Assessment of Phospholipid Malabsorption by Quantification of Fecal Phospholipid

Journal of Pediatric Gastroenterology and Nutrition

Volumn 39, Issue 1, 2004, Pages 85-91

  Chen, Alice ^a   Innis, Sheila ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cystic fibrosis; Fecal lipid extraction; Fecal phospholipids; Malabsorption; Pancreatic insufficiency; Steatorrhea

Indexed keywords

PHOSPHOLIPID;

ARTICLE; CASE CONTROL STUDY; CHEMISTRY; CHILD; COLORIMETRY; CYSTIC FIBROSIS; FECES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALABSORPTION; METABOLISM; METHODOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

CASE-CONTROL STUDIES; CHILD; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLORIMETRY; CYSTIC FIBROSIS; FECES; HUMANS; MALABSORPTION SYNDROMES; PHOSPHOLIPIDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 16544392953     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/00005176-200407000-00017     Document Type: Article

References (23)

1. Zeisel SH, Growdon JH, Wurtman RJ, et al. Normal plasma choline responses to ingested lecithin. Neurology 1980;30:1226-9.
2. Carey MC, Hernell O. Digestion and absorption of fat. Semin Gastrointest Dis 1992;3:189-208.
3. Zeisel SH, Da Costa K, Franklin PD, et al. Choline, an essential nutrient for humans. FASEB J 1991;5:2093-8.
4. Canty DJ, Zeisel SH. Lecithin and choline in human health and disease. Nutr Rev 1994;52:327-39.
5. Brouwers JFHM, Gadella BM, van Golde LMG, et al. Quantitative analysis of phosphatidylcholine molecular species using HPLC and light scattering detection. J Lip Res 1998;39:344-53.
6. Institute of Medicine. Choline. In:Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: National Academy Press; 2000:390-422.
7. Greenberger NJ, Isselbacher KJ. Diseases of the gallbladder and bile ducts. In: Fauci A, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, eds. Harrison's Principles of Internal Medicine. New York: McGraw-Hill; 1998:1725-6.
8. Waters DL, Dorney SF, Gaskin KJ, et al. Pancreatic function in infants identified as having cystic fibrosis in a neonatal screening program. N Engl J Med 1990;322:303-8.
9. Couper RT, Corey M, Moore DJ, et al. Decline of exocrine pancreatic function in cystic fibrosis patients with pancreatic sufficiency. Pediatr Res 1992;32:179-82.
10. Borowitz D, Baker RD, Stallings V. Consensus report on nutrition for pediatric patients with cystic fibrosis. J Pediatr Gastroenterol Nutr 2002;35:246-59.
11. Innis SM, Davidson AGF, Chen A, et al. Increased plasma homocysteine and s-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis. J Pediatr 2003;143:351-6.
12. Colombo C, Apostolo MG, Ferrari M, et al. Analysis of risk factors for the development of liver disease associated with cystic fibrosis. J Pediatr 1994;124:393-9.
13. Yao Z, Vance DE. Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes. J Biol Chem 1989;264:11373-80.
14. Van de Kamer JH, Ten Bokkel Huinink H, Weyers HA. Rapid method for the determination of fat in feces. J Biol Chem 1949;177:347-55.
15. Jeejeebhoy HN, Ahmad S, Kozak G. Determination of fecal fats containing both medium and long chain triglycerides and fatty acids. Clin Biochem 1970;3:157-63.
16. Folch J, Lees M, Sloane-Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957;226:497-509.
17. Chen PS, Toribara TY, Warner H. Microdetermination of phosphorus. Anal Chem 1956;28:1756-8.
18. Innis SM, Dyer RA. Brain astrocyte synthesis of docosahexaenoic acid from n-3 fatty acids is limited at the elongation of docosapentaenoic acid. J Lipid Res 2002;43:1529-36.
19. Rouser G, Siakotos AN, Fleischer S. Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots. Lipids 1965;1:85-6.
20. Nouri-Sorkhabi MH, Chapman BE, Kuchel PW, et al. Parallel secretion of pancreatic phospholipase A2, phospholipase A1, lipase, and colipase in children with exocrine pancreatic dysfunction. Pediatr Res 2000;48:735-40.
21. Dressman JB, Shtohryn LV, Diokno D. Effects of product formulation on in vitro activity of pancreatic enzymes. Am J Hosp Pharm 1985;42:2502-6.
22. Barraclough M, Taylor CJ. Twenty-four hour ambulatory gastric and duodenal pH profiles in cystic fibrosis: effect of duodenal hyperacidity on pancreatic enzyme function and fat absorption. J Pediatr Gastroenterol Nutr 1996;23:45-50.
23. Buchman AL, Ament ME, Sohel M, et al. Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: proof of a human choline requirement: a placebo-controlled trial. JPEN J Parenter Enteral Nutr 2001;25:260-8.