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Volumn 11, Issue 5, 2004, Pages 943-950

A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells

Author keywords

Biomodulator; Combinatory treatment; Hepatocellular carcinoma; Retinoids; Tamoxifen; Trichostatin A

Indexed keywords

ANTIESTROGEN; ANTINEOPLASTIC AGENT; BAX PROTEIN, HUMAN; BAX PROTEIN, MOUSE; BAX PROTEIN, RAT; BIOLOGICAL RESPONSE MODIFIER; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, MOUSE; CASP3 PROTEIN, RAT; CASPASE; CASPASE 3; CDKN1A PROTEIN, HUMAN; CDKN1A PROTEIN, MOUSE; CDKN1A PROTEIN, RAT; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; CYCLOHEXANE DERIVATIVE; DNA; ENZYME INHIBITOR; FUMAGILLOL CHLOROACETYLCARBAMATE; HYDROXAMIC ACID; O-(CHLOROACETYLCARBAMOYL)FUMAGILLOL; PROTEIN BAX; PROTEIN BCL 2; RETINOIC ACID; SESQUITERPENE; TAMOXIFEN; TRICHOSTATIN A;

EID: 16544389873     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.11.5.943     Document Type: Article
Times cited : (10)

References (31)
  • 3
    • 0035729049 scopus 로고    scopus 로고
    • Systemic treatment of hepatocellular carcinoma
    • Treiber G: Systemic treatment of hepatocellular carcinoma. Dig Dis 19: 311-323, 2001.
    • (2001) Dig Dis , vol.19 , pp. 311-323
    • Treiber, G.1
  • 4
    • 0036133843 scopus 로고    scopus 로고
    • Combined in vitro anti-tumoral action of Tamoxifen and retinoic acid derivatives in hepatoma cells
    • Herold C, Ganslmayer M, Ocker M, et al: Combined in vitro anti-tumoral action of Tamoxifen and retinoic acid derivatives in hepatoma cells. Int J Oncol 20: 89-96, 2002.
    • (2002) Int J Oncol , vol.20 , pp. 89-96
    • Herold, C.1    Ganslmayer, M.2    Ocker, M.3
  • 5
    • 0034030096 scopus 로고    scopus 로고
    • Induction of apoptosis by mifepristone and tamoxifen in human LNCaP prostate cancer cells in culture
    • DOI 10.1002/(SICI)1097-0045(20000401)43:1<31::AID-
    • El Etreby MF, Ling and Lewis RW: Induction of apoptosis by mifepristone and tamoxifen in human LNCaP prostate cancer cells in culture. Prostate 43: 31-42, 2000. (Pubitemid 30164241)
    • (2000) Prostate , vol.43 , Issue.1 , pp. 31-42
    • El, E.M.F.1    Liang, Y.2    Lewis, R.W.3
  • 6
    • 0032482661 scopus 로고    scopus 로고
    • Tamoxifen in treatment of hepatocellular carcinoma: A randomised controlled trial
    • CLIP Group
    • CLIP Group: Tamoxifen in treatment of hepatocellular carcinoma: a randomised controlled trial. Lancet 352: 17-20, 1998.
    • (1998) Lancet , vol.352 , pp. 17-20
  • 7
    • 0033118925 scopus 로고    scopus 로고
    • Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma [4]
    • DOI 10.1056/NEJM199904013401315
    • Muto Y, Moriwaki H and Saito A: Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma. N Engl J Med 340: 1046-1047, 1999. (Pubitemid 29157643)
    • (1999) New England Journal of Medicine , vol.340 , Issue.13 , pp. 1046-1047
    • Muto, Y.1    Moriwaki, H.2    Saito, A.3
  • 8
    • 0033109775 scopus 로고    scopus 로고
    • Retinoid receptors in health and disease: Co-regulators and the chromatin connection
    • Minucci S and Pelicci PG: Retinoid receptors in health and disease: co-regulators and the chromatin connection. Semin Cell Dev Biol 10: 215-225, 1999. (Pubitemid 129502413)
    • (1999) Seminars in Cell and Developmental Biology , vol.10 , Issue.2 , pp. 215-225
    • Minucci, S.1    Pelicci, P.G.2
  • 9
    • 0034114690 scopus 로고    scopus 로고
    • Retinoid-dependent growth inhibition, differentiation and apoptosis in acute promyelocytic leukemia cells. Expression and activation of caspases
    • Gianni M, Ponzanelli I, Mologni L, et al: Retinoid-dependent growth inhibition, differentiation and apoptosis in acute promyelocytic leukemia cells. Expression and activation of caspases. Cell Death Differ 7: 447-460, 2000. (Pubitemid 30255713)
    • (2000) Cell Death and Differentiation , vol.7 , Issue.5 , pp. 447-460
    • Gianni, M.1    Ponzanelli, I.2    Mologni, L.3    Reichert, U.4    Rambaldi, A.5    Terao, M.6    Garattini, E.7
  • 10
    • 0034131857 scopus 로고    scopus 로고
    • Angiogenesis inhibitor TNP-470 suppresses the progression of experimentally-induced hepatocellular carcinoma in rats
    • Kin M, Torimura T, Ueno T, et al: Angiogenesis inhibitor TNP-470 suppresses the progression of experimentally-induced hepatocellular carcinoma in rats. Int I Oncol 16: 375-382, 2000.
    • (2000) Int I Oncol , vol.16 , pp. 375-382
    • Kin, M.1    Torimura, T.2    Ueno, T.3
  • 11
    • 0034243139 scopus 로고    scopus 로고
    • Contribution of angiogenesis to the progression of colon cancer: Possible inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and hepatic metastasis
    • Takatsuka S, Yamada N, Sawada T, et al: Contribution of angiogenesis to the progression of colon cancer: possible inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and hepatic metastasis. Int J Oncol 17: 253-258, 2000.
    • (2000) Int J Oncol , vol.17 , pp. 253-258
    • Takatsuka, S.1    Yamada, N.2    Sawada, T.3
  • 12
    • 0033711746 scopus 로고    scopus 로고
    • Characterization of TNP-470-induced modifications to cell functions in HUVEC and cancer cells
    • Farinelle S, Malonne H, Chaboteaux C, et al: Characterization of TNP-470-induced modifications to cell functions in HUVEC and cancer cells. J Pharmacol Toxicol Methods 43: 15-24, 2000.
    • (2000) J Pharmacol Toxicol Methods , vol.43 , pp. 15-24
    • Farinelle, S.1    Malonne, H.2    Chaboteaux, C.3
  • 14
    • 0036171675 scopus 로고    scopus 로고
    • Trichostatin A blocks proliferation and triggers apoptosis in heptoma cells
    • Herold C, Ganslmayer M, Ocker M, et al: Trichostatin A blocks proliferation and triggers apoptosis in heptoma cells. J Hepatol 36: 233-240, 2002.
    • (2002) J Hepatol , vol.36 , pp. 233-240
    • Herold, C.1    Ganslmayer, M.2    Ocker, M.3
  • 15
    • 0030796349 scopus 로고    scopus 로고
    • Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin a (Inhibitors of histone deacetylase): Dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway
    • Medina V, Edmonds B, Young GP, et al: Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. Cancer Res 57: 3697-3707, 1997. (Pubitemid 27381212)
    • (1997) Cancer Research , vol.57 , Issue.17 , pp. 3697-3707
    • Medina, V.1    Edmonds, B.2    Young, G.P.3    James, R.4    Appleton, S.5    Zalewski, P.D.6
  • 16
    • 0036176617 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer treatment
    • DOI 10.1097/00001813-200201000-00001
    • Vigushin DM and Coombes RC: Histone deacetylase inhibitors in cancer treatment. Anticancer Drugs 3: 1-13, 2002. (Pubitemid 34169522)
    • (2002) Anti-Cancer Drugs , vol.13 , Issue.1 , pp. 1-13
    • Vigushin, D.M.1    Coombes, R.C.2
  • 17
    • 0034837064 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylase as new anticancer agent
    • Jung M: Inhibitors of histone deacetylase as new anticancer agent. Curr Med Chem 8: 1505-1511, 2001.
    • (2001) Curr Med Chem , vol.8 , pp. 1505-1511
    • Jung, M.1
  • 18
    • 0034544533 scopus 로고    scopus 로고
    • Pharmacodynamics of tamoxifen and its 4-hydroxy and N-desmethyl metabolites: Activation of caspases and induction of apoptosis in rat mammary tumors and in human breast cancer cell lines
    • Mandlekar S, Hebbar V, Christov K and Kong AN: Pharmacodynamics of tamoxifen and its 4-hydroxy and N-desmethyl metabolites: activation of caspases and induction of apoptosis in rat mammary tumors and in human breast cancer cell lines. Cancer Res 60: 6601-6606, 2000.
    • (2000) Cancer Res , vol.60 , pp. 6601-6606
    • Mandlekar, S.1    Hebbar, V.2    Christov, K.3    Kong, A.N.4
  • 19
    • 0035181465 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen-induced apoptosis
    • DOI 10.1023/A:1012437607881
    • Mandlekar S and Kong AN: Mechanisms of tamoxifen-induced apoptosis. Apoptosis 6: 469-477, 2001. (Pubitemid 33078758)
    • (2001) Apoptosis , vol.6 , Issue.6 , pp. 469-477
    • Mandlekar, S.1    Kong, A.-N.T.2
  • 21
    • 0023573087 scopus 로고
    • Interaction of retinoids and tamoxifen on the inhibition of human mammaty cell proliferation
    • Fontana JA: Interaction of retinoids and tamoxifen on the inhibition of human mammaty cell proliferation. Exp Cell Biol 55: 136-144, 1986.
    • (1986) Exp Cell Biol , vol.55 , pp. 136-144
    • Fontana, J.A.1
  • 22
    • 0034183319 scopus 로고    scopus 로고
    • Combined treatment with TNP-470 and 5-fluorouracil effectively inhibits growth of murine colon cancer cells in vitro and liver metastasis in vivo
    • Ogawa H, Sato Y, Kondo M, et al: Combined treatment with TNP-470 and 5-fluorouracil effectively inhibits growth of murine colon cancer cells in vitro and liver metastasis in vivo. Oncol Rep 7: 467-72, 2000.
    • (2000) Oncol Rep , vol.7 , pp. 467-472
    • Ogawa, H.1    Sato, Y.2    Kondo, M.3
  • 24
  • 25
    • 0036045455 scopus 로고    scopus 로고
    • p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells
    • Martinez LA, Yang J, Vazquez ES, et al: p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells. Carcinogenesis 23: 1289-1296, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 1289-1296
    • Martinez, L.A.1    Yang, J.2    Vazquez, E.S.3
  • 26
    • 0037183697 scopus 로고    scopus 로고
    • Transcriptional regulation during p21/WAF1/Cip1-induced apoptosis in human ovarian cancer cells
    • Wu Q, Kirschmeier P, Hockenberry T, et al: Transcriptional regulation during p21/WAF1/Cip1-induced apoptosis in human ovarian cancer cells. J Biol Chem 277: 36329-36337, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 36329-36337
    • Wu, Q.1    Kirschmeier, P.2    Hockenberry, T.3
  • 27
    • 0035283079 scopus 로고    scopus 로고
    • Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3
    • DOI 10.1182/blood.V97.5.1378
    • Wieder T, Essmann F, Prokop A, et al: Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3. Blood 97: 1378-1387, 2001. (Pubitemid 32183762)
    • (2001) Blood , vol.97 , Issue.5 , pp. 1378-1387
    • Wieder, T.1    Essmann, F.2    Prokop, A.3    Schmelz, K.4    Schulze-Osthoff, K.5    Beyaert, R.6    Dorken, B.7    Daniel, P.T.8
  • 28
    • 0033403558 scopus 로고    scopus 로고
    • Involvement of nuclear steroid/thyroid/retinoid receptors and of protein kinases in the regulation of growth and of c-erbB and retinoic acid receptor expression in MCF-7 breast cancer cells
    • DOI 10.1023/A:1006377006816
    • Schneider SM, Offterdinger M, Huber H and Grunt TW: Involvement of nuclear steroid/thyroid/retinoid receptors and of protein kinases in the regulation of growth and ofc-erbB and retinoic acid receptor expression in MCF-7 breast cancer cells. Breast Cancer Res Treat 58: 171-181, 1999. (Pubitemid 30032490)
    • (1999) Breast Cancer Research and Treatment , vol.58 , Issue.2 , pp. 171-181
    • Schneider, S.M.1    Offterdinger, M.2    Huber, H.3    Grunt, T.W.4
  • 29
    • 0035683554 scopus 로고    scopus 로고
    • Nuclear receptors, coregulators, ligands, and selective receptor modulators: Making sense of the patchwork quilt
    • McKenna NJ and O'Malley BW: Nuclear receptors, coregulators, ligands, and selective receptor modulators: making sense of the patchwork quilt. Ann NY Acad Sci 949: 3-5, 2001.
    • (2001) Ann NY Acad Sci , vol.949 , pp. 3-5
    • McKenna, N.J.1    O'Malley, B.W.2
  • 31
    • 0030953186 scopus 로고    scopus 로고
    • Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
    • DOI 10.1016/S0092-8674(00)80218-4
    • Nagy L, Kao HY, Chakravarti D, et al: Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell-89: 373-380, 1997. (Pubitemid 27220882)
    • (1997) Cell , vol.89 , Issue.3 , pp. 373-380
    • Nagy, L.1    Kao, H.-Y.2    Chakravarti, D.3    Lin, R.J.4    Hassig, C.A.5    Ayer, D.E.6    Schreiber, S.L.7    Evans, R.M.8


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