Effect of lipoic acid on the oxidoreductive status of red blood cells in rats subject to oxidative stress by chronic administration of adriamycin

Human and Experimental Toxicology

Volumn 23, Issue 3, 2004, Pages 129-135

  Malarkodi, K P ^a,b   Sivaprasad, R ^a   Varalakshmi, P ^a  

^a UNIVERSITY OF MADRAS   (India)

^b NONE   (India)

Author keywords

Adriamycin; Antioxidants; DL lipoic acid; Erythrocytes; Lipid peroxidation

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; DOXORUBICIN; GLUTATHIONE PEROXIDASE; HEMOGLOBIN; MEMBRANE ENZYME; RETINOL; SUPEROXIDE DISMUTASE; THIOCTIC ACID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BIOCHEMISTRY; BLOOD TOXICITY; BODY WEIGHT; CELL DAMAGE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG CYTOTOXICITY; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME BINDING; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE FRAGILITY; ERYTHROCYTE MEMBRANE; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; HEMOGLOBIN DETERMINATION; LIPID PEROXIDATION; LONG TERM EXPOSURE; MALE; NONHUMAN; OSMOTIC FRAGILITY; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RAT STRAIN; TOXICITY TESTING;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIOXIDANTS; DOXORUBICIN; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; LIPID PEROXIDATION; MALE; OSMOTIC FRAGILITY; OXIDATION-REDUCTION; RATS; RATS, WISTAR; THIOCTIC ACID;

EID: 16544388484     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/0960327104ht428oa     Document Type: Article

References (55)

1. Poggi A, Kornblihtt L, Delaini F, Colombo T, Mussoni L, Reyers I, Donati MB. Delayed hypercoagulability after a single dose of adriamycin to normal rats. Thromb Res Suppl 1979; 16: 639-50.
2. Vaidyanathan S, Boroujerdi M. Interaction of dextrazoxane with red blood cells and hemoglobin alters pharmacokinetics of doxorubicin. Cancer Chemother Pharmacol 2000; 46: 93-100.
3. Mikkelsen RBL, Sun P, Wallach DH. Interaction of adriamycin with human red blood cells. A biochemical and morphological study. J Mol Med 1977; 2: 33-40.
4. Mimnaugh EG, Trush MA, Gram TE. A possible role of membrane lipid peroxidation in anthraycline nephrotoxicity. Biochem Pharmacol 1986; 35: 4327-35.
5. De Atley SM, Aksenov MY, Aksenova MV, Carney JM, Butterfield DA. Adriamycin induces protein oxidation in erythrocyte membrane. Pharmacol Toxicol 1998; 83: 62-68.
6. Lee SK, Lee BM. Oxidation of erythrocyte protein and lipid, and hemolysis in rabbit red blood cells treated with benzo [a] pyrene or adriamycin. J Toxicol Environ Health 1997; 51: 557-69.
7. Bertolatus JA, Klinzman D, Bronsema DA, Ridnour L, Oberley LW. Evaluation of the role of reactive oxygen species in doxorubicin hydrochloride nephrosis. J Lab Clin Med 1991; 118: 435-45.
8. Altorjoy I, Dalmi L, Sari B, Imre S, Balla G. The effect of silibinin (Legabon) on the free radical scavenger mechanisms of human erythrocytes in vitro. Acta Physiol Hung 1992; 80: 375-80.
9. Vilallonga FA, Phillips EW. Interaction of doxorubicin with phospholipid monolayers. J Pharm Sci 1978; 67: 773-75.
10. Goldman R, Facchinetti T, Bach D, Raz A, Shinitzky M. A differential interaction of daunomycin, adriamycin and their derivatives with human erythrocytes and phospholipid bilayers. Biochim Biophys Acta 1978; 512: 254-69.
11. Jansen YMW, Haiten BV, Borm PJA, Mossman BT. Biology of disease. Cell and tissue responses to oxidative damage. Lab Invest 1993; 69: 261-74.
12. Marcello C, Maria V, Luisa T, Antonino B. Vitamin A inhibits doxorubicin-induced membrane lipid peroxidation in rat tissues in vivo. Arch Biochem Biophys 1993; 302: 103-108.
13. Haenen GR, Vermeulen NP, Timmerman H, Bast A. Effect of thiols on lipid peroxidation in rat liver microsomes. Chem Biol Interact 1989; 71: 201-12.
14. Sumathi R, Kalpana Devi V, Varalakshmi P. DL-α-lipoic acid protection against cadmium induced tissue lipid peroxidation. Med Sci Res 1994; 22: 23-25.
15. Packer L, Witt EH, Tritschler HJ. Alpha-lipoic acid as a biological antioxidant. Free Radic Biol Med 1995; 19: 227-50.
16. Balachandar AV, Malarkodi KP, Varalakshmi P. Protective role of DL-α-lipoic acid against adriamycin induced cardiac lipid peroxidation. Hum Exp Toxicol 2003; 22: 249-54.
17. Malarkodi KP, Balachandar AV, Varalakshmi P. Protective effects of lipoic acid on adriamycin induced lipid peroxidation in rat kidney. Mol Cell Biochem 2003; 247: 9-13.
18. Dodge JT, Mitchell G, Hanahan DT. The preparation and chemical characteristics of haemoglobin-free ghosts of human erythrocytes. Arch Biochem Biophys 1963; 100: 119-30.
19. Quist EH. Regulation of erythrocyte membrane shape by calcium ion. Biochim Biophys Res Commun 1980; 92: 631-37.
20. Beutler E. Red cell metabolism. A manual of biochemical methods, third edition. Orlando, FL: Grune and Stratton, 1984.
21. Drabkin DLR, Austin TH. Spectrophotometric studies, spectrophotometric constants for Haemoglobin derivatives in human, dog and rabbit blood. J Biol Chem 1932; 98: 718-33.
22. Wintrobe MM. Macroscopic examination of the blood. Am J Med Sci 1933; 135: 58.
23. King J. The transferases - alanine and aspartate transaminases. In Van D ed. Practical clinical enzymology. London: Norstrand Company Limited, 1965: 121-38.
24. Lowry OH, Rosebrough NJ, Farr AI, Randall RJ. Protein measurement with the folin-phenol reagent. J Biol Chem 1951; 193: 265-75.
25. Devasagayam TP. Lipid peroxidation in rat uterus. Biochim Biophys Acta 1986; 76: 507-14.
26. Marklund S, Marklund G. Involvement of superoxide anion radical in auto oxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974; 47: 469-74.
27. Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hajeman DG, Hoekstra WG. Selenium biochemical role as a component of glutathione purification and assay. Science 1973; 179: 588-90.
28. Omaye ST, Turnball JD, Sauberlich HE. Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. Meth Enzymol 1971; 62: 1-11.
29. Desai ID. Vitamin E analysis methods for animal tissues. Meth Enzymol 1984; 105: 138-47.
30. Bayfield HT, Cole EA. Colorimetric estimation of vitamin A with trichloro acetic acid. Meth Enzymol 1974; 67: 189-95.
31. Bonting SL. Sodium-potassium activated adenosine triphosphatase and cation transport. In Bittar EE ed. Membrane ion transport. England: Wiley Interscience, 1970: 257-63.
32. Ohnishi T, Suzuki T, Ozawas K. A comparative study of plasma membrane magnesium ion ATPase activities in normal, regenerating and malignant cells. Biochim Biophys Acta 1982; 684: 67-74.
33. Hjertan S, Pan H. Purification and characterisation of two forms of a low affinity calcium ion ATPases from erythrocyte membrane. Biochim Biophys Acta 1983; 755: 457-66.
34. Usha R, Swaroop KS. Special hematological tests. In Mukherjee KL ed. Medical laboratory technology, a procedure manual for routine diagnostic tests, Volume I. New Delhi: Tata McGraw Hill, 1988: 308-46.
35. Doll DC, Weiss RB. Hemolytic anemia associated with antineoplastic agents. Cancer Treat Rep 1985; 69: 777-82.
36. Chiu D, Lubin B, Shohet SB. Peroxidative reactions in red cell biology. In Pryor WP ed. Free radicals in biology, Volume V. New York: Academic Press, 1982: 115-53.
37. Shinohara K, Tanaka KR The effects of adriamycin (doxorubium HCl) on human red blood cells. Hemoglobin 1980; 4: 735-45.
38. Henderson CA, Metz EN, Balcerzak SP, Sagone AL Jr. Adriamycin and daunomycin generate reactive oxygen compounds in erythrocytes. Blood 1978; 52: 878-85.
39. Winterbourn CC, French JK, Claridge RFC. Superoxide dismutase as an inhibitor of reactions of semiquinone radicals. FEBS Lett 1978; 94: 269-72.
40. Herman EH, Zang J, Hasinoff BB, Chackoick DP, Clark JR Jr, Ferrans VJ. Comparison of the protective effects against chronic doxorubicin toxicity and the rate of iron (III) displacement reaction of ICRF-187 and other bisdiketo piperazene. Cancer Chemother Pharmacol 1997; 40: 400-408.
41. Bertani T, Poggi A, Pozzoni B, Delaini F, Sacchi G, Thoua Y, Mecca G, Remuzzi G, Donati MB. Adriamycin-induced nephrotic syndrome in rats. Lab Invest 1982; 46: 16-23.
42. Carrel RW, Winterbourn CC, Rachmilewits EA. Activated oxygen and hemolysis. Br J Haematol 1975; 30: 259-64.
43. Herman EH, El-Hage A, Ferrans VJ. Protective effects of ICRF-187 on doxorubicin-induced cardiac and renal toxicity in spontaneously hypertensive (SHR) and normotensive (WKY) rats. Toxicol Appl Pharmacol 1988; 92: 42-53.
44. Thabrew MI, Samarawickrema NA, Chandrasena LG, Jayasekera S. Protection by garlic against adriamycin-induced alterations in the oxido-reductive status of mouse red blood cells. Phytother Res 2000; 14: 215-17.
45. Svadlenka I, Davidkova E, Rosmus J. Interaction of MDA with collagen. Z Lebensm Unters Forsch 1975; 157: 263-68.
46. Malarkodi KP, Balachandar AV, Varalakshmi P. The influence of lipoic acid on adriamycin-induced hyperlipidemic nephrotoxicity in rats. Mol Cell Biochem 2003; 247: 139-45.
47. Scholich H, Murphy ME, Sies H. Antioxidant activity of dihydrolipoate against microsomal lipid peroxidation and its dependence of α-tocopherol. Biochim Biophys Acta 1989; 1001: 256-61.
48. Constantinescu A, Han D, Packer L. Vitamin E recycling in human erythrocyte membranes. J Biol Chem 1992; 268: 10906-13.
49. Constantinescu A, Tritschler H, Packer L. α-Lipoic acid protects against hemolysis of human erythrocytes induced by peroxyl radicals. Biochem Mol Biol Int 1994; 33: 669-79.
50. Biewenga GP, Haenen GR, Bast A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol 1997; 29: 315-31.
51. + pump ATPase of human red blood cell membrane. Biochem Pharmacol 1993; 46: 525-34.
52. Schioppocassi G, Schwartz HS. Membrane actions of daunorubicin in mammalian erythrocytes. Res Commun Chem Pathol Pharmacol 1977; 18: 519-29.
53. Miura T, Muraoka S, Ogiso T. Adriamycin-Fe(3+)-induced inactivation of enzymes in erythrocyte membranes during lipid peroxidation. Res Commun Mol Pathol Pharmacol 1995; 87: 133-43.
54. 2+-ATPase by activated oxygen through thiol and lipid-dependant mechanisms. Biochim Biophys Acta 1986; 862: 8-16.
55. Morgan WA, Kaler B, Bach PH. The role of reactive oxygen species in adriamycin and menadione-induced glomerular toxicity. Toxicol Lett 1998; 94: 209-15.