Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: Influence of HIV infection on clindamycin toxicity in vitro

Journal of Clinical Pharmacology

Volumn 45, Issue 3, 2005, Pages 346-351

  Wijsman, John A ^a   Dekaban, Gregory A ^a   Rieder, Michael J ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b CHILDREN S HOSPITAL OF WESTERN ONTARIO   (Canada)

Author keywords

Adverse drug reactions; Clindamycin; HIV infection; Hypersensitivity; Sulphamethoxazole; Toxicity

Indexed keywords

CLINDAMYCIN; DRUG METABOLITE; PRIMAQUINE; PYRIMETHAMINE; SULFAMETHOXAZOLE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CELL DEATH; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG HYPERSENSITIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; MICROSOME;

ANIMALS; ANTI-INFECTIVE AGENTS; BIOTRANSFORMATION; CELL LINE; CELL SURVIVAL; CLINDAMYCIN; COCULTURE TECHNIQUES; DRUG COMBINATIONS; DRUG HYPERSENSITIVITY; HIV; MICE; MICROSOMES; PRIMAQUINE; PYRIMETHAMINE; SULFAMETHOXAZOLE; T-LYMPHOCYTES;

EID: 16844365738     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/0091270004272670     Document Type: Article

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