Single-step recovery of ephedrine hydrochloride from raw materials using expanded bed adsorption

Biotechnology Letters

Volumn 26, Issue 15, 2004, Pages 1233-1236

  Chen, Wei Dong ^a   Wang, Yan Dong ^a   Zha, Li Hang ^a   Ma, Guang Hui ^a   Su, Zhi Guo ^a  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

Author keywords

Cation resin; Chromatography; Ephedrine hydrochloride; Expanded bed adsorption

Indexed keywords

ADSORPTION; BENZENE; DISPERSIONS; POSITIVE IONS; PURIFICATION; RAW MATERIALS; RESINS;

BED ADSORPTION; CATION RESINS; HERBS;

EXTRACTION;

CATION EXCHANGE RESIN; EPHEDRINE; HERBACEOUS AGENT;

ARTICLE; CHROMATOGRAPHY; EPHEDRA; EVALUATION; FRACTIONATION; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; ULTRAFILTRATION;

CATION EXCHANGE RESINS; CHEMICAL FRACTIONATION; CHROMATOGRAPHY; DRUGS, CHINESE HERBAL; EPHEDRA; EPHEDRINE; ULTRAFILTRATION;

EID: 16644366465     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:BILE.0000036603.35042.70     Document Type: Article

References (15)

1. Chase HA, Draeger NM (1992) Expanded-bed adsorption of proteins using ion-exchangers. Sep. Sci. Technol. 27: 2021-2039.
2. Chen W-D, Dong X-Y, Sun Y (2003a) Modeling of the whole expanded-bed protein adsorption process with yeast cell suspensions as feedstock. J. Chromatogr. A 1012: 1-10.
3. Chen W-D, Tong X-D, Dong X-Y, Sun Y (2003b) Expanded bed adsorption of protein with DEAE Spherodex M. Biotechnol. Prog. 19: 880-886.
4. Córdoba PR, Ragout AL, Sineriz F, Perotti NI (1996) Lactate from cultures of Lactobacillus casei recovered in a fluidized bed column using ion exchange resin. Biotechnol. Tech. 10: 629-634.
5. Herráez-Hernández R, Campíns-Falcó P (2001) Chiral separation of ephedrines by liquid chromatography using β-cyclodextrins. Anal. Chim. Acta 434: 315-324.
6. Mandwal AK, Tripathi CKM, Trivedi PD, Joshi AK, Agarwal SC, Bihari V (2004) Production of 1-phenylacetyl carbinol by immobilized cells of Saccharomyces cerevisiae. Biotechnol. Lett. 26: 217-221.
7. Lang Q, Wai CM (2001) Supercritical fluid extraction in herbal and natural product studies - a practical review. Talanta 53: 771-782.
8. Pålsson E, Nandakumar MP, Mattiasson B, Larsson PO (2000) Miniaturised expanded-bed column with low dispersion suitable for fast flow-ELISA analyses. Biotechnol. Lett. 22: 245-250.
9. Ren HY (2002) Adsorption chromatography of alkaloids from Ephedra extract. M.Sc. Thesis, Beijing, P.R. China: Chinese Academy of Sciences.
10. Shin HS, Rogers PL (1996) Production of L-Phenylacetylcarbinol (L-PAC) from benzaldehyde using partially purified pyruvate decarboxylase (PDC). Biotechnol. Bioeng. 49: 52-62.
11. Thömmes J, Bader A, Halfar M, Karau A, Kula MR (1996) Isolation of monoclonal antibodies from cell containing hybridoma broth using a protein coated adsorbent in expanded bed. J. Chromatogr. A 752: 111-122.
12. Tripathi CM, Agarwal SC, Basu SK (1997) Production of L-Phenylacetylcarbinol by fermentation. J. Ferment. Bioeng. 84: 487-492.
13. Tsai T-H (2001) Analytical approaches for traditional Chinese medicines exhibiting antineoplastic activity. J. Chromatogr. B 764: 27-48.
14. Wang Y-D, Yuan Y-J, Lu M, Wu J-C, Jiang J-L (2003) Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei. Biotechnol. Appl. Biochem. 37: 39-43.
15. 1 unit in the biosynthesis of ephedrine in Ephedra. Phytochemistry 12: 2877-2882.