Liposomal lactoferrin induced significant increase of the interferon-alpha (IFN-α) producibility in healthy volunteers

BioFactors

Volumn 21, Issue 1-4, 2004, Pages 69-72

  Ishikado, Atsushi ^a   Imanaka, Hiromichi ^a   Kotani, Mayumi ^a   Fujita, Akihito ^a   Mitsuishi, Yoko ^b   Kanemitsu, Tomoyuki ^c   Tamura, Yoshiko ^c   Makino, Taketoshi ^a  

^a Sunstar Inc   (Japan)

^b Louis Pasteur Center for Medical Research   (Japan)

^c KEWPIE CORPORATION   (Japan)

Author keywords

Hepatitis C; Immunological indices; Interferon alpha producibility; Lactoferrin; Liposome; Multi lamellar vehicle; NK activity

Indexed keywords

ALPHA INTERFERON; LACTOFERRIN; LIPOSOME; PLASMA PROTEIN;

ADULT; CLINICAL EXAMINATION; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; EVALUATION; HUMAN; HUMAN EXPERIMENT; IMMUNE STATUS; IMMUNOLOGICAL MONITORING; IMMUNOLOGICAL PARAMETERS; IMMUNOMODULATION; LABORATORY TEST; MALE; NORMAL HUMAN; PRIORITY JOURNAL; VOLUNTEER; ARTICLE; BIOSYNTHESIS; BLOOD CELL COUNT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HEMATOCRIT; IMMUNOLOGY; NATURAL KILLER CELL; REFERENCE VALUE;

HEPATITIS C VIRUS;

ADULT; BLOOD CELL COUNT; BLOOD PROTEINS; DOUBLE-BLIND METHOD; HEMATOCRIT; HUMANS; INTERFERON-ALPHA; KILLER CELLS, NATURAL; LACTOFERRIN; LIPOSOMES; MALE; REFERENCE VALUES;

EID: 16444362853     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.552210113     Document Type: Conference Paper

References (4)

1. K. Uno, K. Nakano, N. Maruo et al., Determination of interferon-α- producing capacity in whole blood cultures from patients with various diseases and from healthy persons, J. Interferon Cytokine Res. 16 (1996), 911-918.
2. K. Uno and T. Kishida, Clinical utility of the measurement of IFN producing capacity, PasKen Journal 9-10 (1997), 1-6.
3. K. Tanaka, M. Ikeda, A. Nozaki et al., Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study, Jpn. J. Cancer Res. 90 (1999), 367-371.
4. J.A. Rogers and K.E. Anderson, The potential of liposomes in oral drug delivery, Crit. Rev. Ther. Drug Carrier Syst. 15 (1998), 421-480.