메뉴 건너뛰기




Volumn 19, Issue 9, 2004, Pages 1518-1524

Raloxifene treatment is associated with increased serum estradiol and decreased bone remodeling in healthy middle-aged men with low sex hormone levels

Author keywords

Bone; Males; Osteoporosis; Selective estrogen receptor modulators; Sex hormones

Indexed keywords

ALKALINE PHOSPHATASE; BIOCHEMICAL MARKER; CREATININE; DEOXYPYRIDINOLINE; ESTRADIOL; OSTEOCALCIN; PLACEBO; RALOXIFENE; SEX HORMONE; TESTOSTERONE; AMINO ACID; BIOLOGICAL MARKER; CREATINE;

EID: 16644396733     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.040503     Document Type: Article
Times cited : (57)

References (27)
  • 3
    • 0035985846 scopus 로고    scopus 로고
    • Raloxifene: Recent information on skeletal and non-skeletal effects
    • Gluck O, Maricic M 2002 Raloxifene: Recent information on skeletal and non-skeletal effects. Curr Opin Rheumatol 14:429-432.
    • (2002) Curr Opin Rheumatol , vol.14 , pp. 429-432
    • Gluck, O.1    Maricic, M.2
  • 4
    • 0034778526 scopus 로고    scopus 로고
    • Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men
    • Doran PM, Riggs BL, Atkinson EJ, Khosla S 2001 Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men. J Bone Miner Res 16:2118-2125.
    • (2001) J Bone Miner Res , vol.16 , pp. 2118-2125
    • Doran, P.M.1    Riggs, B.L.2    Atkinson, E.J.3    Khosla, S.4
  • 7
    • 0028792229 scopus 로고
    • Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens
    • Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K 1995 Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab 80:3689-3698.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3689-3698
    • Morishima, A.1    Grumbach, M.M.2    Simpson, E.R.3    Fisher, C.4    Qin, K.5
  • 8
    • 0032572929 scopus 로고    scopus 로고
    • Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency
    • Bilezikian JP, Morishima A, Bell J, Grumbach MM 1998 Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency. N Engl J Med 339:599-603.
    • (1998) N Engl J Med , vol.339 , pp. 599-603
    • Bilezikian, J.P.1    Morishima, A.2    Bell, J.3    Grumbach, M.M.4
  • 10
    • 0030931083 scopus 로고    scopus 로고
    • Sex steroids and bone mass in older men. Positive associations with serum estrogens and negative associations with androgens
    • Slemenda CW, Longcope C, Zhou L, Hui SL, Peacock M, Johnston CC 1997 Sex steroids and bone mass in older men. Positive associations with serum estrogens and negative associations with androgens. J Clin Invest 100:1755-1759.
    • (1997) J Clin Invest , vol.100 , pp. 1755-1759
    • Slemenda, C.W.1    Longcope, C.2    Zhou, L.3    Hui, S.L.4    Peacock, M.5    Johnston, C.C.6
  • 11
    • 0030685090 scopus 로고    scopus 로고
    • Endogenous sex steroids and bone mineral density in older women and men: The Rancho Bemardo Study
    • Greendale GA, Edelstein S, Barrett-Connor E 1997 Endogenous sex steroids and bone mineral density in older women and men: The Rancho Bemardo Study. J Bone Miner Res 12:1833-1843.
    • (1997) J Bone Miner Res , vol.12 , pp. 1833-1843
    • Greendale, G.A.1    Edelstein, S.2    Barrett-Connor, E.3
  • 12
    • 0031756218 scopus 로고    scopus 로고
    • Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: A key role for bioavailable estrogen
    • Khosla S, Melton LJ III, Atkinson EJ, O'Fallon WM, Klee GG, Riggs BL 1998 Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: A key role for bioavailable estrogen. J Clin Endocrinol Metab 83:2266-2274.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2266-2274
    • Khosla, S.1    Melton III, L.J.2    Atkinson, E.J.3    O'Fallon, W.M.4    Klee, G.G.5    Riggs, B.L.6
  • 13
    • 0033304569 scopus 로고    scopus 로고
    • Hormonal and biochemical parameters in the determination of osteoporosis in elderly men
    • Center JR, Nguyen TV, Sambrook PN, Eisman JA 1999 Hormonal and biochemical parameters in the determination of osteoporosis in elderly men. J Clin Endocrinol Metab 84:3626-3635.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3626-3635
    • Center, J.R.1    Nguyen, T.V.2    Sambrook, P.N.3    Eisman, J.A.4
  • 14
    • 0033678650 scopus 로고    scopus 로고
    • Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men
    • van den Beld AW, de Jong FH, Grobbee DE, Pols HA, Lamberts SW 2000 Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men. J Clin Endocrinol Metab 85:3276-3282.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3276-3282
    • Van Den Beld, A.W.1    De Jong, F.H.2    Grobbee, D.E.3    Pols, H.A.4    Lamberts, S.W.5
  • 16
    • 0034890081 scopus 로고    scopus 로고
    • Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men
    • Khosla S, Melton LJ III, Atkinson EJ, O'Fallon WM 2001 Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men. J Clin Endocrinol Metab 86:3555-3561.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3555-3561
    • Khosla, S.1    Melton III, L.J.2    Atkinson, E.J.3    O'Fallon, W.M.4
  • 18
    • 0034970468 scopus 로고    scopus 로고
    • The effect of aromatase inhibition on sex steroids, gonadotropins, and markers of bone turnover in older men
    • Taxel P, Kennedy DG, Fall PM, Willard AK, Clive JM, Raisz LG 2001 The effect of aromatase inhibition on sex steroids, gonadotropins, and markers of bone turnover in older men. J Clin Endocrinol Metab 86:2869-2874.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2869-2874
    • Taxel, P.1    Kennedy, D.G.2    Fall, P.M.3    Willard, A.K.4    Clive, J.M.5    Raisz, L.G.6
  • 19
    • 0034521393 scopus 로고    scopus 로고
    • Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men
    • Falahati-Nini A, Riggs BL, Atkinson EJ, O'Fallon WM, Eastell R, Khosla S 2000 Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest 106:1553-1560.
    • (2000) J Clin Invest , vol.106 , pp. 1553-1560
    • Falahati-Nini, A.1    Riggs, B.L.2    Atkinson, E.J.3    O'Fallon, W.M.4    Eastell, R.5    Khosla, S.6
  • 20
    • 0033305020 scopus 로고    scopus 로고
    • A critical evaluation of simple methods for the estimation of free testosterone in serum
    • Vermeulen A, Verdonck L, Kaufman JM 1999 A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 84:3666-3672.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3666-3672
    • Vermeulen, A.1    Verdonck, L.2    Kaufman, J.M.3
  • 21
    • 0032542897 scopus 로고    scopus 로고
    • What's wrong with Bonferroni adjustments
    • Perneger TV 1998 What's wrong with Bonferroni adjustments. BMJ 316:1236-1238.
    • (1998) BMJ , vol.316 , pp. 1236-1238
    • Perneger, T.V.1
  • 22
    • 0030015080 scopus 로고    scopus 로고
    • A controlled trial of raloxifene (LY139481) HCl: Impact on bone turnover and serum lipid profile in healthy postmenopausal women
    • Draper MW, Flowers DE, Huster WJ, Neild JA, Harper KD, Arnaud C 1996 A controlled trial of raloxifene (LY139481) HCl: Impact on bone turnover and serum lipid profile in healthy postmenopausal women. J Bone Miner Res 11:835-842.
    • (1996) J Bone Miner Res , vol.11 , pp. 835-842
    • Draper, M.W.1    Flowers, D.E.2    Huster, W.J.3    Neild, J.A.4    Harper, K.D.5    Arnaud, C.6
  • 23
  • 25
    • 0031790699 scopus 로고    scopus 로고
    • Reproductive endocrine and endometrial effects of raloxifene hydrochloride, a selective estrogen receptor modulator, in women with regular menstrual cycles
    • Baker VL, Draper M, Paul S, Allerheiligen S, Glant M, Shifren J, Jaffe RB 1998 Reproductive endocrine and endometrial effects of raloxifene hydrochloride, a selective estrogen receptor modulator, in women with regular menstrual cycles. J Clin Endocrinol Metab 83:6-13.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 6-13
    • Baker, V.L.1    Draper, M.2    Paul, S.3    Allerheiligen, S.4    Glant, M.5    Shifren, J.6    Jaffe, R.B.7
  • 27
    • 0037045446 scopus 로고    scopus 로고
    • Serum estradiol level and risk of breast cancer during treatment with raloxifene
    • Cummings SR, Duong T, Kenyon E, Cauley JA, Whitehead M, Krueger KA 2002 Serum estradiol level and risk of breast cancer during treatment with raloxifene. JAMA 287:216-220.
    • (2002) JAMA , vol.287 , pp. 216-220
    • Cummings, S.R.1    Duong, T.2    Kenyon, E.3    Cauley, J.A.4    Whitehead, M.5    Krueger, K.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.