Reductions in viral load and increases in T lymphocyte numbers in treatment-naive patients with advanced HIV-1 infection treated with ritonavir, zidovudine and zalcitabine triple therapy

Antiviral Therapy

Volumn 2, Issue 3, 1997, Pages 175-183

  Leibowitch, J ^a  

^a Hop Raymond Poincare0   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; NUCLEOSIDE ANALOG; PROTEINASE INHIBITOR; RITONAVIR; ZALCITABINE; ZIDOVUDINE;

ADULT; ANEMIA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; DRUG EFFICACY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MALE; MOUTH ULCER; MULTICENTER STUDY; NAUSEA; ORAL DRUG ADMINISTRATION; PARESTHESIA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; VIREMIA; VOMITING;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; CD8-POSITIVE T-LYMPHOCYTES; DRUG THERAPY, COMBINATION; FEMALE; HIV-1; HUMANS; MALE; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RITONAVIR; RNA, VIRAL; ZALCITABINE; ZIDOVUDINE;

EID: 16944362619     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Khan JO, Lagakos SW, Richman DD, Cross A, Pettinelli C, Liou SH, Brown M, Volberding PA, Crumpacker CS, Beall G et al. A controlled trial comparing continued zidovudine with didanosine in human immunodeficiency virus infection. New England journal of Medicine 1992; 327:581-587.
2. Pollard R, Peterson D, Hardy D, Pedneault L, McLaren C, Skovronski J, Connaughton E, Grosso R, Reynolds L, Rutkiewicz V, Cross A, Dunkle L & Smaldone L. Antiviral effect and safety of stavudine (D4T) and didanosine (DDI) combination therapy in HIV-infected subjects in ongoing pilot randomized double-blinded trial. 3rd Conference on Retroviruses and Opportunistic Infections, 28 January-1 February 1996 Washington, USA. Abstract 197.
3. Spruance SL, Pavia AT, Peterson D, Berry A, Pollard R, Patterson TF, Frank I, Remick SC, Thompson M, MacArthur RD et al. Didanosine compared with continuation of zidovudine in HIV-infected patients with signs of clinical deterioration while receiving zidovudine: a randomized, double-blind clinical trial. Annals of Internal Medicine 1994; 120:360-368.
4. Meng T-Ch, Fischl MA, Ahmad AM, Spector SA, Bennett D, Bassiakos Y, Lai S, Wright B & Richman DD. Combination therapy with zidovudine and dideoxycytidine in patients with advanced human immunodeficiency virus infection. Annals of Internal Medicine 1992; 116:13-20.
5. Fischl MA, Richman DD, Grieco MH, Gottleib MS, Volberding PA, Laskin OL, Leedom JM, Groopman JE, Mildvan D, Schooley RT et al. The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex: a double-blind, placebo-controlled trial. New England Journal of Medicine 1987; 317:185-191.