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Volumn 11, Issue 2, 2004, Pages 160-168

Prognostic implication of p53 protein expression in relation to nuclear pleomorphism and the MIB-1 counts in breast cancer

Author keywords

Breast cancer; MIB 1; Nuclear pleomorphism; P53

Indexed keywords

KI 67 ANTIGEN; PROTEIN P53; TUMOR MARKER;

EID: 16544395904     PISSN: 13406868     EISSN: 18804233     Source Type: Journal    
DOI: 10.1007/BF02968296     Document Type: Article
Times cited : (9)

References (51)
  • 1
    • 0025876591 scopus 로고
    • The p53 tumour suppressor gene
    • Levine AJ, Momand J, Finlay CA: The p53 tumour suppressor gene. Nature 351:453-456, 1991. (Pubitemid 21896613)
    • (1991) Nature , vol.351 , Issue.6326 , pp. 453-456
    • Levine, A.J.1    Momand, J.2    Finlay, C.A.3
  • 2
    • 0027109075 scopus 로고
    • P53, guardian of the genome
    • Lane DP: P53, guardian of the genome. Nature 358:15-16, 1992.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 3
    • 0027992938 scopus 로고
    • The p53 tumor suppressor gene in breast cancer
    • DOI 10.1007/BF00666204
    • Elledge RM, Allred DC: The p53 tumor suppressor gene in breast cancer. Breast Cancer Res Treat 32:39-47, 1994. (Pubitemid 24322246)
    • (1994) Breast Cancer Research and Treatment , vol.32 , Issue.1 , pp. 39-47
    • Elledge, R.M.1    Allred, D.C.2
  • 4
    • 0023959795 scopus 로고
    • Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
    • Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine A J: Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 8:531-539, 1988.
    • (1988) Mol Cell Biol , vol.8 , pp. 531-539
    • Finlay, C.A.1    Hinds, P.W.2    Tan, T.H.3    Eliyahu, D.4    Oren, M.5    Levine A, J.6
  • 5
    • 0035225608 scopus 로고    scopus 로고
    • Prognostic value of p53 protein expression in breast cancer; An immunohistochemical analysis of frozen sections in 514 Japanese women
    • Tsutsui S, Ohno S, Murakami S, Hachitanda Y, Oda S: Prognostic value of p53 protein expression in breast cancer; An immunohistochemical analysis of frozen sections in 514 Japanese women. Breast Cancer 8:194-201, 2001.
    • (2001) Breast Cancer , vol.8 , pp. 194-201
    • Tsutsui, S.1    Ohno, S.2    Murakami, S.3    Hachitanda, Y.4    Oda, S.5
  • 6
    • 0026659891 scopus 로고
    • Association of overexpression of tumor suppressor protein p53 with rapid cell proliferation and poor prognosis in node-negative breast cancer patients
    • Isola J, Visakorpi T, Holli K, Kallioniemi O: Association of overexpression of tumor suppressor protein p53 with rapid cell proliferation and poor prognosis in node-negative breast cancer patients. J Natl Cancer Inst 84:1109-1114, 1992.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1109-1114
    • Isola, J.1    Visakorpi, T.2    Holli, K.3    Kallioniemi, O.4
  • 8
    • 0027324298 scopus 로고
    • P53 protein expression in breast cancer as related to histopathological characteristics and prognosis
    • Lipponen P, Ji H, Aaltomaa S, Syrjanen S, Syrjanen K: P53 protein expression in breast cancer as related to histopathological characteristics and prognosis. Int J Cancer 55:51-56, 1993. (Pubitemid 23261705)
    • (1993) International Journal of Cancer , vol.55 , Issue.1 , pp. 51-56
    • Lipponen, P.1    Ji, H.2    Aaltomaa, S.3    Syrjanen, S.4    Syrjanen, K.5
  • 9
    • 0027143621 scopus 로고
    • Overexpression of p53 and prognosis in breast cancer
    • DOI 10.1002/1097-0142(19931215)72:12<3641::AID-CNCR2820721215>3.0. CO;2-8
    • Ffiedrichs K, Gluba S, Eidtmann H, Jonat W: Overexpression of p53 and prognosis in breast cancer. Cancer 72:3641-3647, 1993. (Pubitemid 24000599)
    • (1993) Cancer , vol.72 , Issue.12 , pp. 3641-3647
    • Friedrichs, K.1    Gluba, S.2    Eidtmann, H.3    Jonat, W.4
  • 12
    • 0030002609 scopus 로고    scopus 로고
    • Relationship between p53 gene abnormalities and other tumour characteristics in breast-cancer prognosis
    • DOI 10.1002/(SICI)1097-0215(19960422)69:2<135::AID-IJC12>3.0.CO;2-8
    • Seshadri R, Leong AS, McCaul K, Firgaira FA, Setlur V, Horsfall D J: Relationship between p53 gene abnormalities and other tumor characteristics in breast-cancer prognosis. IntJ Cancer 69:135-141, 1996. (Pubitemid 26164863)
    • (1996) International Journal of Cancer , vol.69 , Issue.2 , pp. 135-141
    • Seshadri, R.1    Leong, A.S.-Y.2    Mccaul, K.3    Firgaira, F.A.4    Setlur, V.5    Horsfall, D.J.6
  • 17
    • 0027278584 scopus 로고
    • Immunohistochemical detection of p53 protein in mammary carcinoma: An important new independent indicator of prognosis?
    • DOI 10.1016/0046-8177(93)90158-D
    • Barnes DM, Dublin EA, Fisher CJ, Levison DA, Millis RR: Immunohistochemical detection of p53 protein in mammary carcinoma: An important new independent indicator of prognosis? Hum Patho124:469-476, 1993. (Pubitemid 23145798)
    • (1993) Human Pathology , vol.24 , Issue.5 , pp. 469-476
    • Barnes, D.M.1    Dublin, E.A.2    Fisher, C.J.3    Levison, D.A.4    Millis, R.R.5
  • 20
    • 0026471731 scopus 로고
    • Abnormal p53 immunoreactivity and prognosis in nodenegative breast carcinomas with long-term follow-up
    • Bosari S, Lee AKC, Viale G, Heatley GJ, Coggi G: Abnormal p53 immunoreactivity and prognosis in nodenegative breast carcinomas with long-term follow-up. Virchows Archiv A Pathol Anat 421:291-295, 1992.
    • (1992) Virchows Archiv A Pathol Anat , vol.421 , pp. 291-295
    • Bosari, S.1    Lee, A.K.C.2    Viale, G.3    Heatley, G.J.4    Coggi, G.5
  • 21
    • 0026795005 scopus 로고
    • P53 expression in human breast carcinoma: Relationship to expression of epidermal growth factor receptor, cerbB-2 protein overexpression, and oestrogen receptor
    • Poller DN, Hutchings CE, Galea M, Bell JA, Nicholson RA, Elston CW, Blarney RW, Ellis IO: P53 expression in human breast carcinoma: Relationship to expression of epidermal growth factor receptor, cerbB-2 protein overexpression, and oestrogen receptor. Br J Cancer 66:583-588, 1992.
    • (1992) Br J Cancer , vol.66 , pp. 583-588
    • Poller, D.N.1    Hutchings, C.E.2    Galea, M.3    Bell, J.A.4    Nicholson, R.A.5    Elston, C.W.6    Blarney, R.W.7    Ellis, I.O.8
  • 25
    • 0028986873 scopus 로고
    • P53 in node-negative breast carcinoma: An immunohistochemical study of epidemiologic risk factors, histologic features, and prognosis
    • Rosen PP, Lesser ML, Arroy CD, Cranor M, Borgen P, Norton L: P53 in node-negative breast carcinoma: An immunohistochemical study of epidemiologic risk factors, histologic features, and prognosis. J Clin Onco113:821-830, 1995.
    • (1995) J Clin Oncol , vol.13 , pp. 821-830
    • Rosen, P.P.1    Lesser, M.L.2    Arroy, C.D.3    Cranor, M.4    Borgen, P.5    Norton, L.6
  • 26
    • 0028948129 scopus 로고
    • An immunohistochemical study of p53 with correlations to histopathological parameters, c-erbB-2, proliferating cell nuclear antigen, and prognosis
    • Haerslev T, Jacobsen GK: An immunohistochemical study of p53 with correlations to histopathological parameters, c-erbB-2, proliferating cell nuclear antigen, and prognosis. Hum Patho126:295-301, 1995.
    • (1995) Hum Pathol , vol.26 , pp. 295-301
    • Haerslev, T.1    Jacobsen, G.K.2
  • 28
    • 70449185514 scopus 로고
    • Histological grading and prognosis in breast cancer
    • Bloom HJG, Richardson WW: Histological grading and prognosis in breast cancer. Br J Cancer 11:359-377, 1957.
    • (1957) Br J Cancer , vol.11 , pp. 359-377
    • Bloom, H.J.G.1    Richardson, W.W.2
  • 29
    • 0023620135 scopus 로고
    • Histologic malignancy grading of invasive ductal breast carcinoma. A regression analysis of prognostic factors in low-risk carcinomas from a multicenter trial
    • Rank F, Dombernowsky P, Jespersen NCB, Pedersen BV, Keiding N: Histologic malignancy grading of invasive ductal breast carcinoma. A regression analysis of prognostic factors in low-risk carcinomas from a multicenter trial. Cancer 60:1599-1305, 1987.
    • (1987) Cancer , vol.60 , pp. 1599-1305
    • Rank, F.1    Dombernowsky, P.2    Jespersen, N.C.B.3    Pedersen, B.V.4    Keiding, N.5
  • 30
    • 0033015048 scopus 로고    scopus 로고
    • Comparison of mitotic index, in vitro bromodeoxyuridine labeling, and mib-1 assays to quantitate proliferation in breast cancer
    • Thor AD, Liu S, Moore II DH, Edgerton SM: Comparison of mitotic index, in vitro bromodeoxyuridine labeling, and MIB-1 assays to quantitate proliferation in breast cancer. J Clin Oncol 17:470-477, 1999. (Pubitemid 29075230)
    • (1999) Journal of Clinical Oncology , vol.17 , Issue.2 , pp. 470-477
    • Thor, A.D.1    Liu, S.2    Moore II, D.H.3    Edgerton, S.M.4
  • 32
    • 0027494994 scopus 로고
    • Prognostic value of p53 protein expression in breast carcinomas
    • Hurlimann J: Prognostic value of p53 protein expression in breast carcinomas. Path Res Pract 189:996-1003, 1993. (Pubitemid 23363272)
    • (1993) Pathology Research and Practice , vol.189 , Issue.9 , pp. 996-1003
    • Hurlimann, J.1
  • 34
    • 0029079713 scopus 로고
    • P53 in breast cancer. Its relation to histological grade, lymph-node status, hormone receptors, cell-proliferation faraction (ki-67) and c-erbB-2. Immunohistochemical study of 153 cases
    • Sirvent JJ, Salvado MT, Santafe M, Martinez S, Brunet J, Alvaro T, Palacios J: P53 in breast cancer. Its relation to histological grade, lymph-node status, hormone receptors, cell-proliferation faraction (ki-67) and c-erbB-2. Immunohistochemical study of 153 cases. Histol Histopathol 10:531-539, 1995.
    • (1995) Histol Histopathol , vol.10 , pp. 531-539
    • Sirvent, J.J.1    Salvado, M.T.2    Santafe, M.3    Martinez, S.4    Brunet, J.5    Alvaro, T.6    Palacios, J.7
  • 36
    • 0030819466 scopus 로고    scopus 로고
    • Cytometric DNA analysis and prognostic biomarkers in breast carcinoma. Expression of P53 product in the different ploidy classes
    • Leonardi E,Cristofori A, Caffo O, Palma PD: Cytometric DNA analysis and prognostic biomarkers in breast carcinoma. Expression of P53 product in the different ploidy classes. Anal Cell Pathol 15:31-45, 1997. (Pubitemid 27448891)
    • (1997) Analytical Cellular Pathology , vol.15 , Issue.1 , pp. 31-45
    • Leonardi, E.1    Cristofori, A.2    Caffo, O.3    Dalla Palma, P.4
  • 37
    • 0032450927 scopus 로고    scopus 로고
    • Relationship between AgNOR proteins, Ki-67 antigen, p53 immunophenotype and differentiation markers in archival breast carcinomas
    • Bankfalvi A, Schmitz K, Mock T, Kemper M, Cubick C, Bocker W: Relationship between AgNOR proteins, Ki-67 antigen, p53 immunophenotype and differentiation markers in archival breast carcinomas. Anal Cell Pathol 17:231-242, 1998. (Pubitemid 29243076)
    • (1998) Analytical Cellular Pathology , vol.17 , Issue.4 , pp. 231-242
    • Bankfalvi, A.1    Schmitz, K.2    Mock, T.3    Kemper, M.4    Cubick, C.5    Bocker, W.6
  • 38
    • 0029009756 scopus 로고
    • P53 antigen loss in stored paraffin slides
    • Prioleau J, Schnitt SJ: P53 antigen loss in stored paraffin slides. New EnglJMed 332:1521-1522, 1995.
    • (1995) New EnglJMed , vol.332 , pp. 1521-1522
    • Prioleau, J.1    Schnitt, S.J.2
  • 39
    • 0027564043 scopus 로고
    • P53 protein immunostaining in routinely processed paraffin-embedded sections
    • Bruner JM, Connelly JH, Saya H: P53 protein immunostaining in routinely processed paraffin-embedded sections. Mod Pathol 6:189-194, 1993.
    • (1993) Mod Pathol , vol.6 , pp. 189-194
    • Bruner, J.M.1    Connelly, J.H.2    Saya, H.3
  • 40
    • 0030869514 scopus 로고    scopus 로고
    • Comparison of quantitative and semiquantitative methods of assessing MIB-1 with the S-phase fraction in breast carcinoma
    • MacGrogan G, Jollet I, Huet S, Sierankowski G, Picot V, Bonichon F, Coindre JM: Comparison of quantitative and semiquanfitative methods of assessing MIB-1 with the S-phase fraction in breast carcinoma. Mod Pathol 10:769-776, 1997. (Pubitemid 27374846)
    • (1997) Modern Pathology , vol.10 , Issue.8 , pp. 769-776
    • MacGrogan, G.1    Jollet, I.2    Huet, S.3    Sierankowski, G.4    Picot, V.5    Bonichon, F.6    Coindre, J.M.7
  • 42
    • 0028277851 scopus 로고
    • Cell kinetics in human breast cancer: Comparison between the prognostic value of the cytofluorimetric S-phase fraction and that of the antibodies to Ki-67 and PCNA antigens detected by immunocytochemistry
    • DOI 10.1002/ijc.2910570610
    • Gasparini G, Boracchi P, Verderio P, Bevilacqua P: Cell kinetics in human breast cancer: Comparison between the prognostic value of the cytofluorimetric s-phase fraction and that of the antibodies to Ki-67 and PCNA antigens detected by immunocytochemistry. IntJ Cancer 57:822-829, 1994. (Pubitemid 24216818)
    • (1994) International Journal of Cancer , vol.57 , Issue.6 , pp. 822-829
    • Gasparini, G.1    Boracchi, P.2    Verderio, P.3    Bevilacqua, P.4
  • 43
    • 0029039796 scopus 로고
    • Proliferation markers in breast carcinoma. Mitotic figure count, S-phase fraction, proliferating cell nuclear antigen, Ki-67 and MIB-1 counts
    • Kesgegian AA, Cnaan A: Proliferation markers in breast carcinoma. Mitotic figure count, S-phase fraction, proliferating cell nuclear antigen, Ki-67 and MIB-1 counts. AmJ Clin Pathol 104:42-49, 1995.
    • (1995) AmJ Clin Pathol , vol.104 , pp. 42-49
    • Kesgegian, A.A.1    Cnaan, A.2
  • 45
    • 0030069047 scopus 로고    scopus 로고
    • Long term prognostic value of growth fraction determination by Ki-67 immunostaining in primary operable breast cancer
    • DOI 10.1007/BF01806632
    • Pierga JY, Leroyer Aa, Viehl P, Mosseri V, Chevillard S, Magdelenat H: Long term prognostic value of growth fraction determination by Ki-67 immunostaining in primary operable breast cancer. Breast Cancer Res Treat 37:57-64, 1996. (Pubitemid 26028246)
    • (1996) Breast Cancer Research and Treatment , vol.37 , Issue.1 , pp. 57-64
    • Pierga, J.-Y.1    Leroyer, A.2    Viehl, P.3    Mosseri, V.4    Chevillard, S.5    Magdelenat, H.6
  • 46
  • 47
    • 0030010161 scopus 로고    scopus 로고
    • Prognostic value of Ki-67 compared to S-Phase fraction in axillary node-negative breast cancer
    • Brown RW, Allred DC, Clark GM, Osborne CK, Hilsenbeck SG: Prognostic value of Ki-67 compared to S-phase fraction in axillary node-negative breast cancer. Clin Cancer Res 2:585-592, 1996. (Pubitemid 26099178)
    • (1996) Clinical Cancer Research , vol.2 , Issue.3 , pp. 585-592
    • Brown, R.W.1    Allred, D.C.2    Clark, G.M.3    Osborne, C.K.4    Hilsenbeck, S.G.5
  • 49
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes J, Lemke H, Baisch H, Wacker H, Schwab U, Stein H: Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immuno1133:1710-1715, 1984. (Pubitemid 14035254)
    • (1984) Journal of Immunology , vol.133 , Issue.4 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3
  • 50
    • 0027057589 scopus 로고
    • Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections
    • DOI 10.1002/path.1711680404
    • Cattoretti G, Becker MHG, Key G, Duchrow M, Schluter C, Galle J, Gerdes J: Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwaveprocessed formalin-fixed paraffin sections. J Pathol 168:357-363, 1992. (Pubitemid 23013251)
    • (1992) Journal of Pathology , vol.168 , Issue.4 , pp. 357-363
    • Cattoretti, G.1    Becker, M.H.G.2    Key, G.3    Duchrow, M.4    Schluter, C.5    Galle, J.6    Gerdes, J.7
  • 51
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
    • Michalovitz D, Halevy O, Oren M: Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62:671-680, 1990.
    • (1990) Cell , vol.62 , pp. 671-680
    • Michalovitz, D.1    Halevy, O.2    Oren, M.3


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