Water-soluble prodrugs of cyclosporine A with tailored conversion rates

Journal of Peptide Research

Volumn 65, Issue 3, 2005, Pages 364-374

  Hamel, A R ^a   Hubler, F ^a   Mutter, Manfred ^a  

^a EPFL   (Switzerland)

Author keywords

Conversion rates; Cyclosporine A; Drug delivery; Enzyme triggered release; Prodrugs; Solubilization

Indexed keywords

3 HYDROXY 4 METHYL 2 METHYLAMINO 6 OCTENOIC ACID; CYCLOPHILIN A; CYCLOSPORIN A; CYCLOSPORIN DERIVATIVE; PRODRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DRUG BINDING; DRUG DEGRADATION; DRUG PURITY; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME RELEASE; ENZYME STABILITY; EVALUATION; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PRODUCT RECOVERY; RAT;

ANIMALS; BIOTRANSFORMATION; CYCLOSPORINE; IMMUNOSUPPRESSIVE AGENTS; PRODRUGS; RATS; SOLUBILITY; WATER;

EID: 16444369438     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.2005.00234.x     Document Type: Article

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