A new locus for non-syndromal, autosomal recessive, sensorineural hearing loss (DFNB16) maps to human chromosome 15q21-q22

Journal of Medical Genetics

Volumn 34, Issue 12, 1997, Pages 1015-1017

  Campbell, D A ^a   McHale, D P ^a   Brown, K A ^a   Moynihan, L M ^a   Houseman, M ^a   Karbani, G ^a   Parry, G ^b   Janjua, A H ^b   Newton, V ^c   Al Gazali, L ^d   Markham, A F ^a   Lench, N J ^a   Mueller, R F ^a  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^b ST LUKE S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Autosomal recessive; Autozygosity mapping; Sensorineural deafness

Indexed keywords

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHROMOSOME 15Q; DNA RECOMBINATION; FEMALE; GENE MAPPING; GENETIC LINKAGE; HAPLOTYPE; HUMAN; MALE; MARKER GENE; MIDDLE EAST; PAKISTAN; PERCEPTION DEAFNESS; PRIORITY JOURNAL;

EID: 16944364736     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.34.12.1015     Document Type: Article

References (21)

1. Petit C. Genes responsible for human hereditary deafness: symphony of a thousand. Nat Genet 1996;14:385-91.
2. Van Camp G, Willems PJ, Smith RJH. Nonsyndromic hearing impairment: unparalleled heterogeneity. Am J Hum Genet 1997;60:758-64.
3. Baldwin C, Weiss S, Farrer L, et al. Linkage of congenital recessive deafness (DFNB4) to chromosome 7q31 and evidence for genetic heterogeneity in the Middle Eastern Druze population. Hum Mol Genet 1995;4:1637-42.
4. Fukushima K, Arabandi R, Srisailapathy C, et al. Consanguineous nuclear families used to identify a new locus for recessive non-syndromic hearing loss on 14q. Hum Mol Genet 1995;4:1643-8.
5. Fukushima K, Ramesh A, Srisailapathy CR, et al. An autosomal recessive non-syndromic form of sensorineural hearing loss maps to 3p-DFNB6. Genome Res 1995;5:305-8.
6. Jain P, Fukushima K, Deshmukh D, et al. A human recessive neurosensory non-syndromic hearing impairment locus is a potential homologue of the murine deafness (dn) locus. Hum Mol Genet 1995;4:2391-4.
7. Veske A, Oehlmann R, Younus F, et al. Autosomal recessive non-syndromic deafness locus (DFNB8) maps on chromosome 21q22 in a large consanguineous kindred from Pakistan. Hum Mol Genet 1996;5:165-8.
8. Bonne-Tamir B, DeStefano AL, Briggs CE, et al. Linkage of congenital recessive deafness (gene DFNB10) to chromosome 21q22.3. Am J Hum Genet 1996;58:1254-9.
9. Chaib H, Place C, Salem N, et al. A gene responsible for a sensorineural nonsyndromic recessive deafness maps to chromosome 2p22-23. Hum Mol Genet 1996;5:155-8.
10. Scott DA, Carmi R, Elbedour K, Yosefsberg S, Stone EM, Sheffield VC. An autosomal recessive nonsyndromic-hearing-loss locus identified by DNA pooling using two inbred Bedouin kindreds. Am J Hum Genet 1996;59:385-91.
11. Chaib H, Place C, Salem N, et al. Mapping of DFNB12, a gene for a non-syndromal autosomal recessive deafness, to chromosome 10q21-22. Hum Mol Genet 1996;5:1061-4.
12. Guilford P, Ben Arab S, Blanchard S, et al. A non-syndromic form of neurosensory, recessive deafness maps to the pericentromeric region of chromosome 13q. Nat Genet 1994;6:24-8.
13. Guilford P, Ayadi H, Blanchard S, et al. A human gene responsible for neurosensory, non-syndromic recessive deafness is a candidate homologue of the mouse sh-1 gene. Hum Mol Genet 1994;3:989-93.
14. Friedman TB, Liang Y, Weber J, et al. A gene for congenital, recessive deafness DFNB3 maps to the pericentromeric region of chromosome 17. Nat Genet 1995;9:86-91.
15. Kirshhofer K, Hoover DM, Kenyon JB, et al. Localisation of a gene responsible for an autosomal dominant non-syndromic sensorineural hearing loss to chromosome 15. The molecular biology of hearing and deafness meeting, Bethesda, USA, 1995.
16. Kirshhofer K, Kenyon JB, Hoover DM, et al. Autosomal-dominant congenital severe sensorineural hearing loss: localisation of a disease gene to chromosome 11q by linkage analysis in an Austrian family. Second Workshop of the European Workgroup on Genetics of Hearing Impairment, Milan, Italy, 1996.
17. Kruglyak L, Daly MJ, Lander ES. Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping. Am J Hum Genet 1995;56:519-27.
18. Maw MA, Allen-Powell DR, Goodey RJ, et al. The contribution of the DFNB1 locus to neurosensory deafness in a caucasian population. Am J Hum Genet 1995;57:629-35.
19. Gasparini P, Estivill X, Volpini A, et al. Linkage of DFNB1 to non-syndromic neurosensory autosomal recessive deafness in Mediterranean families. Eur J Hum Genet 1997;5:83-8.
20. Weil D, Blanchard S, Kaplan J, et al. Defective myosin VIIA gene responsible for Usher syndrome type 1B. Nature 1995;374:60-1.
21. Hasson T, Skowron JF, Gilbert DJ, et al. Mapping of unconventional myosins in mouse and human. Genomics 1996;36:431-9.