DNA damage and repair in human lymphocytes and gastric mucosa cells exposed to chromium and curcumin

Teratogenesis Carcinogenesis and Mutagenesis

Volumn 19, Issue 1, 1999, Pages 19-31

  Błasiak, Janusz ^a   Trzeciak, Andrzej ^a   Małecka Panas, Ewa ^b   Drzewoski, Józef ^b   Iwanienko, Teresa ^c   Szumiel, Irena ^c   Wojewódzka, Maria ^c  

^a UNIVERSITY OF LODZ   (Poland)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

^c INSTITUTE OF NUCLEAR CHEMISTRY AND TECHNOLOGY   (Poland)

Author keywords

Carcinogen anticarcinogen interaction; Combined action of chemicals; Comet assay; DNA strand breaks; Single cell gel electrophoresis

Indexed keywords

ANTIOXIDANT; CHROMIUM; CURCUMIN; DNA;

ARTICLE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DOSE RESPONSE; DRUG POTENTIATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; INCUBATION TIME; LYMPHOCYTE; PRIORITY JOURNAL; STOMACH MUCOSA;

CELLS, CULTURED; CHROMIUM; CURCUMIN; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTRIC MUCOSA; HUMANS; LYMPHOCYTES; MODELS, CHEMICAL; MUTAGENICITY TESTS; TIME FACTORS;

EID: 17044451503     PISSN: 02703211     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6866(1999)19:1<19::AID-TCM3>3.0.CO;2-H     Document Type: Article

References (46)

1. IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Chromium, nickel and welding. IARC 1990;49:447-525.
2. Cohen MD, Kargacin B, Klein CB, Costa M. Mechanisms of chromium carcinogenicity and toxicity. Crit Rev Toxicol 1993;23:255-281.
3. Susa N, Ueno S, Furukawa Y, Ueda J, Sugiyama M. Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes. Toxicol Appl Pharmacol 1997;144:377-384.
4. Coogan TP, Mots J, Snyder CA, Squibb KS, Costa M. Differential DNA-protein crosslinking in lymphocytes and liver following chronic drinking water exposure of rat to potassium chromate. Toxicol Appl Pharmacol 1991;109:60-72.
5. De Flora S, Wetterhahn KE. Mechanism of chromium (VI) metabolism and genotoxicity. Life Chem Rep 1989;7:169-244.
6. Sugiyama M. Role of cellular antioxidants in metal-induced damage. Cell Biol Toxicol 1994;10:1-22.
7. Ueno S, Sugiyama M, Susa N, Furukawa Y. Effect of dimethylthiourea on chromium (VI)-induced DNA single-strand breaks in Chinese hamster V-79 cells. Mutat Res 1995;346:23-31.
8. Werfel U, Langen VI, Eickhoff I, Schoonbrood J, Vahrenholz C, Brauksiepe A, Popp W, Norpoth K. Elevated DNA single-strand breakage frequencies in lymphocytes of welders exposed to chromium and nickel. Carcinogenesis 1998;19:413-418.
9. Chopra RN, Chopra IC, Handa KI, Kapur LD. Indigenous Drugs of India. Calcutta: Dhur, 1958;325-327.
10. Sharma OP. Antioxidant of curcumin and related compounds. Biochem Pharmacol 1976;25:1811-1812.
11. Rao CV, Rivenson A, Simi B, Reddy BS. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res 1995;55:259-266.
12. Hanif R, Qiao L, Sfiff SJ, Rigas B. Curcumin, a natural plant phenolic food additive, inhibits cell proliferation and induces cell cycle changes in colon adenocarcinoma cell lines by a prostaglandin-independent pathway. J Lab Clin Med 1997;130:576-584.
13. Nagabhushan M, Bhide SV. Curcumin as an inhibitor of cancer. J Am Coll Nutr 1992;11:192-198.
14. Lu YP, Chang RL, Lou Y, Huang MT, Newmark HL, Reuhl KR, Conney AH. Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in the mouse epiderms. Carcinogenesis 1994;15:2263-2370.
15. Kakar SS, Roy D. Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc protooncogene messenger RNAs in mouse skin. Cancer Lett 1994;87:85-89.
16. Huang TZ, Lee SC, Lin JK. Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells. Proc Natl Acad Sci USA 1991;88:5292-5296.
17. Subramanian M, Sreejayan M, Rao MNA, Devasagayam TPA, Singh BB. Diminution of singlet oxygen-induced DNA damage by curcumin and related antioxidants. Mutat Res 1994;311:249-255.
18. Bagchi D, Vuchetich PJ, Bagchi M, Hassoun EA, Tran MX, Tang L, Stohs SJ. Induction of oxidative stress by chronic administration of sodium dichromate (chromium VI) and cadmium chloride (cadmium II) to rats. Free Radic Biol Med 1997;22:471-478.
19. Lloyd DR, Phillips DH, Carmichael PL. Generation of putative intrastrand cross-links and strand breaks in DNA by transition metal ion-mediated oxygen radical attack. Chem Res Toxicol 1997;10:393-400.
20. Xu J, Bubley GJ, Detrick B, Blankenship LJ, Patierno SR. Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle. Carcinogenesis 1996;17:1511-1517.
21. Sikora E, Bielak-Zmijewska A, Piwocka K, Skierski J, Radziszewska E. Inhibition of proliferation and apoptosis of human and rat T lymphocytes by curcumin, a curry pigment. Biochem Pharmacol 1997;54:899-907.
22. Donatus IA, Sardjoko, Vermeulen NPE. Cytotoxic and cytoprotective activities of curcumin. Effects of paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes. Biochem Pharmacol 1990;39:1869-1875.
23. Sahu SC, Washington MC. Effect of ascorbic acid and curcumin on quercitin-induced nuclear DNA damage, lipid peroxidation and protein degradation. Cancer Lett 1992;63:237-241.
24. Eastman A, Barry MA. The origins of DNA breaks: A consequence of DNA damage, DNA repair or apoptosis. Cancer Invest 1992;10:229-240.
25. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantification of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184-191.
26. McKelvey-Martin VJ, Green MHL, Schmezer P, Pool-Zobel BL, De Meo MP, Collins A. The single cell gel electrophoresis assay (comet assay): a European review. Mutat Res 1993;288:47-63.
27. Fairbairn DW, Olive PL, O'Neill KL. The comet assay: a comprehensive review. Mutat Res 1995;339:37-59.
28. Pool-Zobel BL, Lotzman N, Knoll M, Kuchenmeister F, Lambertz R, Leucht U, Schroder H-G, Schmezer P. Detection of genotoxic effects in human gastric and nasal mucosa cells isolated from biopsy samples. Environ Molec Mutagen 1994;24:23-45.
29. Hunt SV. Preparation of lymphocytes and accessory cells. In Klaus GGB, editor. Lymphocytes. A Practical Approach. Oxford: IRL Press; 1987. p 1-34.
30. Ashby JA, Tinwell H, Lefevre PA, Browne MA. The single cell gel electrophoresis assay for induced DNA damage (comet assay): measurement of tail length and moment. Mutagenesis 1995;10:85-90.
31. Tice RR, Andrews PW, Singh NP. The single cell gel assay: a sensitive technique for evaluating intercellular differences in DNA damage and repair. Basic Life Sci 1990;53:291-301.
32. Olive PL, Banath JP, Durand RE. Detection of etopside resistance by measuring DNA damage in individual Chinese hamster cells. J Natl Cancer Inst 1990;82:779-783.
33. Betti C, Barale R, Pool-Zobel BL. Comparative studies on cytotoxic and genotoxic effects of two organic mercury compounds in lymphocytes and gastric mucosa cells of Sprague-Dawley rats. Environ Mol Mutagen 1993;22:172-180.
34. Green MHL, Lowe JE, Harcourt SA, Akinluyi P, Rowe T, Cole J, Anstey AV, Arlett CF. UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: a potential diagnostic technique. Mutat Res 1992;273:137-144.
35. Speit G, Hartmann A. The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay). Mutagenesis 1995;10:555-559.
36. Hartmann A, Speit G. Genotoxic effects of the chemicals in the single gel cells in relation to the induction of sister chromatid exchange (SCE). Mutat Res 1995;346:49-56.
37. Occupational Exposure Limits. London HMSO. EH 40/93 Health and Safety Executive. 1993.
38. Gao M, Levy LS, Faux SP, Aw TC, Braithwaite RA, Brown SS. Use of molecular epidemiological techniques in a pilot study on workers exposed to chromium. Occup Environ Med 1994;51:663-668.
39. McAughey JJ, Samuel AM, Baxter PJ, Smith NJ. Biological monitoring of occupational exposure in the chromate pigment production industry. Sci Total Environ 1998;71:317-322.
40. Mehta RG, Moon RC. Characterization of effective chemopreventive agents in mammary glands in vitro using an initiation-promotion protocol. Anticancer Res 1991;11:593-596.
41. Rao CV, Simi B, Reddy BS. Inhibitory effect of dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon. Carcinogenesis 1993;14:2219-2225.
42. Makundan MA, Chacko MC, Annapurna VV, Krishnaswamy K. Effect of turmeric and curcumin on BP-DNA adducts. Carcinogenesis 1993;14:4493-4496.
43. Lahiri M, Marcu GB, Amonkar AJ, Bhide SV. Modulation of benzo(α)pyrene induced DNA damage by some chemopreventive agents. In: Bhide SV, Maru GB, editors. Chemoprevention of Cancer. New Delhi: Omega Scientific Publishers. 1992. p 152-161.
44. Stoner GD, Mukhtar H. Polyphenols as cancer chemopreventive agents. J Cell Biochem 1995;22:169-180.
45. Jiang MC, Yang-Yen HF, Yen JJ, Lin JK. Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines. Nutr Cancer 1996;26:111-120.
46. Uzawa A, Suzuki G, Nakata Y, Akashi M, Ohyama H, Akanuma A. Radiosensitivity of CD45RO+ memory and CD45RO-native T cells in culture. Radiat Res 1994;137:25-33.