Treatment of infected tibial nonunions with debridement, antibiotic beads, and the Ilizarov method

Military Medicine

Volumn 169, Issue 9, 2004, Pages 728-734

  McHale, Kathleen A ^a   Ross, Amy E ^a  

^a WALTER REED ARMY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; POLY(METHYL METHACRYLATE); TOBRAMYCIN; ANTIINFECTIVE AGENT;

ADULT; ANTIBIOTIC BEAD; ARTICLE; BACILLUS SUBTILIS; BONE RESECTION; BONE TRANSPLANTATION; CLINICAL ARTICLE; CLOSTRIDIUM PERFRINGENS; COMPRESSION; DEBRIDEMENT; DRUG DELIVERY SYSTEM; FEMALE; FRACTURE EXTERNAL FIXATION; FRACTURE NONUNION; HUMAN; ILIZAROV TECHNIQUE; INFECTION COMPLICATION; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MUSCLE WEAKNESS; OSTEOARTHRITIS; OSTEOTOMY; RECURRENT DISEASE; STAPHYLOCOCCUS AUREUS; TIBIA FRACTURE; CASE REPORT; MICROBIOLOGY; MILITARY MEDICINE; OPEN FRACTURE; SOLDIER;

ADULT; ANTI-BACTERIAL AGENTS; DEBRIDEMENT; FEMALE; FRACTURES, OPEN; FRACTURES, UNUNITED; HUMANS; ILIZAROV TECHNIQUE; MALE; MILITARY MEDICINE; MILITARY PERSONNEL; TIBIAL FRACTURES;

EID: 16544367203     PISSN: 00264075     EISSN: None     Source Type: Journal    
DOI: 10.7205/MILMED.169.9.728     Document Type: Article

References (19)

1. Gustilo RB, Andserson JT: Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analysis. J Bone Joint Surg Am 1976; 58: 453-8.
2. Tetsworth K, Cierny G III: Osteomyelitis debridement techniques. Clin Orthop 1999; 360: 87-96.
3. Cierny G III: Infected tibial nonunions (1981-1995): the evolution of change. Clin Orthop 1999; 360: 97-105.
4. Pateakis MJ, et al: Culture results in open wound treatment with muscle transfer for tibial osteomyelitis. Clin Orthop 1999; 360: 66-70.
5. Swiontkowski MF, et al: A comparison of short- and long-term intravenous antibiotic therapy in the postoperative management of adult osteomyelitis. J Bone Joint Surg Br 1999; 81: 1046-50.
6. Keating JF, et al: Reamed nailing of open tibial fractures: does the antibiotic bead pouch reduce the deep infection rate? J Orthop Trauma 1996; 10: 298-303.
7. Henry SL, Ostermann PA, Seligson D: The antibiotic bead pouch technique. Clin Orthop 1993; 295: 54-62.
8. Ostermann PA, Henry SL, Seligson D: The effect of local antibiotic therapy on the prevention of infection in open fractures. 1996; 32: 230-4.
9. Bowyer GW: Antibiotic impregnated beads in open fractures: a report on the technique and possible applications in military surgery. J R Army Med Corps 1993; 139: 100-4.
10. Alonge TO, Wale A: Intra-operative antibiotic bead maker: point of technique. Afr J Med Med Sci 1999; 28: 193-4.
11. Walenkamp GH, Kleijn LL, deLeeuw M: Osteomyelitis treated with gentamicin-PMMA beads: 100 patients followed for 11-12 years. Acta Orthop Scand 1998; 69: 518-22.
12. Ueng SW, Wei FC, Shih CH: Management of femoral diaphyseal infected non-union with antibiotic beads local therapy, external skeletal fixation, and staged bone grafting. J Trauma 1999; 46: 97-103.
13. Calhoun JH, et al: The Ilizarov fixator and polymethylmethacrylate- antibiotic beads for the treatment of infected deformities. Clin Orthop 1993; 295: 13-22.
14. Wiss DA, Johnson DL, Miao M: Compression plating for non-union after failed external fixation of open tibial fractures. J Bone Joint Surg Am 1992; 74: 1279-85.
15. Sledge SL, et al: Intramedullary nailing with reaming to treat non-union of the tibia. J Bone Joint Surg Am 1989; 71: 1004-19.
16. Maini L, et al: The Ilizarov method in infected nonunion of fractures. Injury 2000; 31: 509-17.
17. Thirumal M, Shong HK: Bone transport in the management of fractures of the tibia. Med J Malaysia 2001; 56: 44-52.
18. Chan YS, et al: Management of small infected tibial defects with antibiotic-impregnated autogenic cancellous bone grafting. J Trauma 1998; 45: 758-64.
19. Meyer JD, et al: Preparation and in vitro characterization of gentamycin-impregnated biodegradable beads suitable for treatment of osteomyelitis. J Pharm Sci 1998; 87: 1149-54.