Pharmacokinetic modeling of species-dependent enhanced bioavailability of trifluorothymidine by thymidine phosphorylase inhibitor.

Drug metabolism and pharmacokinetics

Volumn 19, Issue 3, 2004, Pages 206-215

  Tsuchiya, Hiroyuki ^a   Kuwata, Keizou ^a   Nagayama, Sekio ^a   Yamashita, Kazumasa ^a   Kamiya, Hiroyuki ^a   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DERIVATIVE; ENZYME INHIBITOR; TAS 102; THYMIDINE PHOSPHORYLASE; TRIFLURIDINE; URACIL;

ANIMAL; ARTICLE; BIOAVAILABILITY; BIOLOGICAL MODEL; COMPARATIVE STUDY; COMPUTER SIMULATION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG COMBINATION; MACACA; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; RAT; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENZYME INHIBITORS; MACACA FASCICULARIS; MALE; MODELS, BIOLOGICAL; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY; THYMIDINE PHOSPHORYLASE; TRIFLURIDINE; URACIL;

EID: 16544372827     PISSN: 13474367     EISSN: None     Source Type: Journal    
DOI: 10.2133/dmpk.19.206     Document Type: Article

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