Serum protein fingerprinting coupled with artificial neural network distinguishes glioma from healthy population or brain benign tumor

Journal of Zhejiang University: Science B

Volumn 6, Issue 1, 2005, Pages 4-10

  Liu, Jian ^a   Zheng, Shu ^a   Yu, Jie kai ^a   Zhang, Jian min ^a   Chen, Zhe ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Artificial Neural Network (ANN); Astrocytoma; Diagnosis; Protein fingerprint; R739.41; SELDI TOF MS

Indexed keywords

TUMOR MARKER; TUMOR PROTEIN;

ADULT; AGED; ALGORITHM; ARTIFICIAL INTELLIGENCE; ARTIFICIAL NEURAL NETWORK; ASTROCYTOMA; BLOOD; BRAIN TUMOR; CLASSIFICATION; CLINICAL TRIAL; COMPARATIVE STUDY; COMPUTER ASSISTED DIAGNOSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LETTER; MALE; MASS SPECTROMETRY; METHODOLOGY; MIDDLE AGED; PEPTIDE MAPPING; PROTEIN MICROARRAY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

ADULT; AGED; ALGORITHMS; ARTIFICIAL INTELLIGENCE; ASTROCYTOMA; BRAIN NEOPLASMS; DIAGNOSIS, COMPUTER-ASSISTED; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; NEURAL NETWORKS (COMPUTER); PEPTIDE MAPPING; PROTEIN ARRAY ANALYSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TUMOR MARKERS, BIOLOGICAL;

MLCS; MLOWN;

EID: 16644377301     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.2005.B0004     Document Type: Article

References (13)

1. Ball, G., Mian, S., Holding, F., Allibone, R.O., Lowe, J., Ali, S., Li, G., Mccardle, S., ElLis, I.Q., Creaser, C., Rees, R.C., 2002. An integrated approach utilizing artificial neural networks and SELDI mass spectrometry for the classification of human tumours and rapid identification of potential biomarkers.Bioinformatics,18(3):395–404. DOI: 10.1093/bioinformatics/18.3.395
2. Bast, R.C.Jr., 2003. Status of tumor markers in ovarian cancer screening.J Clin Oncol,21(10 Suppl):200–205. DOI: 10.1200/JCO.2003.01.068
3. Cazares, L.H., Adam, B.L., Ward, M.D., Nasim, S., Schellhammer, P.F., Semmes, O.J., Wright, G.L.J., 2002. Normal, benign, preneoplastic, and malignant prostate cells have distinct protein expression profiles resolved by Surface Enhanced Laser Desorption/Ionization mass spectrometry.Clin Cancer Res,8(8): 2541–2552.
4. DeAngelis, L.M., 2001. Brain tumors.New England J Medicine,344(2):114–123. DOI: 10.1056/NEJM200101113440207
5. Jemal, A., Murray, T., Samuels, A., Chafoor, A., Ward, E., Thun, M.J., 2003. Cancer statistics, 2003. CA Cancer JCLIN,53(l):5–26. DOI: 10.3322/canjclin.53.1.5
6. Li, J., Zhang, Z., Rosenzweig, J., Wang, Y.Y., Chan, D.W., 2002. Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer.Clin Chem,48(8):1296–1304. DOI: 10.1093/clinchem/48.8.1296
7. Mannes, A.J., Martin, B.M., Yang, H.Y., Keller, J.M., Lewin, S., Gaiser, R.R., Iadarola, M.J., 2003. Cystatin C as a cerebrospinal fluid biomarker for pain in humans.Pain,102(3):251–256. DOI: 10.1016/S0304-3959(02)00403-7
8. Merchant, M., Weinberger, S.R., 2000. Recent advancements in surface-enhanced laser desorption/ionization-time of flight-mass spectrometry.Electrophoresis,21:1164–1177. DOI: 10.1002/(SICI)1522-2683(20000401)21:6<1164::AID-ELPS1164>3.0.CO;2-0
9. Petricoin, E.F., Liotta, L.A., 2004. SELDI-TOF-based serum proteomic pattern diagnostics for early detection of cancer.Curr Opin Biotechnol,15(l):24–30. DOI: 10.1016/j.copbio.2004.01.005
10. Samoylova, T.I., Morrison, N.E., Cox, N.R., 2003. Molecular markers of glial tumors: current targeting strategies.Curr Med Chem,10(10):831–843. DOI: 10.2174/0929867033457737
11. Srinivas, P.R., Verma, M., Zhao, Y., Srivastava, S., Clark, R.A., Tockman, M.S., 2002. Proteomics for cancer biomarker discovery.Clin Chem,48(8): 1160–1169.
12. Wiesner, A., 2004. Detection of tumor markers with proteinchip technology.Curr Pharm Biotechnol,5(l):45–67. DOI: 10.2174/1389201043489675
13. Zhukov, T.A., Johanson, R.A., Cantor, A.B., Clark, R.A., Tockman, M.S., 2003. Discovery of distinct protein profiles specific for lung tumors and pre-malignant lung lesions by SELDI mass spectrometry.Lung Cancer,40(3):267–279. DOI: 10.1016/S0169-5002(03)00082-5