Tissue-specific engraftment after in utero transplantation of allogeneic mesenchymal stem cells into sheep fetuses

American Journal of Obstetrics and Gynecology

Volumn 192, Issue 4, 2005, Pages 1044-1052

  Schoeberlein, Andreina ^a   Holzgreve, Wolfgang ^a   Dudler, Lisbeth ^a   Hahn, Sinuhe ^a   Surbek, Daniel V ^a,b  

^a UNIVERSITY WOMEN S HOSPITAL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Allogeneic; In utero transplantation; Mesenchymal stem cells; Sheep

Indexed keywords

ALLOGENEIC STEM CELL TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; BLOOD; BONE MARROW; BRAIN; CELL ADHESION; CELL CULTURE; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CONTROLLED STUDY; ECHOGRAPHY; FEMALE; FETUS; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC DISORDER; GESTATIONAL AGE; IMMUNOHISTOCHEMISTRY; IN UTERO STEM CELL TRANSPLANTATION; KIDNEY; LIVER; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PERITONEAL CAVITY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SHEEP; SPLEEN; SURVIVAL RATE; THYMUS; TISSUE REGENERATION;

EID: 16844377227     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2005.01.031     Document Type: Conference Paper

References (28)

1. A.W. Flake, and E.D. Zanjani In utero hematopoietic stem cell transplantation: ontogenic opportunities and biologic barriers Blood 94 1999 2179 2191
2. J.F. Zhong, Y. Zhan, W.F. Anderson, and Y. Zhao Murine hematopoietic stem cell distribution and proliferation in ablated and nonablated bone marrow transplantation Blood 100 2002 3521 3526
3. P. Benveniste, C. Cantin, D. Hyam, and N.N. Iscove Hematopoietic stem cells engraft in mice with absolute efficiency Nat Immunol 4 2003 708 713
4. D.J. Prockop Marrow stromal cells as stem cells for nonhematopoietic tissues Science 276 1997 71 74
5. M.F. Pittenger, A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, and J.D. Mosca Multilineage potential of adult human mesenchymal stem cells Science 284 1999 143 147
6. F. Barry, and J. Murphy Mesenchymal stem cells: clinical applications and biological characterization Int.J Biochem Cell Biol 36 2004 568 584
7. T. MacKenzie, A. Shaaban, A. Radu, and A. Flake Engraftment of bone marrow and fetal liver cells after in utero transplantation in MDX mice J Pediatr Surg 37 2002 1058 1064
8. E.M. Horwitz, D.J. Prockop, P.L. Gordon, W.W. Koo, L.A. Fitzpatrick, and M.D. Neel Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta Blood 97 2001 1227 1231
9. G. Almeida-Porada, A.W. Flake, H.A. Glimp, and E.D. Zanjani Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero Exp Hematol 27 1999 1569 1575
10. W.A. Noort, A. Kruisselbrink, P. in't Anker, M. Kruger, R. van Bezooijen, and R. de Paus Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice Exp Hematol 30 2002 870
11. C. Campagnoli, I. Bellantuono, S. Kumar, L. Fairbairn, I. Roberts, and N. Fisk High transduction efficiency of circulating first trimester fetal mesenchymal stem cells: potential targets for in utero ex vivo gene therapy BJOG 109 2002 952 954
12. C. Campagnoli, I.A. Roberts, S. Kumar, P.R. Bennett, I. Bellantuono, and N.M. Fisk Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow Blood 98 2001 2396 2402
13. H.L. Jessop, B.S. Noble, and A. Cryer The differentiation of a potential mesenchymal stem cell population within ovine bone marrow Biochem Soc Trans 22 1994 248S
14. K. Le Blanc, C. Tammik, K. Rosendahl, E. Zetterberg, and O. Ringden HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells Exp Hematol 31 2003 890 896
15. T.C. MacKenzie, and A.W. Flake Human mesenchymal stem cells persist, demonstrate site-specific multipotential differentiation, and are present in sites of wound healing and tissue regeneration after transplantation into fetal sheep Blood Cells Mol Dis 27 2001 601 604
16. C. Götherström, O. Ringdén, M. Westgren, C. Tammik, and K. Le Blanc Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells Bone Marrow Transplant 32 2003 265 272
17. D. Surbek, A. Young, E. Danzer, A. Schoeberlein, L. Dudler, and W. Holzgreve Ultrasound-guided stem cell sampling from the early ovine fetus for prenatal ex vivo gene therapy Am J Obstet Gynecol 187 2002 960 963
18. A. Young, W. Holzgreve, L. Dudler, A. Schoeberlein, and D. Surbek Engraftment of human cord blood-derived stem cells in preimmune ovine fetuses after ultrasound-guided in utero transplantation Am J Obstet Gynecol 189 2003 1 4
19. A. Schoeberlein, W. Holzgreve, L. Dudler, S. Hahn, and D. Surbek In utero transplantation of autologous and allogeneic fetal liver stem cells in ovine fetuses Am J Obstet Gynecol 191 2004 1030 1036
20. C. Coutelle, M. Themis, S. Waddington, L. Gregory, M. Nivsarkar, and S. Buckley The hopes and fears of in utero gene therapy for genetic disease - a review Placenta 24 2003 S114 S121
21. T.C. MacKenzie, and A.W. Flake Multilineage differentiation of human MSC after in utero transplantation Cytotherapy 3 2001 403 405
22. J.A. Airey, G. Almeida-Porada, E.J. Colletti, C.D. Porada, J. Chamberlain, and M. Movsesian Human mesenchymal stem cells form Purkinje fibers in fetal sheep heart Circulation 109 2004 1401 1407
23. G. Munoz-Elias, A.J. Marcus, T.M. Coyne, D. Woodbury, and I.B. Black Adult bone marrow stromal cells in the embryonic brain: engraftment, migration, differentiation, and long-term survival J Neurosci 24 2004 4585 4595
24. B. Stonestreet, G. Sadowska, A. McKnight, C. Patlak, and K. Petersson Exogenous and endogenous corticosteroids modulate blood-brain barrier development in the ovine fetus Am J Physiol Regulatory Integrative Comp Physiol 279 2000 R468 R477
25. E.D. Rosen, I. Cornelissen, Z. Liang, A. Zollman, M. Casad, and J. Roahrig In utero transplantation of wild-type fetal liver cells rescues factor X-deficient mice from fatal neonatal bleeding diatheses J Thromb Haemost 1 2003 19 27
26. C.D. Porada, N. Tran, M. Eglitis, R.C. Moen, L. Troutman, and A.W. Flake In utero gene therapy: transfer and long-term expression of the bacterial neo(r) gene in sheep after direct injection of retroviral vectors into preimmune fetuses Hum Gene Ther 9 1998 1571 1585
27. F. Deschaseaux, F. Gindraux, R. Saadi, L. Obert, D. Chalmers, and P. Herve Direct selection of human bone marrow mesenchymal stem cells using an anti-CD49a antibody reveals their CD45med, low phenotype Br J Haematol 122 2003 506 517
28. E.M. Horwitz, P.L. Gordon, W.K. Koo, J.C. Marx, M.D. Neel, and R.Y. McNall Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone Proc Natl Acad Sci U S A 99 2002 8932 8937