Structural basis for selectivity of butyrylcholinesterase towards enantiomeric quinuclidin-3-yl benzoates: A quantum chemical study

Croatica Chemica Acta

Volumn 76, Issue 1, 2003, Pages 93-99

  Primožič, Ines ^a   Hrenar, Tomica ^a   Tomic S ^a   Meić, Zlatko ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

(R) and (S) quinuclidin 3 yl benzoates; Benzoylcholine; Butyrylcholinesterase; Mechanism of hydrolysis; Michaelis complexes; Semiempirical calculations; Tetrahedral intermediates

Indexed keywords

AMINO ACID; BENZOIC ACID; BENZOYLCHOLINE; CHOLINESTERASE; HYDROGEN; NITROGEN; PROTON; QUINUCLIDINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; CALCULATION; CATALYSIS; CHEMICAL ANALYSIS; ENANTIOMER; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HYDROGEN BOND; HYDROLYSIS; QUANTUM CHEMISTRY; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 17044457879     PISSN: 00111643     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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