Caregiver Burden in Alzheimer's Disease

Consultant Pharmacist

Volumn 19, Issue 4, 2004, Pages 352-362

  Slattum, Patricia W ^a   Johnson, Mary Ann ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b ALZHEIMER'S ASSOCIATION   (United States)

Author keywords

Alzheimer's disease; Caregiver burden; Medications

Indexed keywords

CHOLINESTERASE INHIBITOR; CITALOPRAM; DONEPEZIL; GALANTAMINE; HALOPERIDOL; MEMANTINE; RISPERIDONE; RIVASTIGMINE; TRAZODONE;

ALZHEIMER DISEASE; CAREGIVER; CAREGIVER BURDEN; CLINICAL TRIAL; COMMUNITY CARE; COUNSELING; DAILY LIFE ACTIVITY; DRUG EFFICACY; DRUG INFORMATION; EDUCATION; FAMILY THERAPY; HOME CARE; HUMAN; INSTRUMENTAL DAILY LIFE ACTIVITY; MEASUREMENT; PHARMACEUTICAL CARE; PHARMACIST; PREDICTION; PSYCHOPHARMACOTHERAPY; QUALITY OF LIFE; REVIEW; SOCIAL SUPPORT; STRESS; VOLUNTEER;

EID: 16544386796     PISSN: 08885109     EISSN: None     Source Type: Journal    
DOI: 10.4140/TCP.n.2004.352     Document Type: Review

References (48)

1. Langa KM, Chernew ME, Kabeto MU et al. National estimates of the quantity and cost of informal caregiving for the elderly with dementia. J Gen Intern Med 2001;16:770-8.
2. http://www.alz.org/ResourceCenter/FactSheets/FSAlzheimerStats.pdf. Accessed December 2, 2003.
3. Ernst RL, Hay JW. The U.S. economic and social costs of Alzheimer's disease revisited. Am J Public Health 1994;84:1261-4.
4. Schulz R, O'Brien AT, Bookwala J et al. Psychiatric and physical morbidity effects of dementia caregiving: prevalence, correlates, and causes. Gerontologist 1995;35:771-91.
5. Nayak RA, Mulchandani D. Dementia caregiving: who will care for our caregivers? Drug Benefit Trends 2003;15:39-49.
6. Rabins P, Mace N, Lucas M. The impact of dementia on the family. JAMA 1982;248:333-5.
7. Moritz DJ, Kasl SV, Ostfeld AM. The health impact of living with a cognitively impaired elderly spouse. J Aging Health 1992;4:244-67.
8. George LK, Gwyther LP. Caregiver well-being: a multidimensional examination of family caregivers of demented adults. Gerontologist 1986;26:253-9.
9. Vitaliano PP, Young HM, Russo J et al. Does expressed emotion in spouses predict subsequent problems among care recipients with Alzheimer's disease? J Geriatr 1993;48:202-9.
10. Dunkin JJ, Anderson-Hanley C. Dementia caregiver burden: a review of the literature and guidelines for assessment and intervention. Neurology 1998;51(suppl 1):s53-s60.
11. Max W, Webber P, Fox P. Alzheimer's disease: the unpaid burden of caring. J Aging Health 1995;7:179-99.
12. Bedard M, Pedlar D, Martin NJ et al. Burden in caregivers of cognitively impaired older adults living in the community: methodological issues and determinants. Int Psychogeriatr 2000;12:307-32.
13. Clyburn LD, Stones MJ, Hadjistavropoulos T et al. Predicting caregiver burden and depression in Alzheimer's disease. J Gerontol B Psychol Sci Soc Sci 2000;55:s2-s13.
14. Colerick EJ, George LK. Predictors of institutionalization among caregivers of patients with Alzheimer's disease. J Am Geriatr Soc 1986;34:493-8.
15. Zarit SH, Reever KE, Bach-Peterson J. Relatives of the impaired elderly: correlates of feelings of burden. Gerontology 1980;20:649-55.
16. Townsend A, Noelker L, Deimling G et al. Longitudinal impact of interhousehold caregiving on adult children's mental health. Psychol Aging 1989;4:393-401.
17. Schulz R, Williamson GM. The measurement of caregiver outcomes in Alzheimer disease research. Alz Dis Assoc Disorder 1997;11(suppl 6):s117-s24.
18. Farcnik K, Persyko MS. Assessment, measures and approaches to easing caregiver burden in Alzheimer's disease. Drugs Aging 2002;19:203-15.
19. Vitaliano PP, Young HM, Russo J. Burden: a review of measures used among caregivers of individuals with dementia. Gerontologist 1991;31:67-75.
20. Vitaliano PP, Russo J, Young HM et al. The screen for caregiver burden. Gerontology 1991;31:76-83.
21. Kinney JM, Stephens MAP. Caregiver hassles scale: assessing the daily hassles of caring for a family member with dementia. Gerontology 1991;31:328-32.
22. Novak M, Guest CI. Application of a multidimensional caregiver burden inventory. Gerontology 1989;29:798-803.
23. Davis KL, Marie DB, Kane R et al. The caregiver activity survey (CAS): development and validation of a new measure for caregivers of persons with Alzheimer's disease. Int J Geriatr Psychiatry 1997;12:978-88.
24. Kaufer DI, Cummings JL, Christine D et al. Assessing the impact of neuropsychiatric symptoms in Alzheimer's disease: the neuropsychiatric inventory caregiver distress scale. J Am Geriatr Soc 1998;46:210-5.
25. Pearlin LI, Mullan JT, Semple SJ et al. Caregiving and the stress process: an overview of concepts and their measures. Gerontologist 1990;30:583-94.
26. Wimo A, Weterholm AL, Mastey V et al. Evaluation of the healthcare resource utilization and caregiver time in antidementia drug trials. In: Wimo A, Jonsson B, Karlsson G, Winblad B, eds. Health economics of dementia. Chichester, UK: John Wiley; 1998:465-99.
27. Mahoney DF, Jones RN, Coon DW et al. The Caregiver Vigilance Scale: application and validation in the Resources for Enhancing Alzheimer's Caregiver Health (REACH) project. Am J Alzheimers Dis Other Demen 2003;18:39-48.
28. Chpp EC, Moore MJ. Caregiver time use: an outcome measure in clinical trial research on Alzheimer's disease. Clin Pharmacol Ther 1995;58:228-36.
29. Wimo A, Winblad B, Grafstrom M, The social consequences for families with Alzheimer's disease patients: potential impact of new drug treatment. Int J Geriatr Psychiatry 1999;14:338-47.
30. Levy ML, Cummings JL, Kahn-Rose R. Neuropsychiatric symptoms and cholinergic therapy for Alzheimer's disease. Gerontology 1999; 45:(suppl):s15-s22.
31. Potkin SG. The ABC of Alzheimer's disease: ADL and improving day-to-day functioning of patients. Int Psychogeriatr 2002;14(suppl):s7-s26.
32. Feldman H, Gauthier S, Hecker J et al. Efficacy of donepezil on maintenance of activities of daily living in patients with moderate to severe Alzheimer's disease and the effect on caregiver burden. J Am Geriatr Soc 2003;51:737-44.
33. Fillit HM, Gutterman EM, Brooks RL. Impact of donepezil on caregiving burden for patients with Alzheimer's disease. Int Psychogeriatr 2000;12:389-401.
34. Birks J, Grimley EJ, Iakovidou V et al. Rivastigmine for Alzheimer's disease. Cochran Review. In: Cochran Library, Issue 4, 2001.
35. Gabelli C. Rivastigmine: an update on therapeutic efficacy in Alzheimer's disease and other conditions. Curr Med Res Opin 2003;19:69-82.
36. Hauber AB, Gnanasakthy A, Mauskopf JA. Savings in the cost of caring for patients with Alzheimer's disease in Canada: an analysis of treatment with rivastigmine. Clin Ther 2000;22:439-51.
37. Moretti R, Torre P, Antonello RM et al. Rivastigmine in subcortical vascular dementia: a comparison trial on efficacy and tolerability for 12 months follow-up. Eur J Neurol 2001;8:361-2.
38. Sano M, Wilcock GK, van Baelen B et al. The effects of galantamine treatment on caregiver time in Alzheimer's disease. Int J Geriatr Psychiatry 2003;18:942-50.
39. Wilcock G, Howe I, Coles H et al. A long-term comparison of galantamine and donepezil in the treatment of Alzheimer's disease. Drugs Aging 2003;20:777-89.
40. Blesa R. Galantamine: therapeutic effects beyond cognition. Dement Geriatr Cogn Disord 2000;11:28-34.
41. Reisberg B, Doody R, Stoffler A et al. Memantine in moderate-to-severe Alzheimer's disease. N Engl J Med 2003;348:1333-41.
42. Teri L, Logsdon RG, Peskind E et al. Treatment of agitation in AD: a randomized, placebo-controlled clinical trial. Neurology 2000;55:1271-8.
43. Shigenobu K, Ikeda M, Fukuhara R et al. Reducing the burden of caring for Alzheimer's disease through the amelioration of 'delusions of theft' by drug therapy. Int J Geriatr Psychiatry 2002;17:211-7.
44. Moretti R, Torre P, Antonello RM et al. Depression and Alzheimer's disease: symptom or comorbidity. Am J Alzheimers Dis Other Demen 2002;17:338-44.
45. Goad DL, Davis CM, Liem P et al. The use of selegiline in Alzheimer's patients with behavior problems. J Clin Psychiatry 1991;52:342-5.
46. Brodaty H, Green A, Koschera A. Meta-analysis of psychosocial interventions for caregivers of people with dementia. J Am Geriatr Soc 2003;51:657-64.
47. Ranelli PL, Aversa SL. Medication-related stressors among family caregivers. Am J Hosp Pharm 1994;51:75-9.
48. Travis SS, Bernard MA, McAuley W et al. Development of the Family Caregiver Medication Administration Hassles Scale. Gerontologist 2003;43:360-8.