Use of quantitative real-time PCR to monitor the response of Chlamydophila felis infection to doxycycline treatment

Journal of Clinical Microbiology

Volumn 43, Issue 4, 2005, Pages 1858-1864

  Dean, Rachel ^a   Harley, Ross ^a   Helps, Chris ^a   Caney, Sarah ^a   Gruffydd Jones, Tim ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; DOXYCYCLINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; BACTERIUM DETECTION; CAT; CHLAMYDOPHILA; CHLAMYDOPHILA FELIS; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG INDICATION; DRUG RESPONSE; INFECTION COMPLICATION; INFECTION CONTROL; MONITORING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; TREATMENT OUTCOME;

ANIMALS; ANTI-BACTERIAL AGENTS; CAT DISEASES; CATS; CHLAMYDOPHILA; CHLAMYDOPHILA INFECTIONS; CONJUNCTIVITIS, BACTERIAL; DNA, BACTERIAL; DOXYCYCLINE; FEMALE; MALE; POLYMERASE CHAIN REACTION; TREATMENT OUTCOME;

EID: 16844369924     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.43.4.1858-1864.2005     Document Type: Article

References (16)

1. Gaillard, E. T., A. M. Hargis, D. J. Prieur, J. F. Evermann, and A. S. Dhillon. 1984. Pathogenesis of feline gastric chlamydial infection. Am. J. Vet. Res. 45:2314-2321.
2. Grayston, J. T., S. P. Wang, L. J. Yeh, and C. C. Kuo. 1985. Importance of reinfection in the pathogenesis of trachoma. Rev. Infect. Dis. 7:717-725.
3. Greene, C. E. 1998. Chlamydial infections. In C. E. Greene (ed.), Infectious diseases of the dog and cat, 2nd ed. W. B. Saunders, Philadelphia, Pa.
4. Hargis, A. M., D. J. Prieur, and E. T. Gaillard. 1983. Chlamydial infection of the gastric mucosal in twelve cats. Vet. Pathol. 20:170-178.
5. Helps, C., N. Reeves, K. Egan, P. Howard, and D. Harbour. 2003. Detection of Chlamydophila felis and feline herpesvirus by multiplex real-time PCR analysis. J. Clin. Microbiol. 41:2734-2736.
6. Masubuchi, K., H. Nosaka, K. Iwamoto, T. Kokubu, M. Yamanaka, and Y. Shimizu. 2002. Experimental infection of cats with Chlamydophila felis. J. Vet. Med. Sci. 64:1165-1168.
7. McDonald, M., B. J. Willett, O. Jarrett, and D. D. Addie. 1998. A comparison of DNA amplification, isolation and serology for the detection of Chlamydia psittaci infection in cats. Vet. Rec. 143:97-101.
8. Owen, W. M. A., C. P. Sturgess, D. A. Harbour, K. Egan, and T. Gruffydd-Jones. 2003. Efficacy of azithromycin for the treatment of feline chlamydophilosis. J. Feline Med. Surg. 5:305-311.
9. Shewen, P. E., R. C. Povey, and M. R. Wilson. 1978. Feline chlamydial infection. Can. Vet. J. 19:289-292.
10. Sparkes, A. H., S. M. A. Caney, C. P. Sturgess, and T. Gruffydd-Jones. 1999. The clinical efficacy of topical and systemic therapy for the treatment of feline ocular chlamydiosis. J. Feline Med. Surg. 1:31-35.
11. Sturgess, C. P., T. Gruffydd-Jones, D. A. Harbour, and R. L. Jones. 2001. Controlled study of the efficacy of clavulanic acid-potentiated amoxicillin in the treatment of Chlamydia psittaci in cats. Vet. Rec. 149:73-76.
12. Sykes, J. E., V. P. Studdert, and G. F. Browning. 1999. Comparison of the polymerase chain reaction and culture for the detection of Chlamydia psittaci in untreated and doxycycline-treated experimentally infected cats. J. Vet. Intern. Med. 13:146-152.
13. Sykes, J. E. 2004. Chlamydial infections. In E. A. Chandler, C. J. Gaskell, and R. M. Gaskell (ed.), Feline medicine and therapeutics, 3rd ed. Blackwell Publishing, Oxford, United Kingdom.
14. Wills, J. M. 1986. Chlamydial infection in cats. Ph.D. thesis. University of Bristol, Bristol, United Kingdom.
15. Wills, J. M., T. J. Gruffydd-Jones, S. J. Richmond, R. M. Gaskell, and F. J. Bourne. 1987. Effect of vaccination on feline Chlamydia psittaci infection. Infect. Immun. 55:2653-2657.
16. Wills, J. M., P. E. Howard, T. J. Gruffydd-Jones, and C. M. Wathes. 1988. Prevalence of Chlamydia psittaci in different cat populations in Britain. J. Small Anim. Practice 29:327-339.