Efficacy of brown seaweed hot water extract against Hcl-ethanol induced gastric mucosal injury in rats

Archives of Pharmacal Research

Volumn 27, Issue 4, 2004, Pages 449-453

  Raghavendran, Hanumantha Rao Balaji ^a   Sathivel, Arumugam ^a   Devaki, Thiruvengadam ^a,b  

^a UNIVERSITY OF MADRAS   (India)

^b NONE   (India)

Author keywords

Antioxidants; Gastric injury; Gastric mucosa; HCl ethanol; Lipid peroxides; Sargassum polycystum

Indexed keywords

ALCOHOL; HYDROCHLORIC ACID; PLANT EXTRACT; WATER;

ANIMAL; ARTICLE; COMPARATIVE STUDY; DRUG EFFECT; HEAT; ISOLATION AND PURIFICATION; MALE; PATHOLOGY; RAT; SARGASSUM; STOMACH MUCOSA; STOMACH ULCER; WISTAR RAT;

ANIMALS; ETHANOL; GASTRIC MUCOSA; HEAT; HYDROCHLORIC ACID; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR; SARGASSUM; STOMACH ULCER; WATER;

EID: 16544371238     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02980088     Document Type: Article

References (37)

1. Abdussalam, S., Drugs from seaweeds. Med. Hypo., 32, 33-35 (1990).
2. Anggardiredja, J., Andyani, R., and Muaswanah, H., Antioxidant activity of Sargassum polycystum C.Ag. and laurencia obtusa from seribu islands. J. App. phycol., 9, 477-479 (1997).
3. Anson, M. L., The estimation of pepsin, trpsin, papain and cathepsin with hemoglobin. J. Gen. physiol., 22, 79-89 (1938)
4. Bobbin dubigcon, C., Hoebler, C., Lognone, V., Dagorn-Scaviner, C., Mabeau, S., Barry, J. L., and Lahaye, M., Chemical composition physicochemical properties enzymatic inhibition and fermentative characteristics of dietary fibers from edible seaweeds. Sci. Aliments, 17, 619-639 (1997).
5. Chacin, J., Peptic ulcer a failure of the defence mechanisms of gastro duodenal mucosa. Gen., 44,163-170 (1990).
6. Chapman, V. J. and Chapman, D. J., Seaweeds and their uses Chapman and Hall London, (1980).
7. Davenport, H. W., Salicylate damage to the gastric mucosal barrier. N. Engl. J. Med., 276, 1307-1312 (1967)
8. Dayton, M, T., Kauffman, G. L., and Schlegel, J. F., Gastric bicarbonate appearance with ethanol ingestion Mechanism and significance. Dig. Dis. Sci., 28, 449-455 (1983).
9. th edition, Ed. By Haubrich K Roth Schattner Vol 2, p. 897 (1985).
10. Ellman, G. L., Tissue sulfhydryl groups. Arch. Biochem. Biophys., 82, 70-77 (1959).
11. Glavin, G. B. and Szabo, S., Experimental gastric mucosal injury laboratory models reveal mechanism of pathogenesis and new therapeutic strategies. FASEB J., 6, 825-831 (1992).
12. nd edition. Elsevier, Amsterdam, (1972).
13. Guth, P. H., Paulsen, G. E., and Nagata, H., Histological and microcirculatory changes in alcoholinduced gastric lesions in the rat Effect of prostaglandin cytoprotection. Gastroenterology., 87, 1083-1090 (1984).
14. Habig, W. H ., Pabst, M. J., and Jakoby, W. B., Glutathion- s-transferase: the first enzymatic step in mercapturic acid formation. J. Biol. Chem., 249, 71130-71139 (1974).
15. Hara, N., Okabe, S., and Takagi K.-A., Effects of gefarnate on acute gastric lesions in rats Folia. Pharmacology. Jpn., 85, 443 (1985).
16. Hoppe, H. A. and Lerving, T., Marine algae in pharmaceutical science vol 2 (Walter de Gruyter, Berlin), pp 3-48 (1982).
17. Inoue, M., Satio, Y., Hirato, E., Morino, Y., and Nagase, S., Regulation of redox status of plasma proteins by metabolism and transport of glutathione and related compounds. J. Protein Chem., 6, 207-225 (1987).
18. Jothi saraswathi, S., Babu, B., and Rengaswamy R., Seasonal studies on the alginate and its biochemical composition I: Sargassum polycystum (Fucales), phaeophyceae. Phycological research, 51(4), 240 (2003).
19. Juhani, P., Effect of ethanol on peptic activity in the rat stomach. Digestion, 23, 97-103 (1982)
20. Kloareg, B. and Quatrano, R. S., Structure of the cell walls of marine algae and ecophysiological functions of the matrix polysaccharide. Ocenanogr. Mar. Boil. Annu. Rev., 26, 259-315 (1988).
21. Lahaye, M. and Kaeffer, B., Seaweed dietary fibers structure physicochemical and biological properties relevant to intestinal physiology. Sci. Aliments., 17, 563-584 (1997).
22. Lowry, O. H., Rosenborough, N. I., Farr, A. I., and Randall, R. J., Protein measurement with folin phenol reagent., J. Biol. Chem., 193, 265-275 (1951).
23. Mc Guigan, J. E., Peptic ulcer in Harrison's principles of internal medicine, 13th edition ed by Kurt J I Eugene B margin J B Wilson J D and Karper D L Vol 2, 1363 (1994).
24. Misra, H. P. and Fridovich, I ., The role of superoxide anion in the auto- oxidation of epinephrine and a simple assay for superoxidedismutase. J. Biol. Chem., 247, 170-3175 (1972).
25. Morenkova, S.-A., Tabutsadze, T. U., Fedorova, L. M., and Masenko, N. P., Effect of ulcerogenic agent cysteamine or the content of glutathione and GSH-dependent enzymes in the mucous membrane of the gastro duodenal region in the rat. Biull. Eksp. Biol. Med., 104, 570-572 (1987).
26. Nagaoka, M., Shibata, H., Kimura-Takagi, I., Hashimoto, S., Aiyama, R., Ueyama, S., and Yokokura, T., Anti-ulcer effects and biological activities of polysaccharide from marine algae. Biofactors, 12 (1-4), 267-274 (2000).
27. Ohakawa, H., Ohishi, N., and Yagi, K., Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem., 95, 351-358 (1979)
28. Paglia, D. E. and Valentaine, W. N., Studies on the glutathione and glutathione characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med., 70, 158-169 (1967).
29. Pihan, G., Rigello, C., and Szabo, S., Free radicals and lipid peroxidation in ethanol and aspirininduced gastric mucosal injury. Dig. Dis. Sci., 32 1395-1401 (1987)
30. Piper, D. W. and Stiel, D., Pathogenesis of chronic peptic ulcer, current thinking and clinical implications. Med. Proc., 2, 7-10 (1986).
31. Takahara, S., Hamiliton, B. H., Nell, J. V., Kobra, T. Y., Ogura, Y., and Nishimura, E. T., Hypocatalasemia A new genetic carrier state. J. Clin. Invest., 29, 610-619 (1960).
32. Takeuchi, K., Okabe, S., and Takagi, K., A new model of stress ulcers in the rat with pylorus ligation and its pathogenesis. Am. J. Dig. Dis., 21, 782-788 (1976).
33. Tappel, A. L., Lipid peroxidation damage to cell components. Fed. Proc., 32, 1870-1874 (1973).
34. Warren, L., The thiobarbituric acid assay of sialic acid. J. Biol. Chem., 234, 1971-1975 (1959).
35. Winzler, R. J., Determination of serum glycoprotein. Methods Biochem. Anal ., 2, 279-311 (1958).
36. Wormsley, K. G., The pathophysiology of duodenal ulceration. Gut, 15, 59-64 (1974).
37. Yoshikewa, T., Naito, Y., Kishi, A., Tomii, T., Kaneko, T., Linuma, S., Ichikawa, H., Yasuda, M., Takahashi, S., and Kondo, M., Role of active oxygen, lipid peroxidation and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats. Gut, 34, 732-737 (1993).