Intermittent ibandronate preserves bone quality and bone strength in the lumbar spine after 16 months of treatment in the ovariectomized cynomolgus monkey

Journal of Bone and Mineral Research

Volumn 19, Issue 11, 2004, Pages 1787-1796

  Müller, Ralph ^a,e   Hannan, Mary ^a   Smith, Susan Y ^b   Bauss, Frieder ^c,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CTBR Bio Research Inc (CTBR)   (Canada)

^c ROCHE DIAGNOSTICS GMBH   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

CT; Bisphosphonate treatment; Bone quality; Bone strength; Non human primates

Indexed keywords

IBANDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; DNA;

ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BOLUS INJECTION; BONE DENSITOMETRY; BONE MASS; BONE STRENGTH; BONE STRESS; BONE STRUCTURE; BONE TISSUE; BONE TURNOVER; CERVICAL SPINE RADIOGRAPHY; COMPRESSIVE STRENGTH; CONTROLLED STUDY; DOSE CALCULATION; DOSE TIME EFFECT RELATION; DRUG DOSE REGIMEN; DRUG EFFECT; FEMALE; LINEAR REGRESSION ANALYSIS; LUMBAR SPINE; LUMBAR VERTEBRA; MACACA; MEDICAL ASSESSMENT; MORPHOMETRICS; NONHUMAN; OSTEOLYSIS; OVARIECTOMY; PREDICTION; SHAM FEEDING; THREE DIMENSIONAL IMAGING; ANIMAL; BACK; BONE; BONE DENSITY; BONE REMODELING; COMPUTER ASSISTED TOMOGRAPHY; DENSITOMETRY; DOSE RESPONSE; METABOLISM; OSTEOPOROSIS; OVARY; PATHOLOGY; PHYSIOLOGY; SPINE; STATISTICAL MODEL; TENSILE STRENGTH; TIME;

ANIMALS; BONE AND BONES; BONE DENSITY; BONE REMODELING; BONE RESORPTION; DENSITOMETRY; DIPHOSPHONATES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LINEAR MODELS; LUMBAR VERTEBRAE; LUMBOSACRAL REGION; MACACA FASCICULARIS; OSTEOPOROSIS; OVARIECTOMY; OVARY; SPINE; TENSILE STRENGTH; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 16644393178     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.040809     Document Type: Article

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