Heterogeneity in the binding of lipid molecules to the surface of a membrane protein: Hot spots for anionic lipids on the mechanosensitive channel of large conductance MscL and effects on conformation

Biochemistry

Volumn 44, Issue 15, 2005, Pages 5873-5883

  Powl, Andrew M ^a   East, J Malcolm ^a   Lee, Anthony G ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; FLUORESCENCE; MUTAGENESIS; NEGATIVE IONS; PROTEINS; QUENCHING; SPECTRUM ANALYSIS;

ANIONIC PHOSPHOLIPIDS; HETEROGENEITY; LIPID MOLECULES; MECHANOSENSITIVE CHANNEL;

PHOSPHOLIPIDS;

AMPHOLYTE; ANION; ARGININE; DIOLEOYLPHOSPHATIDIC ACID; DIOLEOYLPHOSPHATIDYLCHOLINE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; LYSINE; MEMBRANE PROTEIN; PHOSPHATIDIC ACID; PHOSPHOLIPID; TRYPTOPHAN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CYTOPLASM; GENE MUTATION; MECHANOSENSITIVE CHANNEL OF LARGE CONDUCTANCE; MEMBRANE CHANNEL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BINDING SITES; ELECTROCHEMISTRY; ION CHANNELS; KINETICS; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE LIPIDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE;

MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 17144372582     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047439e     Document Type: Article

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