Platelet activation can occur by shear stress alone in the PFA-100 platelet analyser

Platelets

Volumn 16, Issue 2, 2005, Pages 81-84

  Dunkley, Scott ^a   Harrison, Paul ^b  

^a PRINCE OF WALES HOSPITAL   (Australia)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENALIN; COLLAGEN; GLYCOPROTEIN IB ALPHA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY PAC 1; PADGEM PROTEIN; UNCLASSIFIED DRUG;

ANALYZER; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; LEUKOCYTE AGGREGATION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR RATE; SHEAR STRESS; SIMULATION; THROMBOCYTE ACTIVATION; THROMBOCYTE FUNCTION;

BLOOD PLATELETS; FEMALE; HUMANS; MALE; P-SELECTIN; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; RECEPTORS, CELL SURFACE; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; STRESS, MECHANICAL;

EID: 17144364597     PISSN: 09537104     EISSN: None     Source Type: Journal    
DOI: 10.1080/09537100400010352     Document Type: Article

References (13)

1. Brown CH, Leverett LB, Lewis CW, Alfrey CP, Heliums JD. Morphological, biochemical and functional changes in human platelets subjected to shear stress. J Lab Clin Med 1975;86:462-468.
2. Kroll MH, Hellums JD, McIntire LV, Schafer AI, Moake JL. Platelets and shear stress. Blood 1996;88:1525-1541.
3. Hu H, Varon D, Hjemdahl P, Savion N, Schulman S, Li N. Platelet-leukocyte aggregation under shear stress: differential involvement of selectins and integrins. Thromb Haemost 2003;90:679-687.
4. Harrison P. Progress in the assessment of platelet function. Br J Haematol 2000;111:733-744.
5. Shattil SJ, Cunningham M, Hoxie JA. Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry. Blood 1987;70:307-315.
6. Joseph JE, Harrison P, Mackie IJ, Isenberg DA, Machin SJ. Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis. Br J Haematol 2001;115:451-459.
7. Kundu SK, Heilman EJ, Sio R, Garcia C, Davidson RM, Ostgaard RA. Description of an in vitro platelet function analyser - PFA-100. Semin Thromb Hemost 1995;21(Suppl 2):106-112.
8. Rinder HM, Bonan JL, Rinder CS, Ault KA, Smith BA. Dynamics of leukocyte-platelet adhesion in whole blood. Blood 1991;78:1730-1737.
9. Hamburger SA, McEver RP. GMP-140 mediates adhesion of stimulated platelets to neutrophils. Blood 1990;75:550-554.
10. McEver RP. Leukocyte interactions mediated by selectins. Thromb Haemost 1990;66:80-87.
11. Michelson AD, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation 2001;104:1533-1537.
12. Wurzinger LJ, Pitz R, Blasberg P, Schmid-Schonbein H. Platelets and coagulation parameters following millisecond exposure to laminar shear stress. Thromb Haemost 1985;54:381-388.
13. Poujol C, Nurden A, Paponneau A, Heilmann E, Nurden P. Ultrastructural analysis of the distribution of von Willebrand factor and fibrinogen in platelet aggregates formed in the PFA-100. Platelets 1998;9:381-389.