Glycerol enhances CDDP-induced growth inhibition of thyroid anaplastic carcinoma tumor carrying mutated p53 gene

Oncology Reports

Volumn 11, Issue 4, 2004, Pages 821-824

  Yuki, Kazue ^a   Takahashi, Akihisa ^a   Ota, Ichiro ^a   Ohnishi, Ken ^a   Yasumoto, Jun Ichi ^a   Kanata, Hirokazu ^a   Yane, Katsunari ^a   Hosoi, Hiroshi ^a   Ohnishi, Takeo ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Anaplastic thyroid carcinoma; Apoptosis; CDDP; Glycerol; p53

Indexed keywords

ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, MOUSE; CASPASE; CASPASE 3; CISPLATIN; GLYCEROL;

ANIMAL; ANIMAL MODEL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; CARCINOMA; CULTURE TECHNIQUE; DRUG EFFECT; DRUG POTENTIATION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MOUSE; PATHOLOGY; POINT MUTATION; THYROID TUMOR; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CARCINOMA; CASPASE 3; CASPASES; CELL CULTURE TECHNIQUES; CISPLATIN; DRUG SYNERGISM; GENES, P53; GLYCEROL; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; NEOPLASM TRANSPLANTATION; POINT MUTATION; THYROID NEOPLASMS;

EID: 16544388628     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Tan RK, Finley RK III, Driscoll D, Bakamjian V, Hicks WL Jr and Shedd DP: Anaplastic carcinoma of the thyroid: a 24-year experience. Head Neck 17: 41-47, 1995.
2. Sweeney PJ, Haraf DJ, Recant W, Kaplan El and Vokes EE: Anaplastic carcinoma of the thyroid. Ann Oncol 7: 739-744, 1996. (Pubitemid 26323548)
3. Venkatesh YS, Ordonez NG, Schultz PN, Hickey RC, Goepfert H and Samaan NA: Anaplastic carcinoma of the thyroid. A clinicopathologic study of 121 cases. Cancer 66: 321-330, 1990. (Pubitemid 20205915)
4. Jereb B, Stjernsward J and Lowhagen T: Anaplastic giant-cell carcinoma of the thyroid. A study of treatment and prognosis. Cancer 35: 1293-1295, 1975.
5. Aldinger KA, Samaan NA and Hill CS Jr: Anaplastic carcinoma of the thyroid: a review of 84 cases of spindle and giant cell carcinoma of the thyroid. Cancer 41: 2267-2275, 1978. (Pubitemid 8370197)
6. Ito T, Seyama T, Mizuno T, Tsuyama N, Hayashi T, Hayashi Y, Dohi K, Nakamura N and Akiyama M: Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland. Cancer Res 52: 1369-1371, 1992.
7. Fagin JA, Matsuo K, Karmakar A, Chen DL, Tang SH and Koeffler HP: High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 91: 179-184, 1993. (Pubitemid 23037270)
8. Caelles C, Helmberg A and Karin M: p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370: 220-223, 1994. (Pubitemid 24236778)
9. Dulic V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ and Reed SI: p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G t arrest. Cell 76: 1013-1023, 1994. (Pubitemid 24106382)
10. 1 arrest and apoptosis. Cancer Res 54: 1169-1174, 1994.
11. Waga S, Hannon GJ, Beach D and Stillman B: The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369: 574-577, 1994.
12. Takahashi A: Pre-irradiation at a low dose-rate blunted p53 response. J Radiat Res 43: 1-9, 2002.
13. Lowe SW: Cancer therapy and p53. Curr Opin Oncol 7: 547-553, 1995.
14. Rhee JG, Kim TH, Levitt SH and Song CW: Changes in acidity of mouse tumor by hyperthermia. Int J Radiat Oncol Biol Phys 10: 393-399, 1984. (Pubitemid 14110175)
15. Bicher HI, Hetzel FW, Sandhu TS, Frinak S, Vaupel P, O'Hara MD and O'Brien T: Effects of hyperthermia on normal and tumor microenvironment. Radiology 137: 523-530, 1980. (Pubitemid 10008932)
16. Ohnishi T, Takahashi A, Yano T, Matsumoto H, Wang X, Ohnishi K, Tamamoto T, Tsuji K, Furusawa Y and Yukawa O: Hyperthermic enhancement of tumour growth inhibition by accelerated carbon-ions in transplantable human esophageal cancer. Int J Hyperthermia 14: 195-202, 1998. (Pubitemid 28177299)
17. Asakawa I, Yoshimura H, Takahashi A, Ohnishi K, Nakagawa H, Ota I, Furusawa Y, Tamamoto T, Ohishi H and Ohnishi T: Radiation-induced growth inhibition in transplanted human tongue carcinomas with different p53 gene status. Anticancer Res 22: 2037-2043, 2002. (Pubitemid 34857020)
18. Yasumoto J, Imai Y, Takahashi A, Ohnishi K, Yuki K, Kirita T and Ohnishi T: Analysis of apoptosis-related gene expression after X-ray irradiation in human tongue squamous cell carcinoma cells harboring wild-type or mutated p53 gene. J Radiat Res 44: 41-45, 2003. (Pubitemid 38738754)
19. Kanata H, Yane K, Ota I, Miyahara H, Matsunaga T, Takahashi A, Ohnishi K, Ohnishi T and Hosoi H: CDDP induces p53-dependent apoptosis in tongue cancer cells. Int J Oncol 17: 513-517, 2000.
20. Ota I, Ohnishi K, Takahashi A, Yane K, Kanata H, Miyahara H, Ohnishi T and Hosoi H: Transfection with mutant p53 gene inhibits heat-induced apoptosis in a head and neck cell line of human squamous cell carcinoma. Int J Radiat Oncol Biol Phys 47:495-501, 2000. (Pubitemid 30236393)
21. Takahashi A, Ohnishi K, Ota I, Asakawa I, Tamamoto T, Furusawa Y, Matsumoto H and Ohnishi T: p53-dependent thermal enhancement of cellular sensitivity in human squamous cell carcinomas in relation to LET. Int J Radiat Biol 77: 1043-1051, 2001. (Pubitemid 32977933)
22. Ohnishi K, Ota I, Takahashi A, Yane K and Ohnishi T: Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck. Apoptosis 7: 367-372, 2002. (Pubitemid 34832261)
23. Takahashi A, Ota I, Tamamoto T, Asakawa I, Nagata Y, Nakagawa H, Kondo N, Ohnishi K, Furusawa Y, Matsumoto H and Ohnishi T: p53-dependent hyperthermic enhancement of tumour growth inhibition by X-ray or carbon-ion beam irradiation. Int J Hyperthermia 19: 145-153, 2003. (Pubitemid 36304683)
24. Stennicke HR and Salvesen GS: Catalytic properties of the caspases. Cell Death Differ 6: 1054-1059, 1999.
25. Kaufmann SH, Desnoyers S, Ottaviano Y, Davidson NE and Poirier GG: Specific proteolytic cleavage of poly (ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis Cancer Res 53: 3976-3985, 1993. (Pubitemid 23267698)
26. Ohnishi T, Matsumoto H, Wang X, Takahashi A, Tamamoto T and Ohnishi K: Restoration by glycerol of p53-dependent apoptosis in cells bearing the mutant p53 gene. Int J Radiat Biol 75: 1095-1098, 1999. (Pubitemid 29468971)
27. Ohnishi T, Ohnishi K, Wang X, Takahashi A and Okaichi K: Restoration of mutant TP53 to normal TP53 function by glycerol as a chemical chaperone. Radiat Res 151: 498-500, 1999. (Pubitemid 29268554)
28. Ohnishi K, Ota I, Takahashi A and Ohnishi T: Glycerol restores p53-dependent radiosensitivity of human head and neck cancer cell bearing mutant p53. Br J Cancer 83: 1735-1739, 2000. (Pubitemid 32001722)
29. Ohnishi K, Ota I, Yane K, Takahashi A, Yuki K, Emoto M, Hosoi H and Ohnishi T: Glycerol as a chemical chaperone enhances radiation-induced apoptosis in anaplastic thyroid carcinoma cells. Mol Cancer 1: No. 4, 2002.