Hyperpolarization of 13C through order transfer from parahydrogen: A new contrast agent for MRI

Magnetic Resonance Imaging

Volumn 23, Issue 2 SPEC. ISS., 2005, Pages 153-157

  Goldman, Maurice ^a,b   Jóhannesson, Haukur ^a   Axelsson, Oskar ^a   Karlsson, Magnus ^a  

^a GE Healthcare Bio Sciences AB   (Sweden)

^b NONE   (France)

Author keywords

Adiabatic; Contrast agents; Field cycling; MRI; Parahydrogen induced polarization

Indexed keywords

CARBON 13; CONTRAST MEDIUM; HYDROGEN; PROTON; CARBON;

CONFERENCE PAPER; HYDROGENATION; HYPERPOLARIZATION; MAGNETIC FIELD; MAGNETISM; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POLARIZATION; PRIORITY JOURNAL; ANIMAL; ARTICLE; GUINEA PIG;

ANIMALIA;

ANIMALS; CARBON ISOTOPES; CONTRAST MEDIA; GUINEA PIGS; MAGNETIC RESONANCE IMAGING;

EID: 17044379406     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mri.2004.11.031     Document Type: Conference Paper

References (14)

1. C.R. Bowers, and D.P. Weitekamp Transformation of symmetrization order to nuclear-spin magnetization by chemical reaction and nuclear magnetic resonance Phys. Rev. Lett. 57 1986 2645 2648
2. C.R. Bowers, and D.P. Weitekamp Parahydrogen and synthesis allow dramatically enhanced nuclear alignment J. Am. Chem. Soc. 109 1987 5541 5542
3. M.G. Pravica, and D.P. Weitekamp Net alignment by adiabatic transport of parahydrogen addition products to high magnetic field Chem. Phys. Lett. 145 4 1998 255 258
4. 31P by oxidative addition and dipolar relaxation J. Am. Chem. Soc. 111 1989 7267 7269
5. R. Eisenberg, T.C. Eisenschmid, M.S. Chinn, and R.U. Kirss Parahydrogen-induced polarization and polarization transfer in hydrogenation and oxidative addition reactions Adv. Chem. 230 1992 47 74
6. J. Barkemeyer, M. Haake, and J. Bargon Hetero-NMR enhancement via parahydrogen labeling J. Am. Chem. Soc. 117 1995 2927 2928
7. J. Natterer, O. Schedletzky, J. Barkemeyer, J. Bargon, and S.J. Glaser Investigating catalytic processes with parahydrogen: evolution of zero-quantum coherence in AA'X spin systems J. Magn. Reson. 133 1998 92 97
8. J. Barkemeyer, J. Bargon, H. Sengstschmid, and R. Freeman Heteronuclear polarization transfer using selective pulses during hydrogenation with parahydrogen J. Magn. Reson. A120 1996 129 132
9. M. Haake, J. Natterer, and J. Bargon Efficient NMR pulse sequence to transfer the parahydrogen-induced polarization to hetero nuclei J. Am. Soc. 118 1996 8688 8691
10. C.R. Bowers Sensitivity enhancement utilizing parahydrogen D.M. Grant R.K. Harris Encyclopedia of magnetic resonance vol. 9 2002 John Wiley & Sons Ltd Chichester 750 769
11. 13C angiography Magn. Reson. Med. 46 2001 1 5
12. H. Jóhannesson, O. Axelsson, and M.C.R. Karlsson Transfer of para-hydrogen spin order into polarization by diabetic field cycling CR Physique 2004 315 324
13. 13C Br. J. Radiol. 76 2003 S118 S127
14. A. Oppelt, R. Graumann, H. Barfuss, H. Fischer, W. Hartl, and W. Schajor FISP: Eine neue schnelle Pulssequenz für die Kernspintomographie Electromedica 54 1986 15 18