Effects of magnesium sulphate and clonidine on propofol consumption, haemodynamics and postoperative recovery

British Journal of Anaesthesia

Volumn 94, Issue 4, 2005, Pages 438-441

  Altan, A ^a   Turgut, N ^a,b   Yildiz, F ^a   Turkmen A ^a   Ustun H ^a  

^a OKMEYDANI EDUCATION AND RESEARCH HOSPITAL   (Turkey)

^b NONE   (Turkey)

Author keywords

Anaesthetics i.v., propofol; Pharmacology, magnesium sulphate; Premedication, clonidine

Indexed keywords

CISATRACURIUM; CLONIDINE; FENTANYL; ISOTONIC SOLUTION; MAGNESIUM SULFATE; PLACEBO; PROPOFOL;

ADULT; ANALYSIS OF VARIANCE; ANESTHESIA INDUCTION; ARTERIAL PRESSURE; ARTICLE; BOLUS INJECTION; BRADYCARDIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG INFUSION; FEMALE; HEART RATE; HEMODYNAMICS; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SPINE SURGERY; STATISTICAL ANALYSIS;

EID: 17044378616     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aei070     Document Type: Article

References (14)

1. Guglielminotti J, Descraques C, Petitmaire L, Almenzi L, Grenapin O, Mantz J. Effects of premedication on dose requirements for propofol; comparison of clonidine and hydroxyzine. Br J Anaesth 1998; 80: 733-6
2. Aldrete JA, Kroulik D. A post anesthetic recovery score. Anesth Analg 1970; 49: 924-34
3. Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. Anesthesiology 1997; 87: 808-15
4. Cullen PM, Turtle M, Pyrs-Roberts C, Way WL, Dye J. Effects of propofol anesthesia on baroreflex activity in humans. Anesth Analg 1987; 66: 1115-20
5. Coates DP, Monk CR, Prys-Roberts C, Turtle M. Hemodynamic effects of infusions of the emulsion formulation of propofol during nitrous oxide anesthesia in humans. Anesth Analg 1987; 66: 64-70
6. Telci L, Esen F, Akcora D, et al. Evaluation of effects of magnesium sulphate in reducing intraoperative anaesthetic requirements. Eur J Anaesth 2001; 18: 723-9
7. Aldrete JA, Vazeery A. Is magnesium sulfate an anesthetic? Anesth Analg 1989; 68: 186-7
8. Thompson SW, Moscicki JC, Difazio CA. The anesthetic contribution of magnesium sulfate and ritodrine hydrochloride in rats. Anesth Analg 1988; 67: 31-4
9. Van Den Berg AA, Savva D, Honjol NM. Attenuation of the hemodynamic responses to noxious stimuli in patients undergoing cataract surgery. A comparison of magnesium sulphate, esmolol, lignocaine, nitroglycerine and placebo given Lv. with induction of anaesthesia. Eur J Anaesth 1997; 14: 134-47
10. Taittonen M, Kirvela O, Aantaa R, Kanto J. Cardiovascular and metabolic responses to clonidine and midazolam premedication. Eur J Anaesth 1997; 14: 190-6
11. Costello TG, Cormack JR. Clonidine premedication decreases hemodynamic responses to pin head-holder application during craniotomy. Anesth Analg 1998; 86: 1001-4
12. Kulka PJ, Tryba M, Zenz M. Does clonidine modify the hypnotic effect of propofol? Anaesthetist 1993; 42: 630-7
13. Fehr SB, Zalunardo MP, Seifert B, et al. Clonidine decreases propofol requirements during anaesthesia: effect on bispectral index. Br J Anaesth 2001; 86: 627-32
14. Ghignone M, Calvillo O, Quintin L. Anesthesia and hypertension: the effect of clonidine on perioperative, hemodynamics and isoflurane requirements. Anesthesiology 1987; 67: 3-10