Chemical gels of scleroglucan obtained by cross-linking with 1,ω-dicarboxylic acids: Synthesis and characterization

Journal of Drug Delivery Science and Technology

Volumn 15, Issue 2, 2005, Pages 145-150

  Casadei, M A ^a   Pitarresi, G ^b   Benvenuti, F ^a   Giannuzzo, M ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

Author keywords

1 dicarboxylic acid; Controlled release; Cross linking reaction; Hydrogel; Scleroglucan

Indexed keywords

1,OMEGA DICARBOXYLIC ACID; CARBON; DICARBOXYLIC ACID DERIVATIVE; POLYMER; SCLEROGLUCAN; THEOPHYLLINE; UNCLASSIFIED DRUG;

ARTICLE; ATOM; CALCULATION; CROSS LINKING; DIFFUSION COEFFICIENT; DRUG RELEASE; GEL; REACTION ANALYSIS; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE FORMULATION; SUSTAINED RELEASE PREPARATION; SYNTHESIS; TABLET FORMULATION;

EID: 16444372501     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1773-2247(05)50019-4     Document Type: Article

References (15)

1. DE NOOY A.E.J., RORI V., MASCI G., DENTINI M., CRESCENZI V. - Synthesis and preliminary characterisation of charged derivatives and hydrogels from scleroglucan. - Carbohydr. Res., 324, 116-226, 2000.
2. TOUITOU E., ALHAIQUE F., RICCIERI F.M., RICCIONI G., SANTUCCI E. - Scleroglucan as sustained release oral preparations. Part I. In vitro experiments. - Drug Des. Delivery, 5, 141-148, 1989.
3. ALHAIQUE F., BELTRAMI E., RICCIERI F.M., SANTUCCI E., TOUITOU E. - Scleroglucan sustained release oral preparations. Part II. Effects of additives. - Drug Des. Delivery, 5, 249-257, 1989.
4. ALHAIQUE F., CARAFA M., RICCIERI F.M., SANTUCCI E., TOUITOU E. - Studies on the release behaviour of a polysaccharide matrix.- Pharmazie, 48, 432-435, 1993.
5. RIZK S., DURU C., GAUDY D., JACOB M., FERRARI F., BERTONI M., CARAMELLA C. - Physicochemical characterisation and tabletting properties of scleroglucan. - Int. J. Pharm., 112, 125-131, 1994.
6. CRESCENZI V., DENTINI M., SILVI F., PACI M., PARADOSSI G., BELLINI L.D., RIGHETTO Z. - Case studies of physical and chemical gels based on microbial polysaccharides.- Bioactive and Compatible Polymers, 10, 235-248, 1995.
7. CRESCENZI V., DENTINI M., IMBRIACO D., LAREZ-VELASQUEZ C., CIFERRI A. - Novel types of polysaccharidic assemblies. - Macromol. Chem. Phys., 196, 2873-2880, 1995.
8. COVIELLO T., DENTINI M., RAMBONE G., DESIDERI P., CARAFA M., MURTAS E., RICCIERI F.M., ALHAIQUE F. - A novel co-cross-linked polysaccharide: studies for a controlled delivery matrix. - J. Controlled Rel., 55, 57-66, 1998.
9. COVIELLO T., GRASSI M., RAMBONE G., SANTUCCI E., CARAFA M., MURTAS E., RICCIERI F.M., ALHAIQUE F. - Novel hydrogel system from scleroglucan: synthesis and characterisation. - J. Controlled Rel., 60, 367-378, 1999.
10. COVIELLO T., GRASSI M., RAMBONE G., ALHAIQUE F. - A cross-linked system from scleroglucan derivative: preparation and characterisation. - Biomaterials, 22, 1899-1909, 2001.
11. ALHAIQUE F., CASADEI M.A., COVIELLO T., MICHELETTI MORACCI F. - Chemical gel of scleroglucan for controlled release formulations. - Acta Tecnologiae et Legis Medicamenti, 2, 185-90, 2001.
12. GIANNI R., DELBEN F., LIUT G., BERNSTORF S., AMENITSCH H., RIZZO R. - Synthesis and conformational properties of cyanoethyl-scleroglucan. - Carbohydr. Pol., 47, 387-391, 2002.
13. GIAMMONA G., PITARRESI G., CAVALLARO G., BUSCEMI S., SAIANO F. - New biodegradable hydrogels based on a photocross-linkable modified polyaspartamide. Synthesis and characterisation. - Biochim. Biophys. Acta, 1428, 29-38, 1999.
14. GIAVASIS I., HARVEY L.M., MCNEIL B. - Scleroglucan - In: Biopolymers, Wiley-VCH Verlag GmbH, Weinheim, Germany, 2002, pp. 37-60.
15. CRESCENZI V., DENTINI M., SEGATORI M., TIBLANDI C., CALLEGARO L., BENEDETTI L. - Synthesis and preliminary characterisation of new esters of the bacterial polysaccharide gellan. - Carbohydr. Res., 231, 73-81, 1992.