A guided inquiry experiment for the measurement of activation energies in the biophysical chemistry laboratory: Decarboxylation of pyrrole-2-carboxylate

Biochemistry and Molecular Biology Education

Volumn 33, Issue 2, 2005, Pages 123-127

  Hutchinson, Kelly M ^a,b,c   Bretz, Stacey Lowery ^b   Mettee, Howard D ^b   Smiley, Jeffrey A ^b  

^a NAZARETH COLLEGE   (United States)

^b YOUNGSTOWN STATE UNIVERSITY   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE;

AB INITIO CALCULATION; ACIDITY; ARTICLE; DECARBOXYLATION; ENERGY; ENZYME MECHANISM; LABORATORY; PHYSICAL CHEMISTRY; REACTION ANALYSIS; TEMPERATURE DEPENDENCE; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 16844363612     PISSN: 14708175     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmb.2005.494033022425     Document Type: Article

References (17)

1. th Ed., McGraw-Hill, New York.
2. R. C. Barile, L. P. Michiels (1983) An activation energy experiment for a second-order reaction in a single laboratory period, J. Chem. Educ. 60, 154.
3. K. R. Adams, M. B. Meyers (1985) Activation energies for an enzyme-catalyzed and acid-catalyzed hydrolysis, J. Chem Educ. 62, 86-88.
4. B. P. Coppola, R. G. Lawton (1995) Who has the same substance that I have? A blueprint for collaborative learning activities, J. Chem. Educ. 72, 1120-1122.
5. R. W. Ricci, M. A. Ditzler (1991) Discovery chemistry: A laboratory-centered approach to teaching general chemistry, J. Chem. Educ. 68, 228-231.
6. M. A. Ditzler, R. W. Ricci (1994) Discovery chemistry: Balancing creativity and structure, J. Chem. Educ. 71, 685-688.
7. L. T. Tien, D. Rickey, A. M. Stacy (1999) The MORE thinking frame: Guiding students; Thinking in the laboratory, J. Coll. Sci. Tchg. 28, 318-324.
8. M. M. Cooper (1995) Cooperative learning: An approach for large enrollment courses, J. Chem. Educ. 72, 162.
9. R. M. Felder, R. Brent (2001) Effective strategies for cooperative learning, J. Cooperation & Collaboration in College Teaching 10, 69-75.
10. G. E. Dunn, G. K. J. Lee (1971) Kinetic and mechanism of the decarboxylation of pyrrole-2-carboxylic acid in aqueous solution, Can. J. Chem. 49, 1032-1035.
11. M. Wieser, N. Fujii, T. Yoshida, T. Nagasawa (1998) Carbon dioxide fixation by reversible pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910, Eur. J. Biochem. 257, 495-499.
12. M. Wieser, T. Yoshida, T. Nagasawa (1998) Microbial synthesis of pyrrole-2-carboxylate by Bacillus megaterium PYR2910 Tetrahedron Lett. 39, 4309-4310.
13. 2. Chem. Comm. 2001, 2194-2195.
14. A. M. Heacock, E. Adams (1975) Formation and excretion of pyrrole-2-carboxylic acid. Whole animal and enzyme studies in the rat. J. Biol. Chem. 250, 2599-608.
15. A. Radzicka, R. Wolfenden (1995) A proficient enzyme. Science 267, 90-93.
16. R. Boyer (2003) Concepts and skills in the biochemistry/molecular biology lab. Biochem. Mol. Biol. Ed. 31, 102-105.
17. American Chemical Society Committee on Professional Training (1992) Guidelines for Undergraduate Professional Education in Chemistry, American Chemical Society, Washington, D. C.