, Mock PA, et al. Short course zidovudine for perinatal HIV transmission in Bangkok, Thailand: a randomised placebo-controlled trial. Lancet. 1999;353:773-780.
11. Urassa WK, Mbena EM, Swai AB, et al. Lymphocyte subset enumeration in HIV seronegative and HIV-1 seropositive adults in Dar es Salaam, Tanzania: determination of reference values in males and females and comparison of two flow cytometric methods. J Immunol Methods. 2003;277:65-74.
12. Lindan CP, Allen S, Serufilira A, et al. Predictors of mortality among HIV-infected women in Kigali, Rwanda. Ann Intern Med. 1992;116:320-328.
13. Leroy V, Msellati P, Lepage P, et al. Four years of natural history of HIV-1 infection in African women: a prospective cohort study in Kigali (Rwanda), 1988-1993. J Acquir Immune Defic Syndr Hum Retrovirol. 1995;9:415-421.
14. Morgan D, Mahe C, Mayanja B, et al. HIV-1 infection in rural Africa: is there a difference in median time to AIDS and survival compared with that in industrialized countries? AIDS. 2002;16:597-603.
15. World Health Organization. Scaling Up Antiretroviral Therapy in Resource-Limited Settings: Treatment Guidelines for a Public Health Approach: 2003 Revision. World Health Organization: 2004.