Amelioration of endothelin-1-induced optic nerve head ischemia by topical bunazosin

Current Eye Research

Volumn 30, Issue 2, 2005, Pages 81-91

  Goto, Wakana ^a   Oku, Hidehiro ^a   Okuno, Takashi ^a   Sugiyama, Tetsuya ^a   Ikeda, Tsunehiko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Bunazosin; Endothelin 1; Optic nerve head blood flow; Rabbit; Visually evoked potential

Indexed keywords

BUNAZOSIN; DRUG VEHICLE; ENDOTHELIN 1; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; CAPILLARY FLOW; CONTROLLED STUDY; DRUG EFFECT; DRUG INDUCED DISEASE; EVOKED VISUAL RESPONSE; EYE BLOOD FLOW; GLAUCOMA; INTRAOCULAR HYPOTENSION; ISCHEMIC OPTIC NEUROPATHY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RECEPTOR BLOCKING; VISION; VITREOUS BODY;

ADMINISTRATION, TOPICAL; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; BLOOD PRESSURE; ENDOTHELIN-1; EVOKED POTENTIALS, VISUAL; INJECTIONS; INTRAOCULAR PRESSURE; ISCHEMIA; OPTIC DISK; QUINAZOLINES; RABBITS; REGIONAL BLOOD FLOW; RETINA; VITREOUS BODY;

EID: 17144373362     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1080/02713680490904386     Document Type: Article

References (45)

1. Drance S. Chronic open angle glaucoma: Risk factors in addition to intraocular pressure. Acta Ophthalmol Scand. 2001;79:545.
2. Drance S, Anderson DR, Schulzer M. Risk factors for progression of visual field abnormalities in normal-tension glaucoma. Am J Ophthalmol. 2001;131:699-708.
3. Galassi F, Sodi A, Ucci F, Harris A, Chung HS. Ocular haemodynamics in glaucoma associated with high myopia. Int Ophthalmol. 1998;22:299-305.
4. Leske MC, Connell AM, Wu SY, Hyman LG, Schachat AP. Risk factors for open-angle glaucoma. The barbados eye study. Arch Ophthalmol. 1995;113:918-924.
5. Maruyama I, Nakazawa M, Ohguro H. [Autoimmune mechanisms in molecular pathology of glaucomatous optic neuropathy]. J Jpn Ophthalmic Soc. 2001;105:205-212.
6. Orgul S, Gass A, Flammer J. Optic disc cupping in arteritic anterior ischemic optic neuropathy. Ophthalmologica. 1994;208:336-338.
7. Broadway DC, Drance SM. Glaucoma and vasospasm. Br J Ophthalmol. 1998;82:862-870.
8. Haefliger IO, Dettmann E, Liu R, Meyer P, Prunte C, Messerli J, Flammer J. Potential role of nitric oxide and endothelin in thepathogenesis of glaucoma. Surv Ophthalmol. 1999;43:551-58.
9. Van Buskirk EM, Cioffi GA. Glaucomatous optic neuropathy. Am J Ophthalmol. 1992;113:447-452.
10. La M, Reid JJ. Endothelin-1 and the regulation of vascular tone. Clin Exp Pharmacol Physiol. 1995;22:315-323.
11. MacCumber MW, Jampel HD, Snyder SH. Ocular effects of the endothelins. Abundant peptides in the eye. Arch Ophthalmol. 1991;109:705-709.
12. Murata M, Nakagawa M, Takahashi S. Selective expression of endothelin 1 mRNA in rat retina. Ophthalmologica. 1998;212:331-333.
13. Yorio T, Krishnamoorthy R, Prasanna G. Endothelin: Is it a contributor to glaucoma pathophysiology? J Glaucoma. 2002;11:259-270.
14. Noske W, Hensen J, Wiederholt M. Endothelin-like immunoreactivity in aqueous humor of patients with primary open-angle glaucoma and cataract. Graefes Arch Clin Exp Ophthalmol. 1997;235:551-552.
15. Cellini M, Possati GL, Profazio V, Sbrocca M, Caramazza N, Caramazza R. Color Doppler imaging and plasma levels of endothelin-1 in low-tension glaucoma. Acta Ophthalmol Scand Suppl. 1997;224:11-13.
16. Sugiyama T, Moriya S, Oku H, Azuma I. Association of endothelin-1 with normal tension glaucoma: Clinical and fundamental studies. Surv Ophthalmol. 1995;39:S49-56.
17. Orgül S, Cioffi GA, Wilson DJ, Bacon DR, Van Buskirk EM. An endothelin-1 induced model of optic nerve ischemia in the rabbit. Invest Ophthalmol Vis Sci. 1996;37:1860-1869.
18. Oku H, Sugiyama T, Kojima S, Watanabe T, Azuma I. Experimental optic cup enlargement caused by endothelin-1-induced chronic optic nerve head ischemia. Surv Ophthalmol. 1999;44:S74-S84.
19. Kaburagi S, Hasegawa K, Morimoto T, Araki M, Sawamura T, Masaki T, Sasayama S. The role of endothelin-converting enzyme-1 in the development of alpha1-adrenergic-stimulated hypertrophy in cultured neonatal rat cardiac myocytes. Circulation. 1999;99:292-298.
20. Matsuda H, Kawaguchi A, Uematsu M, Ohmori F, Nagata S, Miyatake K. Endothelins contract guinea-pig pulmonary artery and enhance its adrenergic response via ET(A) receptors. Clin Exp Pharmacol Physiol. 1996;23:379-385.
21. Todorov S, Petkov O, Nikolov R, Zamfirova R. Involvement of Ca2+ and alpha 1-adrenoceptors in endothelin-1 effects on the tone and electrically evoked contractions of rabbit ear central artery. Methods Find Exp Clin Pharmacol. 1995;17:391-395.
22. Sugiyama T, Oku H, Moriya S, Shimizu K, Azuma I. [Evaluation of bunazosin hydrochloride with a model of ocular circulation disturbance induced by endothelin-1]. J Jpn Ophthalmic Soc. 1994;98:63-68.
23. Oku H, Sugiyama T, Kojima S, Watanabe T, Ikeda T. Improving effects of topical administration of iganidipine, a new calcium channel blocker, on the impaired visual evoked potential after endothelin-1 injection into the vitreous body of rabbits. Curr Eye Res. 2000;20:101-108.
24. Tamaki Y, Araie M, Kawamoto E, Eguchi S, Fujii H. Non-contact, two-dimensional measurement of tissue circulation in choroid and optic nerve head using laser speckle phenomenon. Exp Eye Res. 1995;60:373-383.
25. Sugiyama T, Utsumi T, Azuma I, Fujii H. Measurement of optic nerve head circulation: Comparison of laser speckle and hydrogen clearance methods. Jpn J Ophthalmol. 1996;40:339-343.
26. Okuno T, Oku H, Ikeda T. The reproducibility and sensitivity of visual evoked potential testing in rabbits. Neuro-Ophthalmol. 2002;26:59-66.
27. Thompson J, Woolsey C, Talbot S. Visual areas and cerebral cortex of rabbit. J Neurophysiol. 1950;13:278-288.
28. Hughes A, Wilson ME. Callosal terminations along the boundary between visual areas I and II in the rabbit. Brain Res. 1969;12:19-25.
29. Kuwahara M, Yagi Y, Birumachi J, Sekizawa S, Tsubone H, Sugano S, Kobayashi H. Non-invasive measurement of systemic arterial pressure in guinea pigs by an automatic oscillometric device. Blood Press Monit. 1996;1:433-437.
30. Kida T, Oku H, Sugiyama T, Ikeda T. The mechanism and change in the optic nerve head (ONH) circulation in rabbits after glucose loading. Curr Eye Res. 2001;22:95-101.
31. Frishman U, Shen FF, Du L, Robson JG, Harwerth RS, Smith EL 3rd, Carter-Dawson L, Crawford ML. The scotopic electroretinogram of macaque after retinal ganglion cell loss from experimental glaucoma. Invest Ophthalmol Vis Sci. 1996;37:125-141.
32. Sugiyama K, Bacon DR, Morrison JC, Van Buskirk EM. Optic nerve head microvasculature of the rabbit eye. Invest Ophthalmol Vis Sci. 1992;33:2251-2261.
33. Granstam E, Wang L, Bill A. Ocular effects of endothelin-1 in the cat. Curr Eye Res. 1992;11:325-332.
34. Riva CE, Hero M, Titze P, Petrig B. Autoregulation of human optic nerve head blood flow in response to acute changes in ocular perfusion pressure. Graefes Arch Clin Exp Ophthalmol. 1997;235:618-626.
35. Oku H, Sugiyama T, Moriya S, Hamada J, Azuma I. [Effects of intravitreal injection of endothelin on the visual system]. J Jpn Ophthalmic Soc. 1993;97:467-473.
36. Ciulla TA, Pawlyk BS, Harris A, Oberoi A, Miller JW, Sandberg MA. Endothelin-1-mediated retinal artery vasospasm and the rabbit electroretinogram. J Ocul Pharmacol Ther. 2000;16:393-398.
37. Ohkubo H, Chiba S. Pharmacological analysis of vasoconstriction of isolated canine ophthalmic and ciliary arteries to alpha-adrenoceptor agonists. Exp Eye Res. 1987;45:263-270.
38. Forster BA, Ferrari-Dileo G, Anderson DR. Adrenergic alpha 1 and alpha 2 binding sites are present in bovine retinal blood vessels. Invest Ophthalmol Vis Sci. 1987;28:1741-1746.
39. Goto W, Ota T, Morikawa N, Otori Y, Hara H, Kawazu K, Miyawaki N, Tano Y. Protective effects of timolol against the neuronal damage induced by glutamate and ischemia in the rat retina. Brain Res. 2002;958:10-19.
40. Mizuno K, Koide T, Saito N, Fujii M, Nagahara M, Tomidokoro A, Tamaki Y, Araie M. Topical nipradilol: Effects on optic nerve head circulation in humans and periocular distribution in monkeys. Invest Ophthalmol Vis Sci. 2002;43:3243-3250.
41. Hayashi-Morimoto R, Yoshitomi T, Ishikawa H, Hayashi E, Sato Y. Effects of beta antagonists on mechanical properties in rabbit ciliary artery. Graefes Arch Clin Exp Ophthalmol. 1999;237:661-667.
42. Kotake H, Noguchi N, Matsuoka S, Hisatome I, Hasegawa J, Mashiba H. Bunazosin, an alpha-adrenoceptor antagonist, blocks calcium current in guinea-pig ventricular myocytes. Comp Biochem Physiol C. 1991;100:401-404.
43. Prasanna G, Krishnamoorthy R, Clark AF, Wordinger RJ, Yorio T. Human optic nerve head astrocytes as a target for endothelin-1. Invest Ophthalmol Vis Sci. 2002;43:2704-2713.
44. Stokely ME, Brady ST, Yorio T. Effects of endothelin-1 on components of anterograde axonal transport in optic nerve. Invest Ophthalmol Vis Sci. 2002;43:3223-3230.
45. Ichikawa M, Okada Y, Asai Y, Hara H, Ishii K, Araie M. Effects of topically instilled bunazosin, an alphal-adrenoceptor antagonist, on constrictions induced by phenylephrine and ET-1 in rabbit retinal arteries. Invest Ophthalmol Vis Sci. 2004;45:4041-4048.