The use of antibodies to coagulant factors for anticoagulant therapy

Current Medicinal Chemistry

Volumn 11, Issue 17, 2004, Pages 2291-2296

  Jacquemin, Marc ^a   Saint Remy, J M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Anticoagulant; Factor IX; Factor VIII; Monoclonal antibody; Tissue factor

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 ANTIBODY; BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9 ANTIBODY; BLOOD CLOTTING FACTOR 9A ANTIBODY; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY D3H44; MONOCLONAL ANTIBODY LE2E9; PROTEIN ANTIBODY; SB 249417; THROMBOPLASTIN; THROMBOPLASTIN ANTIBODY; UNCLASSIFIED DRUG; THROMBIN;

ANTICOAGULANT THERAPY; ANTICOAGULATION; BLEEDING; CANCER; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; DEEP VEIN THROMBOSIS; DRUG ACTIVITY; DRUG HALF LIFE; DRUG SPECIFICITY; DRUG TARGETING; HUMAN; IN VIVO STUDY; NONHUMAN; REVIEW; THROMBOSIS; ANIMAL; BINDING SITE; BLOOD CLOTTING; CHEMISTRY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; NEOPLASM;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTICOAGULANTS; BINDING SITES; BLOOD COAGULATION; BLOOD COAGULATION FACTORS; CARDIOVASCULAR DISEASES; DISEASE MODELS, ANIMAL; HUMANS; NEOPLASMS; THROMBIN; THROMBOSIS;

EID: 16644401173     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867043364612     Document Type: Review

References (66)

1. Research Committee of the British Thoracic Society. Lancet, 1992, 340, 873.
2. Hylek, E.M.; Singer, D.E. Ann. Intern. Med., 1994, 120, 897.
3. Cannegieter, S.C.; Rosendaal, F.R.; Wintzen, A.R.; van der Meer, F.J.; Vandenbroucke, J.P.; Briet, E. N. Engl. J. Med. 1995, 333, 11.
4. Khazaeli, M.B.; Saleh, M.N.; Liu, T.; Kaladas, P.M.; Gilman, S.C.; LoBuglio, A.F.J. Clin. Immunol., 1992, 12, 116.
5. Weinblatt, M.E.; Maddison, P.J.; Bulpitt, K.J.; Hazleman, B.L.; Urowitz, M.B.; Sturrock, R.D.; Coblyn, J.S.; Maier, A.L.; Spreen, W.R.; Manna, V.K. Arthritis Rheum., 1995, 38, 1589.
6. Harries, M.; Smith, I. Endocr. Relat. Cancer, 2002, 9, 75.
7. Jaeger, G.; Neumeister, P.; Brezinschek, R.; Hofler, G.; Quehenberger, F.; Linkesch, W.; Sill, H. Eur. J. Haematol., 2002, 69, 21.
8. Ghosh, S. Expert Opin. Biol. Ther., 2003, 3, 995.
9. Milgrom, H, Fick, RB, Su, JQ, Reimann, JD, Bush, RK, Watrous, ML et al. N. Engl. J. Med. 1999, 26, 1966.
10. Boushey, H.A. J. Allergy Clin. Immunol., 2001, 108, S77.
11. Wilcox, J.N.; Smith, K.M.; Schwartz, S.M.; Gordon, D. Proc. Natl. Acad. Sci. USA, 1989, 86, 2839.
12. Giesen, P.L., Rauch, U.; Bohrmann, B.; Kling, D.; Roque, M.; Fallon, J.T.; Badimon, J.J.; Himber, J.; Riederer, M.A.; Nemerson, Y. Proc. Natl. Acad. Sci. USA, 1999, 96, 2311.
13. Falati, S.; Gross, P.; Merrill-Skoloff, G.; Furie, B.C. Furie B. Nat. Med., 2002, 8, 1175.
14. Balasubramanian, V.; Grabowski , E.; Bini, A.; Nemerson, Y. Blood, 2002, 100, 2787.
15. Zhang, Y.; Deng, Y.; Luther, T.; Muller, M.; Ziegler, R.; Waldherr, R.; Stern, D.M.; Nawroth P.P. J. Clin. Invest., 1994; 94:1320.
16. Contrino, J.; Hair, G.; Kreutzer, D.L.; Rickles, F.R. Nat. Med., 1996, 2, 209.
17. Taylor, F.B. Jr.; Chang, A.; Ruf, W.; Morrissey, J.H.; Hinshaw, L.; Catlett, R.; Blick, K.; Edgington, T.S. Circ. Shock., 1991, 33, 127.
18. Riewald, M.; Ruf, W. Trends Cardiovasc. Med., 2002, 12, 149.
19. Petersen, L.C.; Freskgard, P; Ezban, M., 2000, 10, 47.
20. Carson, S.D.; Bach, R.; Carson, S.M. Blood, 1985, 66, 152.
21. Morrissey, J.H.; Fair, D.S.; Edgington, T.S. Thromb. Res., 1988, 52, 247.
22. Ruf, W.; Edgington, T.S. Thromb. Haemost., 1991, 66, 529.
23. Ruf, W.; Shobe, J.; Rao, S.M.; Dickinson, C.D.; Olson, A.; Edgington, T.S. Biochemistry, 1999, 38, 1957.
24. Ito, T.; Hiraiwa, J.; Nishioka, J.; Iino, M.; Suzuki, K. J. Biochem., 1993, 114, 691.
25. Kirchhofer, D.; Moran, P.; Chiang, N.; Kim, J.; Riederer, M.A.; Eigenbrot, C.; Kelley, R.F. Thromb. Haemost., 2000, 84, 1072.
26. Huang, M.; Syed, R.; Stura, E.A.; Stone, M.J.; Stefanko, R.S.; Ruf, W.; Edgington, T.S.; Wilson, I.A. J. Mol. Biol., 1998, 275, 873.
27. Pawashe, A.B.; Golino, P.; Ambrosio, G; Migliaccio, F; Ragni, M; Pascucci, I; Chiariello, M; Bach, R; Garen, A; Konigsberg, WK; Ezekowitz, M.D. Circ. Res., 1994, 74, 56.
28. Ragni, M.; Cirillo, P.; Pascucci, I.; Scognamiglio, A.; D'Andrea, D.; Eramo, N.; Ezekowitz, M.D.; Pawashe, A.B.; Chiariello, M., Golino, P. Circulation, 1996, 93, 1913.
29. Jang, I.K.; Gold, H.K; Leinbach, R.C.; Fallon, J.T.; Collen, D.; Wilcox, J.N.. Arterioscler. Thromb., 1992, 12, 948.
30. Presta, L.; Sims, P; Meng, Y.G.; Moran, P.; Bullens, S.; Bunting, S.; Schoenfeld, J.; Lowe, D.; Lai, J; Rancatore, P.; Iverson, M.; Lim, A.; Chisholm, V.; Kelley, R.F.; Riederer, M.; Kirchhofer, D. Thromb. Haemost., 2001, 85, 379.
31. Huang, Q. Neuenschwander, P.F.; Rezaie, A.R.; Morrissey, J.H. J. Biol. Chem., 1996, 271, 21752.
32. Zhong, D.; Bajaj, M.S.; Schmidt, A.E.; Bajaj, S.P. J. Biol. Chem., 2002, 277, 3622.
33. Harker, L.A.; Hanson, S.R.; Wilcox, J.N.; Kelly, A.B. Haemostasis, 1996, 26 Suppl 1, 76.
34. Bullens, S.; Smith, N.; Rowell, T.J.; Chen, C.; Hanson, S.; Bunting, S.. Thromb. Haemost. (Suppl.), 2001 abstract #P1388
35. Eigenbrot, C.; Meng, Y.G.; Krishnamurthy, R.; Lipari, M.T.; Presta, L.; Devaux, B.; Wong, T.; Moran, P.; Bullens, S.; Kirchhofer, D. J. Mol. Biol., 2003, 331, 433.
36. Lollar, P.; Fass, D.N. Arch. Biochem. Biophys. 1984, 233, 438.
37. Benedict, C.R.; Ryan, J.; Wolitzky, B.; Ramos, R.; Gerlach, M.; Tijburg, P.; Stern, D. J. Clin. Invest., 1991, 88, 1760.
38. Feuerstein, G.Z.; Patel, A.; Toomey, J.R.; Bugelski, P.; Nichols, A.J.; Church, W.R.; Valocik, R.; Koster, P.; Baker, A.; Blackburn, M.N. Arterioscler. Thromb. Vasc. Biol., 1999, 19, 2554.
39. Refino, C.J.; Himber, J.; Burcklen, L.; Moran, P.; Peek, M.; Suggett, S.; Devaux, B.; Kirchhofer, D. Thromb. Haemost., 1999, 82, 1188.
40. Hovig, T.; Dodds, W.J.; Rowsell, H.C.; Mustard, J.F. Am. J. Pathol. 1968, 53, 355.
41. Sixma, J.J.; van den Berg, A. Br. J. Haematol., 1984, 58, 741.
42. Smokovitis, A.; Astrup, T. J. Invest. Dermatol., 1978, 70, 321.
43. Benincosa, L.J; Chow, F.S.; Tobia, L.P.; Kwok, D.C.; Davis, C.B.; Jusko, W.J. J. Pharmacol. Exp. Ther., 2000, 292, 810.
44. Hathaway, W.E.; Assmus, S.L.; Montgomery, R.R.; Dubansky, A.S. Am. J. Clin. Pathol., 1979, 71, 22.
45. Hoffmann, J.J.; Meulendijk, P.N. Thromb. Haemost., 1978, 39, 640.
46. Toomey, J.R.; Valocik, R.E.; Koster, P.F.; Gabriel, M.A.; McVey, M.; Hart, T.K.; Ohlstein, E.H.; Parsons, A.A.; Barone, F.C. Stroke, 2002, 33, 578.
47. Choudhri, T.F.; Hoh, B.L.; Prestigiacomo, CJ.; Huang, J.; Kim, L.J.; Schmidt, A.M.; Kisiel, W.; Connolly, E.S. Jr.; Pinsky, D.J. J. Exp. Med., 1999, 190, 91.
48. Chow, F.S.; Benincosa, L.J.; Sheth, S.B.; Wilson, D.; Davis, C.B.; Minthorn, E.A.; Jusko, W.J. Clin. Pharmacol. Ther., 2002, 71, 235.
49. Zia-Amirhosseini, P.; Minthorn, E.; Benincosa, L.J.; Hart T.K.; Hottenstein, C.S.; Tobia, L.A.; Davis, C.B. J. Pharmacol. Esp. Ther., 1999, 291:1060.
50. Davis, C.B.; Tobia, L.P.; Kwok, D.C.; Oishi, C.M.; Kheterpal, N.; Hepburn, T.W.; Benincosa, L.J.; Chow, F.; Jusko, W.J. Drug Delivery, 1999, 6, 171.
51. Stewart, A.J.; Manson, L.M.; Dennis, R.; Allan, P.L.; Ludlam, C.A. Hemophilia, 2000, 6, 47.
52. Sramek, A.; Kriek, M.; Rosendaal, FR Lancet, 2003, 362, 351.
53. Koster, T.; Blann, A.D.; Briet, E.; Vandenbroucke, J.P.; Rosendaal, F.R. Lancet, 1995, 345, 152.
54. Kyrle, P.A.; Minar, E.; Hirschl, M.; Bialonczyk, C.; Stain, M.; Schneider, B.; Weltermann, A.; Speiser, W.; Lechner, K.; Eichinger, S. N. Engl. J. Med., 2000, 343, 457.
55. O'Donnell, J.; Mumford, A.D.; Manning, R.A.; Laffan, M. Thromb. Haemost., 2000, 83, 10.
56. Kraaijenhagen, R.A.; in't Anker, P.S.; Koopman, M.M.; Reitsma, P.H.; Prins, M.H.; van den Ende, A.; Buller HR. Thromb. Haemost., 2000, 83, 5.
57. Egeberg, O. Scand. J. Clin. Lab. Invest., 1962, 14, 253.
58. Rumley, A.; Lowe, G.D.; Sweetnam PM, Yarnell, J.W.G.; Fordm R.P. Br. J. Haematol., 1999, 105, 110.
59. Tracy, R.P.; Arnold, A.M.; Ettinger, W.; Fried, L.; Meilahn, E.; Savage, P. Arterioscler. Thromb. Vasc. Biol., 1999, 19, 1776.
60. Folsom, A.R.; Wu, K.K.; Rosamond, W.D.; Sharrett, A.R.; Chambless, L.E. Circulation, 1997, 96, 1102.
61. Jones, P.K.; Ratnoff, O.D. Ann. Intern. Med. 1991, 114, 641.
62. Jacquemin, M.; Benhida, A.; Peerlinck, K.; Desqueper, B; Vander Elst, L.; Lavend'homme, R.; d'Oiron, R.; Schwaab, R.; Bakkus, M.; Thielemans, K.; Gilles, J.G.; Vermylen, J.; Saint-Remy, J.M. Blood, 2000, 95, 156.
63. Dewerchin, M.; Van der Elst, L.; Singh, I.; Grailly, S.; Saint-Remy, J.M.; Collen, D; Jacquemin, M. J. Thromb. Haemost., 2004, 2, 77.
64. Singh, I.; Smith, A.; Vanzieleghem, B.; Collen, D.; Burnand, K.; Saint-Remy J.M.; Jacquemin, M. Blood, 2002, 99, 3235.
65. Dewerchin, M.; Hérault, J.P.; Wallays, G.; Petitou, M.; Schaeffer, P.; Millet, L.; Weitz, J.I.; Moons, L.; Collen, D.; Carmeliet, P.; Herbert, J.M. Circ. Res., in press.
66. Morell, A.; Terry, W.D.; Waldmann, T.A. J. Clin. Invest., 1970, 49, 673.