Modulation of ventral pallidal dopamine and glutamate release by the intravenous anesthetic propofol studied by in vivo microdialysis

Amino Acids

Volumn 28, Issue 2, 2005, Pages 145-148

  Grasshoff, C ^a   Herrera Marschitz, M ^b,c   Goiny, M ^b   Kretschmer, B D ^a,d  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF CHILE   (Chile)

^d Department of Neuropharmacology ^*  (Germany)

Author keywords

Bicuculline; Dopamine; Glutamate; Propofol; Ventral pallidum

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ANESTHETIC AGENT; BICUCULLINE; GLUTAMIC ACID; PROPOFOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BRAIN REGION; CONFERENCE PAPER; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG EFFECT; DRUG MECHANISM; GABAERGIC SYSTEM; GLOBUS PALLIDUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MALE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; TISSUE LEVEL; VENTRAL TEGMENTUM;

ANESTHETICS, INTRAVENOUS; ANIMALS; BEHAVIOR, ANIMAL; BICUCULLINE; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIALYSIS; DOPAMINE; GABA ANTAGONISTS; GLUTAMIC ACID; HALLUCINATIONS; MALE; NEURONS; PROPOFOL; RATS; RATS, SPRAGUE-DAWLEY; SEXUAL DYSFUNCTIONS, PSYCHOLOGICAL; TELENCEPHALON;

EID: 17044426796     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-005-0160-6     Document Type: Conference Paper

References (25)

1. Bardo MT (1998) Neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens. Crit Rev Neurobiol 12: 37-67
2. Borgeat A, Wilder-Smith OH, Suter PM (1994) The nonhypnotic therapeutic applications of propofol. Anesthesiology 80: 642-656
3. Brazzalotto I (1989) Effects of propofol. Ann Fr Anesth Reanim 8: 388
4. Briker SRW (1988) Hallucinations after propofol. Anaesthesia 43: 171-171
5. Chebib M, Johnston GA (1999) The 'ABC' of GABA receptors: a brief review. Clin Exp Pharmacol Physiol 26: 937-940
6. Franks NP, Lieb WR (1994) Molecular and cellular mechanisms of general anaesthesia. Nature 367: 607-614
7. Gong W, Neill DB, Justice JB (1998) GABAergic modulation of ventral pallidal dopamine release studied by in vivo microdialysis in the freely moving rat. Synapse 29: 406-412
8. Hales TG, Lambert JJ (1991) The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurons. Br J Pharmacol 104: 619-628
9. Hara M, Kai Y, Ikemoto Y (1993) Propofol activates GABAA receptor-chloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat. Anesthesiology 79: 781-788
10. Hara M, Kai Y, Ikemoto Y (1994) Enhancement by propofol of the gamma-aminobutyric acidA response in dissociated hippocampal pyramidal neurons of the rat. Anesthesiology 81: 988-994
11. Hunter DN, Thornily A, Whitburn R (1987) Arousal from propofol. Anaesthesia 42: 1128-1129
12. Klitenick MA, Deutch AY, Churchill L, Kalivas PW (1992) Topography and functional role of dopaminergic projections from the ventral mesencephalic tegmentum to the ventral pallidum. Neuroscience 50: 371-386
13. Kretschmer BD (2000a) NMDA receptor antagonist-induced dopamine release in the ventral pallidum does not correlate with motor activation. Brain Res 859: 147-156
14. Kretschmer BD (2000b) Functional aspects of the ventral pallidum. Amino Acids 19: 201-210
15. Kretschmer BD, Goiny M, Herrera-Marschitz M (2000) Effect of intracerebral administration of NMDA and AMPA on dopamine and glutamate release in the ventral pallidum and on motor behavior. J Neurochem 74: 2049-2057
16. McBride WJ, Murphy JM, Ikemoto S (1999) Localization of brain reinforcement mechanisms: intracranial self-administration and intracranial place-conditioning studies. Behav Brain Res 101: 129-152
17. Pain L, Oberling P, Sandner G, Di Scala G (1996) Effect of propofol on affective state as assessed by place conditioning paradigm in rats. Anesthesiology 85: 121-128
18. Panagis G, Spyraki C (1996) Neuropharmacological evidence for the role of dopamine in ventral pallidum self-stimulation. Psychopharmacology Berl 123: 280-288
19. Peduto VA, Concas A, Santoro G, Biggio G, Gessa GL (1991) Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain. Anesthesiology 75: 1000-1009
20. Schwieler L, Delbro DS, Engberg D, Erhardt S (2003) The anaesthetic agent propofol interacts with GABAB-receptors: an electrophysiological study in rat. Life Sci 72: 2793-2801
21. Sneyd JR (1994) Propofol at a subanesthetic dose may have abuse potential in healthy volunteers [letter; comment]. Anesth Analg 78: 1032-1033
22. Whitehead C, Sanders LD, Oldroyd G, Haynes TK, Marshall RW, Rosen M, Robinson JO (1994) The subjective effects of low-dose propofol. A double-blind study to evaluate dimensions of sedation and consciousness with low-dose propofol. Anaesthesia 49: 490-496
23. Wisden W, Stephens DN (1999) Towards better benzodiazepines [news]. Nature 401: 751-752
24. Zacny JP, Lichtor JL, Coalson DW, Finn RS, Uitvlugt AM, Glosten B, Flemming DC, Apfelbaum JL (1992) Subjective and psychomotor effects of subanesthetic doses of propofol in healthy volunteers. Anesthesiology 76: 696-702
25. Zacny JP, Lichtor JL, Zaragoza JG, Coalson DW, Uitvlugt AM, Flemming DC, Binstock WB, Cutter T, Apfelbaum JL (1993) Assessing the behavioral effects and abuse potential of propofol bolus injections in healthy volunteers. Drug Alcohol Depend 32: 45-57