메뉴 건너뛰기




Volumn 22, Issue 24, 2004, Pages 4944-4950

Gemcitabine and ISIS-2503 for patients with locally advanced or metastatic pancreatic adenocarcinoma: A North Central Cancer Treatment Group phase II trial

Author keywords

[No Author keywords available]

Indexed keywords

GEMCITABINE; ISIS 2503; ANTINEOPLASTIC ANTIMETABOLITE; ANTISENSE OLIGONUCLEOTIDE; DEOXYCYTIDINE; DRUG DERIVATIVE;

EID: 16644402183     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2004.05.034     Document Type: Article
Times cited : (88)

References (18)
  • 2
    • 0031718102 scopus 로고    scopus 로고
    • Resection of pancreatic cancer-surgical achievements
    • Trede M, Saeger HD, Schwall G, et al: Resection of pancreatic cancer-surgical achievements. Langenbecks Arch Surg 383:121-1288, 1998
    • (1998) Langenbecks Arch Surg , vol.383 , pp. 121-1288
    • Trede, M.1    Saeger, H.D.2    Schwall, G.3
  • 3
    • 84944367593 scopus 로고
    • A comparison of three chemotherapeutic regimens in the treatment of advanced pancreatic and gastric carcinoma. Fluorouracil vs fluorouracil and doxorubicin vs fluorouracil, doxorubicin, and mitomycin
    • Cullinan SA, Moertel CG, Fleming TR, et al: A comparison of three chemotherapeutic regimens in the treatment of advanced pancreatic and gastric carcinoma. Fluorouracil vs fluorouracil and doxorubicin vs fluorouracil, doxorubicin, and mitomycin. JAMA 253:2061-2067, 1985
    • (1985) JAMA , vol.253 , pp. 2061-2067
    • Cullinan, S.A.1    Moertel, C.G.2    Fleming, T.R.3
  • 4
    • 0025841867 scopus 로고
    • Fluorouracil and high-dose leucovorin in previously untreated patients with advanced adenocarcinoma of the pancreas: Results of a phase II trial
    • DeCaprio JA, Mayer RJ, Gonin R, et al: Fluorouracil and high-dose leucovorin in previously untreated patients with advanced adenocarcinoma of the pancreas: Results of a phase II trial. J Clin Oncol 9:2128-2133, 1991
    • (1991) J Clin Oncol , vol.9 , pp. 2128-2133
    • DeCaprio, J.A.1    Mayer, R.J.2    Gonin, R.3
  • 5
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA 3rd, Moore MJ, Andersen J, et al: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial. J Clin Oncol 15:2403-2413, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris 3rd, H.A.1    Moore, M.J.2    Andersen, J.3
  • 7
    • 0345363003 scopus 로고    scopus 로고
    • Ras proteins: Recent advances and new functions
    • Rebollo A, Martinez AC: Ras proteins: Recent advances and new functions. Blood 94:2971-2980, 1999
    • (1999) Blood , vol.94 , pp. 2971-2980
    • Rebollo, A.1    Martinez, A.C.2
  • 8
    • 0033026035 scopus 로고    scopus 로고
    • Transforming growth factor alpha activates Ha-Ras in human pancreatic cancer cells with Ki-ras mutations
    • Seufferlein T, Van Lint J, Liptay S, et al: Transforming growth factor alpha activates Ha-Ras in human pancreatic cancer cells with Ki-ras mutations. Gastroenterology 116:1441-1452, 1999
    • (1999) Gastroenterology , vol.116 , pp. 1441-1452
    • Seufferlein, T.1    Van Lint, J.2    Liptay, S.3
  • 9
    • 0030797704 scopus 로고    scopus 로고
    • Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides
    • Geary RS, Leeds JM, Henry SP, et al: Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides. Anticancer Drug Des 12:383-393, 1997
    • (1997) Anticancer Drug Des , vol.12 , pp. 383-393
    • Geary, R.S.1    Leeds, J.M.2    Henry, S.P.3
  • 10
    • 0026774939 scopus 로고
    • Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides
    • Monia BP, Johnston JF, Ecker DJ, et al: Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides. J Biol Chem 267:19954-19962, 1992
    • (1992) J Biol Chem , vol.267 , pp. 19954-19962
    • Monia, B.P.1    Johnston, J.F.2    Ecker, D.J.3
  • 11
    • 12244260756 scopus 로고    scopus 로고
    • A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer
    • Adjei AA, Dy GK, Erlichman C, et al: A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer. Clin Cancer Res 9:115-123, 2003
    • (2003) Clin Cancer Res , vol.9 , pp. 115-123
    • Adjei, A.A.1    Dy, G.K.2    Erlichman, C.3
  • 12
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • Therasse P, Arbuck SG, Eisenhauer EA, et al: New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 92:205-216, 2000
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 13
    • 0020108590 scopus 로고
    • One sample multiple testing procedure for phase II clinical trials
    • Fleming TR: One sample multiple testing procedure for phase II clinical trials. Biometrics 38:143-151, 1982
    • (1982) Biometrics , vol.38 , pp. 143-151
    • Fleming, T.R.1
  • 14
    • 0023176979 scopus 로고
    • Confidence intervals for a binomial parameter based on multistage tests
    • Duffy D, Santner T: Confidence intervals for a binomial parameter based on multistage tests. Biometrics 43:81-93, 1987
    • (1987) Biometrics , vol.43 , pp. 81-93
    • Duffy, D.1    Santner, T.2
  • 15
    • 33845382806 scopus 로고
    • Nonparametric estimation for incomplete observations
    • Kaplan E, Meier P: Nonparametric estimation for incomplete observations. J Am Stat Assoc 53:457-481, 1958
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 16
    • 0038413837 scopus 로고    scopus 로고
    • Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma
    • Cohen SJ, Ho L, Ranganathan S, et al: Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma. J Clin Oncol 21:1301-1306, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 1301-1306
    • Cohen, S.J.1    Ho, L.2    Ranganathan, S.3
  • 17
    • 0000324578 scopus 로고    scopus 로고
    • Phase III trial comparing gemcitabine + R115777 (Zarnestra) versus gemcitabine + placebo in advanced pancreatic cancer (PC)
    • abstr 517
    • Van Cutsem E, Oettle K, Vervenne W, et al: Phase III trial comparing gemcitabine + R115777 (Zarnestra) versus gemcitabine + placebo in advanced pancreatic cancer (PC). Proc Am Soc Clin Oncol 21:130a, 2002 (abstr 517)
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Van Cutsem, E.1    Oettle, K.2    Vervenne, W.3
  • 18
    • 0035447768 scopus 로고    scopus 로고
    • A Phase I trial of H-ras antisense oligonucleotide ISIS 2503 administered as a continuous intravenous infusion in patients with advanced carcinoma
    • Cunningham CC, Holmlund JT, Geary RS, et al: A Phase I trial of H-ras antisense oligonucleotide ISIS 2503 administered as a continuous intravenous infusion in patients with advanced carcinoma. Cancer 92:1265-1271, 2001
    • (2001) Cancer , vol.92 , pp. 1265-1271
    • Cunningham, C.C.1    Holmlund, J.T.2    Geary, R.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.