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Volumn 25, Issue 4, 2005, Pages 319-333

Treatment of hyperlipoproteinemia with pantethine: A review and analysis of efficacy and tolerability

Author keywords

Cholesterol; Hyperlipidemia; Hyperlipoproteinemia; Lipids; Pantethine

Indexed keywords

ACIPIMOX; BEZAFIBRATE; CHOLESTEROL; FENOFIBRATE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PANTETHINE; TRIACYLGLYCEROL;

EID: 16844363076     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nutres.2004.12.009     Document Type: Article
Times cited : (30)

References (55)
  • 1
    • 33747397003 scopus 로고    scopus 로고
    • The World Health Organization
    • The World Health Organization CVD prevention and control: missed opportunities www.who.int/cardiovascular_disease/prevention_contol/en/ [accessed August 2003]
    • CVD Prevention and Control: Missed Opportunities
  • 2
    • 0037227270 scopus 로고    scopus 로고
    • Understanding risk in hypercholesterolemia
    • J. LaRosa Understanding risk in hypercholesterolemia Clin Cardiol 26 Suppl. I 2003 I3 I6
    • (2003) Clin Cardiol , vol.26 , Issue.1 SUPPL.
    • Larosa, J.1
  • 3
    • 0023029454 scopus 로고
    • Incidence of coronary heart disease and lipoprotein cholesterol levels: The Framingham Study
    • W. Castelli, R. Garrison, P. Wilson, R. Abbott, S. Kalousdian, and W. Kannel Incidence of coronary heart disease and lipoprotein cholesterol levels: the Framingham Study JAMA 256 1986 2835 2838
    • (1986) JAMA , vol.256 , pp. 2835-2838
    • Castelli, W.1    Garrison, R.2    Wilson, P.3    Abbott, R.4    Kalousdian, S.5    Kannel, W.6
  • 4
    • 0003775053 scopus 로고    scopus 로고
    • American Heart Association American Heart Association Dallas (Tex)
    • American Heart Association Heart disease and stroke statistics-2003 update 2002 American Heart Association Dallas (Tex)
    • (2002) Heart Disease and Stroke statistics-2003 Update
  • 5
    • 0037225293 scopus 로고    scopus 로고
    • Treating hypercholesterolemia: Looking forward
    • A. Gotto Treating hypercholesterolemia: looking forward Clin Cardiol 26 Suppl. I 2003 I21 I28
    • (2003) Clin Cardiol , vol.26 , Issue.1 SUPPL.
    • Gotto, A.1
  • 6
    • 0037051164 scopus 로고    scopus 로고
    • Myopathy and rhabdomyolysis with lipid lowering drugs
    • C. Hodel Myopathy and rhabdomyolysis with lipid lowering drugs Toxicol Lett 128 2002 159 168
    • (2002) Toxicol Lett , vol.128 , pp. 159-168
    • Hodel, C.1
  • 7
    • 0037146230 scopus 로고    scopus 로고
    • Combination therapy for dyslipidemia: Safety and regulatory considerations
    • M. Davidson Combination therapy for dyslipidemia: safety and regulatory considerations Am J Cardiol 90 Suppl. 2002 k50 k60
    • (2002) Am J Cardiol , vol.90 , Issue.SUPPL.
    • Davidson, M.1
  • 8
    • 0034882005 scopus 로고    scopus 로고
    • Effects of yoghurt enriched with plant sterols on serum lipids in patients with moderate hypercholesterolaemia
    • R. Volpe, L. Niittynen, R. Korpela, C. Sirtori, A. Bucci, and N. Fraone Effects of yoghurt enriched with plant sterols on serum lipids in patients with moderate hypercholesterolaemia Br J Nutr 86 2001 233 239
    • (2001) Br J Nutr , vol.86 , pp. 233-239
    • Volpe, R.1    Niittynen, L.2    Korpela, R.3    Sirtori, C.4    Bucci, A.5    Fraone, N.6
  • 9
    • 0037343978 scopus 로고    scopus 로고
    • Treatment of patients with lipid disorders in the primary care setting: New treatment guidelines and their implications
    • J. Keenan Treatment of patients with lipid disorders in the primary care setting: new treatment guidelines and their implications South Med J 96 2003 266 275
    • (2003) South Med J , vol.96 , pp. 266-275
    • Keenan, J.1
  • 10
    • 0344081535 scopus 로고    scopus 로고
    • Pantethine: A review of its biochemistry and therapeutic applications
    • G. Kelly Pantethine: a review of its biochemistry and therapeutic applications Altern Med Rev 2 1997 365 377
    • (1997) Altern Med Rev , vol.2 , pp. 365-377
    • Kelly, G.1
  • 11
    • 0035897696 scopus 로고    scopus 로고
    • Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults: Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III)
    • Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults: executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) JAMA 285 2001 2486 2497
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 12
    • 0025922955 scopus 로고
    • Treatment of hyperlipidemia in diabetic patients on dialysis with a physiological substance
    • F. Coronel, F. Tornero, J. Torrente, P. Naranjo, P. DeOleo, and M. Marcia Treatment of hyperlipidemia in diabetic patients on dialysis with a physiological substance Am J Nephrol 11 1991 32 36
    • (1991) Am J Nephrol , vol.11 , pp. 32-36
    • Coronel, F.1    Tornero, F.2    Torrente, J.3    Naranjo, P.4    Deoleo, P.5    Marcia, M.6
  • 13
    • 0026043099 scopus 로고
    • Confronto dell'efficacia di pantetina, acipimox e bezafibato sui lipidi plasmatici ed indice di rischio cardiovascolare in diabetici dislipidemici
    • L. Tonutti, C. Taboga, and C. Noacco Confronto dell'efficacia di pantetina, acipimox e bezafibato sui lipidi plasmatici ed indice di rischio cardiovascolare in diabetici dislipidemici Minerva Med 82 1991 657 663
    • (1991) Minerva Med , vol.82 , pp. 657-663
    • Tonutti, L.1    Taboga, C.2    Noacco, C.3
  • 14
    • 0025111238 scopus 로고
    • Evaluation of the hypocholesterolemic activity of pantethine in perimenopausal women
    • P. Binaghi, G. Cellina, G. LoCicero, F. Bruschi, E. Porcaro, and M. Penotti Evaluation of the hypocholesterolemic activity of pantethine in perimenopausal women Minerva Med 81 1990 475 479
    • (1990) Minerva Med , vol.81 , pp. 475-479
    • Binaghi, P.1    Cellina, G.2    Locicero, G.3    Bruschi, F.4    Porcaro, E.5    Penotti, M.6
  • 15
    • 0024710576 scopus 로고
    • A double-blind clinical trial: The effects of pantethine on serum lipids in patients with hyperlipidemia
    • Z. Lu A double-blind clinical trial: the effects of pantethine on serum lipids in patients with hyperlipidemia Zhonghua Xin Xue Guan Bing Za Zhi 17 1989 221 223
    • (1989) Zhonghua Xin Xue Guan Bing Za Zhi , vol.17 , pp. 221-223
    • Lu, Z.1
  • 16
    • 0023501986 scopus 로고
    • Lowering effect of pantethine on plasma beta-thromboglobulin and lipids in diabetes mellitus
    • M. Eto, K. Watanabe, N. Chonan, and K. Ishii Lowering effect of pantethine on plasma beta-thromboglobulin and lipids in diabetes mellitus Artery 15 1987 1 12
    • (1987) Artery , vol.15 , pp. 1-12
    • Eto, M.1    Watanabe, K.2    Chonan, N.3    Ishii, K.4
  • 17
    • 0023218412 scopus 로고
    • Effect of oral treatment with pantethine on platelet and plasma phospholipids in type IIa hyperlipoproteinemia
    • D. Prisco, P. Rogasi, M. Matucci, R. Paniccia, R. Abbate, and G. Gensini Effect of oral treatment with pantethine on platelet and plasma phospholipids in type IIa hyperlipoproteinemia J Vasc Dis 38 1987 241 247
    • (1987) J Vasc Dis , vol.38 , pp. 241-247
    • Prisco, D.1    Rogasi, P.2    Matucci, M.3    Paniccia, R.4    Abbate, R.5    Gensini, G.6
  • 18
    • 0023010856 scopus 로고
    • Treatment of hyperlipidemias complicated by cardiovascular diseases in the elderly: Results of an open short-term study with pantethine
    • F. Bellani, R. Colnago, M. Meregalli, P. Scarpazza, O. Sesia, and C. Donati Treatment of hyperlipidemias complicated by cardiovascular diseases in the elderly: results of an open short-term study with pantethine Curr Ther Res 40 1986 912 916
    • (1986) Curr Ther Res , vol.40 , pp. 912-916
    • Bellani, F.1    Colnago, R.2    Meregalli, M.3    Scarpazza, P.4    Sesia, O.5    Donati, C.6
  • 20
    • 0022651060 scopus 로고
    • Pantethine improves the lipid abnormalities of chronic hemodialysis patients: Results of a multicenter clinical trial
    • C. Donati, G. Barbi, G. Cairo, G.F. Prati, and E. Degli Esposti Pantethine improves the lipid abnormalities of chronic hemodialysis patients: results of a multicenter clinical trial Clin Nephrol 25 1986 70 74
    • (1986) Clin Nephrol , vol.25 , pp. 70-74
    • Donati, C.1    Barbi, G.2    Cairo, G.3    Prati, G.F.4    Degli Esposti, E.5
  • 21
    • 0022477138 scopus 로고
    • Effectiveness of long-term treatment with pantethine in patients with dyslipidemia
    • L. Arsenio, P. Bodria, G. Magnati, A. Strata, and R. Trovato Effectiveness of long-term treatment with pantethine in patients with dyslipidemia Clin Ther 8 1986 537 545
    • (1986) Clin Ther , vol.8 , pp. 537-545
    • Arsenio, L.1    Bodria, P.2    Magnati, G.3    Strata, A.4    Trovato, R.5
  • 23
    • 0022155044 scopus 로고
    • Impiego della pantetina nella dislipidemia dell'uremico cronico in trattamento dialitico
    • F. Bergesio, R. Ciuti, D. Innocenti, G. Galli, and V. Frizzi Impiego della pantetina nella dislipidemia dell'uremico cronico in trattamento dialitico G Clin Med 66 1985 433 440
    • (1985) G Clin Med , vol.66 , pp. 433-440
    • Bergesio, F.1    Ciuti, R.2    Innocenti, D.3    Galli, G.4    Frizzi, V.5
  • 24
    • 0022395399 scopus 로고
    • Changes in fatty acid composition of the single platelet phospholipids induced by pantethine treatment
    • G.F. Gensini, D. Prisco, P.G. Rogasi, M. Matucci, and G.G. Neri Serneri Changes in fatty acid composition of the single platelet phospholipids induced by pantethine treatment Int J Clin Pharmacol Res 5 1985 309 318
    • (1985) Int J Clin Pharmacol Res , vol.5 , pp. 309-318
    • Gensini, G.F.1    Prisco, D.2    Rogasi, P.G.3    Matucci, M.4    Neri Serneri, G.G.5
  • 25
    • 0022183272 scopus 로고
    • Treatment of hypercholesterolemia with pantethine and fenofibrate: An open randomized study on 43 subjects
    • L. Cattin, P. DaCol, M. Fonda, M. Mameli, L. Pilotto, and D. Vanuzzo Treatment of hypercholesterolemia with pantethine and fenofibrate: an open randomized study on 43 subjects Curr Ther Res 38 1985 386 395
    • (1985) Curr Ther Res , vol.38 , pp. 386-395
    • Cattin, L.1    Dacol, P.2    Fonda, M.3    Mameli, M.4    Pilotto, L.5    Vanuzzo, D.6
  • 27
    • 0022408289 scopus 로고
    • Effetto della terapia con pantetina in uremici cronici emodializzati con iperlipoproteinemia di tipo IV
    • G. Seghieri, G. Maffucci, G. Toscano, F. Santoni, S. Tuci, and L. DeGiorgio Effetto della terapia con pantetina in uremici cronici emodializzati con iperlipoproteinemia di tipo IV G Clin Med 66 1985 187 192
    • (1985) G Clin Med , vol.66 , pp. 187-192
    • Seghieri, G.1    Maffucci, G.2    Toscano, G.3    Santoni, F.4    Tuci, S.5    Degiorgio, L.6
  • 29
    • 0021677287 scopus 로고
    • Changes in the very low density lipoprotein distribution of apolipoproteins C-III2, C-III1, C-III0, C-II and apolipoprotein e after pantethine administration
    • O. Bosello, L. Cominacini, U. Garrbin, F. Ferrari, I. Zocca, and A. Davoli Changes in the very low density lipoprotein distribution of apolipoproteins C-III2, C-III1, C-III0, C-II and apolipoprotein E after pantethine administration Acta Ther 10 1984 421 430
    • (1984) Acta Ther , vol.10 , pp. 421-430
    • Bosello, O.1    Cominacini, L.2    Garrbin, U.3    Ferrari, F.4    Zocca, I.5    Davoli, A.6
  • 30
    • 0021194386 scopus 로고
    • Pantethine in the treatment of hypercholesterolemia: A randomized double-blind trial versus tiadenol
    • P. Da Col, L. Cattin, M. Fonda, M. Mameli, and F. Feruglio Pantethine in the treatment of hypercholesterolemia: a randomized double-blind trial versus tiadenol Curr Ther Res 36 1984 314 321
    • (1984) Curr Ther Res , vol.36 , pp. 314-321
    • Da Col, P.1    Cattin, L.2    Fonda, M.3    Mameli, M.4    Feruglio, F.5
  • 31
    • 0021335866 scopus 로고
    • Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia
    • A. Gaddi, G.C. Descovich, G. Noseda, C. Fragiacomo, L. Colombo, and A. Craveri Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia Atherosclerosis 50 1984 73 83
    • (1984) Atherosclerosis , vol.50 , pp. 73-83
    • Gaddi, A.1    Descovich, G.C.2    Noseda, G.3    Fragiacomo, C.4    Colombo, L.5    Craveri, A.6
  • 32
    • 0021687849 scopus 로고
    • Effects of pantethine on lipids and apolipoproteins in hypercholesterolemic diabetic and non-diabetic patients
    • R. Miccoli, P. Marchetti, T. Sampietro, L. Benzi, M. Tognarelli, and R. Navalesi Effects of pantethine on lipids and apolipoproteins in hypercholesterolemic diabetic and non-diabetic patients Curr Ther Res 36 1984 545 549
    • (1984) Curr Ther Res , vol.36 , pp. 545-549
    • Miccoli, R.1    Marchetti, P.2    Sampietro, T.3    Benzi, L.4    Tognarelli, M.5    Navalesi, R.6
  • 33
    • 0021743722 scopus 로고
    • Effect of pantethine on the subfractions of HDL in dyslipidemic patients
    • M. Maioli, A. Pacifico, and G. Cherchi Effect of pantethine on the subfractions of HDL in dyslipidemic patients Curr Ther Res 35 1984 307 311
    • (1984) Curr Ther Res , vol.35 , pp. 307-311
    • Maioli, M.1    Pacifico, A.2    Cherchi, G.3
  • 35
    • 0020980381 scopus 로고
    • The lipid lowering effect of pantethine in hyperlipidemic patients: A clinical investigation
    • F. Galeone, A. Scalabrino, F. Giuntoli, A. Birindelli, G. Panigada, and A. Rossi The lipid lowering effect of pantethine in hyperlipidemic patients: a clinical investigation Curr Ther Res 34 1983 383 390
    • (1983) Curr Ther Res , vol.34 , pp. 383-390
    • Galeone, F.1    Scalabrino, A.2    Giuntoli, F.3    Birindelli, A.4    Panigada, G.5    Rossi, A.6
  • 36
    • 0021881123 scopus 로고
    • The effects of pantethine on lipid and lipoprotein abnormalities in survivors of cerebral infarction
    • A. Murai, T. Miyahara, T. Tanaka, Y. Sako, N. Nishimura, and M. Kameyama The effects of pantethine on lipid and lipoprotein abnormalities in survivors of cerebral infarction Artery 12 1983 234 243
    • (1983) Artery , vol.12 , pp. 234-243
    • Murai, A.1    Miyahara, T.2    Tanaka, T.3    Sako, Y.4    Nishimura, N.5    Kameyama, M.6
  • 37
    • 0020679851 scopus 로고
    • Effect of pantethine on lipids, lipoproteins and apolipoproteins in man
    • P. Avogaro, G. Bittolo, and M. Fusello Effect of pantethine on lipids, lipoproteins and apolipoproteins in man Curr Ther Res 33 1983 488 493
    • (1983) Curr Ther Res , vol.33 , pp. 488-493
    • Avogaro, P.1    Bittolo, G.2    Fusello, M.3
  • 38
    • 0019946468 scopus 로고
    • Pantethine: A physiological lipomodulating agent in the treatment of hyperlipidemias
    • G. Maggi, C. Donati, and G. Criscuoli Pantethine: a physiological lipomodulating agent in the treatment of hyperlipidemias Curr Ther Res 32 1982 380 386
    • (1982) Curr Ther Res , vol.32 , pp. 380-386
    • Maggi, G.1    Donati, C.2    Criscuoli, G.3
  • 39
    • 0019794794 scopus 로고
    • Influence of pantethine on platelet volume, microviscosity, lipid composition and functions in diabetes mellitus with hyperlipidemia
    • K. Hiramatsu, H. Nozaki, and S. Arimori Influence of pantethine on platelet volume, microviscosity, lipid composition and functions in diabetes mellitus with hyperlipidemia Tokai J Exp Clin Med 6 1981 49 57
    • (1981) Tokai J Exp Clin Med , vol.6 , pp. 49-57
    • Hiramatsu, K.1    Nozaki, H.2    Arimori, S.3
  • 41
    • 0023103082 scopus 로고
    • Pantethine inhibits cholesterol and fatty acid synthesis and stimulates carbon dioxide formation in isolated rat hepatocytes
    • G. Cighetti, M. DelPuppo, R. Paroni, E. Fiorica, and M. Kienle Pantethine inhibits cholesterol and fatty acid synthesis and stimulates carbon dioxide formation in isolated rat hepatocytes J Lipid Res 28 1987 152 161
    • (1987) J Lipid Res , vol.28 , pp. 152-161
    • Cighetti, G.1    Delpuppo, M.2    Paroni, R.3    Fiorica, E.4    Kienle, M.5
  • 42
    • 0019988231 scopus 로고
    • Effect of pantethine on the biosynthesis of cholesterol in human skin fibroblasts
    • S. Ranganathan, R. Jackson, and J. Harmony Effect of pantethine on the biosynthesis of cholesterol in human skin fibroblasts Atherosclerosis 44 1982 261 273
    • (1982) Atherosclerosis , vol.44 , pp. 261-273
    • Ranganathan, S.1    Jackson, R.2    Harmony, J.3
  • 43
    • 0020047026 scopus 로고
    • Effect of pantethine on lipoprotein profiles and HDL subfractions in experimentally hypercholesterolemic rabbits
    • M. Tomikawa, T. Nakayasu, K. Tawara, K. Kameda, and Y. Abiko Effect of pantethine on lipoprotein profiles and HDL subfractions in experimentally hypercholesterolemic rabbits Atherocsclerosis 41 1982 267 277
    • (1982) Atherocsclerosis , vol.41 , pp. 267-277
    • Tomikawa, M.1    Nakayasu, T.2    Tawara, K.3    Kameda, K.4    Abiko, Y.5
  • 45
    • 0021750852 scopus 로고
    • Pantethine reduces plasma cholesterol and the severity of arterial lesions in experimental hypercholesterolemic rabbits
    • P. Carrara, L. Matturri, M. Galbussera, M. Lovati, G. Franceschini, and C. Sirtori Pantethine reduces plasma cholesterol and the severity of arterial lesions in experimental hypercholesterolemic rabbits Atherosclerosis 53 1984 255 264
    • (1984) Atherosclerosis , vol.53 , pp. 255-264
    • Carrara, P.1    Matturri, L.2    Galbussera, M.3    Lovati, M.4    Franceschini, G.5    Sirtori, C.6
  • 46
    • 0021971372 scopus 로고
    • Effects of pantethine on in-vitro peroxidation of low density lipoproteins
    • G. Bon, G. Cazzolato, S. Zago, and P. Avogaro Effects of pantethine on in-vitro peroxidation of low density lipoproteins Atherosclerosis 57 1985 99 106
    • (1985) Atherosclerosis , vol.57 , pp. 99-106
    • Bon, G.1    Cazzolato, G.2    Zago, S.3    Avogaro, P.4
  • 48
    • 0035040875 scopus 로고    scopus 로고
    • Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine
    • M. McCarty Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine Med Hypotheses 56 2001 314 317
    • (2001) Med Hypotheses , vol.56 , pp. 314-317
    • McCarty, M.1
  • 49
    • 0024981839 scopus 로고
    • Pantetina, diabete e aterosclerosi: Indagine clinica su 1045 pazienti
    • C. Donati, R. Bertieri, and G. Barbi Pantetina, diabete e aterosclerosi: indagine clinica su 1045 pazienti Clin Ther 128 1989 411 422
    • (1989) Clin Ther , vol.128 , pp. 411-422
    • Donati, C.1    Bertieri, R.2    Barbi, G.3
  • 50
    • 0031938673 scopus 로고    scopus 로고
    • Overview of fenofibrate
    • C. Packard Overview of fenofibrate Eur Heart J 19 Suppl. A 1998 a62 a65
    • (1998) Eur Heart J , vol.19 , Issue.SUPPL. A
    • Packard, C.1
  • 51
    • 0027315508 scopus 로고
    • Literature review on fenofibrate
    • M. Triguero Literature review on fenofibrate An Med Interna 10 1993 195 199
    • (1993) An Med Interna , vol.10 , pp. 195-199
    • Triguero, M.1
  • 52
    • 0025128458 scopus 로고
    • Fenofibrate: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in dyslipidaemia
    • J. Balfour, D. McTavish, and R. Heel Fenofibrate: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in dyslipidaemia Drugs 40 1990 260 290
    • (1990) Drugs , vol.40 , pp. 260-290
    • Balfour, J.1    McTavish, D.2    Heel, R.3
  • 53
    • 0029825461 scopus 로고    scopus 로고
    • Bezafibrate. An update of its pharmacology and use in the management of dyslipidaemia
    • K. Goa, L. Barradell, and G. Plosker Bezafibrate. An update of its pharmacology and use in the management of dyslipidaemia Drugs 52 1996 725 753
    • (1996) Drugs , vol.52 , pp. 725-753
    • Goa, K.1    Barradell, L.2    Plosker, G.3
  • 54
    • 0025272920 scopus 로고
    • Therapy of hypercholesterolemia and hypertriglyceridemia: Comparison of the lipid-lowering effect of simvastatin and tiadenol
    • T. Serra, M. Gavelii, E. Vitaliano, G. Santini, A. Catalano, and F. Rossi Therapy of hypercholesterolemia and hypertriglyceridemia: comparison of the lipid-lowering effect of simvastatin and tiadenol Clin Ther 132 1990 307 313
    • (1990) Clin Ther , vol.132 , pp. 307-313
    • Serra, T.1    Gavelii, M.2    Vitaliano, E.3    Santini, G.4    Catalano, A.5    Rossi, F.6
  • 55
    • 0037387192 scopus 로고    scopus 로고
    • Sustained reduction of serum cholesterol in low-dose 6-year simvastatin treatment with minimum side effects in 51,321 Japanese hypercholesterolemic patients
    • Y. Matsuzawa, T. Kita, H. Mabuchi, M. Matsuzaki, N. Nakaya, and S. Oikawa Sustained reduction of serum cholesterol in low-dose 6-year simvastatin treatment with minimum side effects in 51,321 Japanese hypercholesterolemic patients Circ J 67 2003 287 294
    • (2003) Circ J , vol.67 , pp. 287-294
    • Matsuzawa, Y.1    Kita, T.2    Mabuchi, H.3    Matsuzaki, M.4    Nakaya, N.5    Oikawa, S.6


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