A fraction unresponsive to growth inhibition by TGF-β among the high-proliferative potential progenitor cells in bone marrow of p53-deficient mice

Leukemia

Volumn 11, Issue 2, 1997, Pages 239-244

  Sasaki, H ^a,b   Matsuda, M ^a   Lu, Y ^a   Ikuta, K ^a   Matsuyama, S ^a   Hirabayashi, Y ^b   Mitsui, H ^b   Matsumura, T ^b   Muramatsu, M ^c   Tsukada, T ^d   Aizawa, S ^d   Inoue, T ^b,e  

^a Department of Pediatrics ^*  (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

^e NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Hematopoietic progenitors; p53; TGF

Indexed keywords

FLUOROURACIL; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; BONE MARROW CELL; CELL GROWTH; CONTROLLED STUDY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC TISSUE; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; STEM CELL; TUMOR SUPPRESSOR GENE;

EID: 16944364443     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400548     Document Type: Article

References (10)

1. Coffey RJ, Sipes NJ, Bascom CC, Graves DR, Pennington CY, Weissman BE, Moses HL. Growth modulation of mouse keratinocytes by transforming growth factors. Cancer Res 1988; 48: 1596-1602.
2. 1 selectively regulates early murine hematopoietic progenitors and inhibits the growth of IL-3-dependent myeloid leukemia cell lines. J Exp Med 1988; 168: 737-750.
3. Keller JR, Mantel C, McNiece IK, Sill KT, Ellingsworth LR, Quesenberry PJ, Sing GK, Ruscetti FW. Transforming growth factor β directly regulates primitive murine hematopoietic cell proliferation. Blood 1990; 75: 596-602.
4. McNiece IK, Bertoncello I, Keller RJ, Ruscetti FW, Hartley CA, Zsebo KM. Transforming growth factor β inhibits the action of stem cell factor on murine and human hematopoietic progenitors. Int J Cell Clon 1992; 10: 80-86.
5. Ellingsworth LR, Brennan JE, Fok K, Rosen DM, Bentz H, Piez KA, Seyedin SM. Antibody to the N-terminal portion of cartilage-inducing factor A and transforming growth factor β. J Biol Chem 1986; 261: 12362-12367.
6. Levine AJ, Momand J, Finlay CA. The p53 tumor suppressor gene. Nature 1991; 351: 453-156.
7. Ahuja H, Bar-Eli M, Advani SH, Benchimol S, Cline MJ. Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia. Proc Natl Acad Sci USA 1989; 86: 6783-6787.
8. Sugimoto K, Toyoshima H, Sakai R, Miyagawa K, Hagiwara K, Hirai H, Ishikawa F, Takaku F. Mutations of the p53 gene in lymphoid leukemia. Blood 1991; 77: 1153-1156.
9. Slingerland JM, Minden MD, Benchimol S. Mutation of the p53 gene in human acute myelogenous leukemia. Blood 1991; 77: 1500-1507.
10. Gaidano G, Ballerini P, Gong JZ, Inghirami G, Neri A, Newcomb EW, Magrath IT, Knowles DM, Dalla-Favera R. p53 mutations in human lymphoid malignancies: association with Burkitt's lymphoma and chronic lymphocytic leukemia. Proc Natl Acad Sci USA 1991; 88: 5413-5417.