Diethylstilbestrol exposure in utero: A paradigm for mechanisms leading to adult disease

Birth Defects Research Part A - Clinical and Molecular Teratology

Volumn 73, Issue 3, 2005, Pages 133-135

  Mericskay, Mathias ^a   Carta, Luca ^a   Sassoon, David ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYLSTILBESTROL; ESTROGEN RECEPTOR; PROTEIN WNT7A; UNCLASSIFIED DRUG; WNT PROTEIN;

CONFERENCE PAPER; EMBRYO DEVELOPMENT; FETUS; GENE DISRUPTION; GENETIC ANALYSIS; GENITAL MALFORMATION; HUMAN; MOUSE; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UTERUS MALFORMATION; VAGINA DISEASE;

ANIMALS; DIETHYLSTILBESTROL; ENDOMETRIUM; ESTROGENS, NON-STEROIDAL; FEMALE; MICE; NEOPLASMS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTO-ONCOGENE PROTEINS; WNT PROTEINS;

EID: 16444376498     PISSN: 15420752     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdra.20121     Document Type: Conference Paper

References (5)

1. Hatch EE, Palmer JR, Titus-Ernstoff L, et al. 1998. Cancer risk in women exposed to diethylstilbestrol in utero. JAMA 280:630-634.
2. Miller C, Sassoon DA. 1998. Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract. Development 125:3201-3211.
3. Miller C, Pavlova A, Sassoon D. 1998a. Differential expression patterns of Wnt genes in the murine female reproductive tract during development and the estrous cycle. Mech Dev 76:91-99.
4. Miller C, Degenhardt K, Sassoon DA. 1998b. Fetal exposure to DES results in de-regulation of Wnt-7a during a critical period of uterine morphogenesis. Nat Gen 20:228-230.
5. Mittendorf R, Herbst AL. 1994. DES exposure: an update [Review]. Contemp Pediatr 11:59-62, 64, 66 passim.