Comparative efficacy of oral deflazacort versus oral prednisolone in children with moderate acute asthma;Estudio comparativo de la eficacia del deflazacort frente a prednisolona en el tratamiento de la crisis asmática moderada

Anales de Pediatria

Volumn 61, Issue 3, 2004, Pages 207-212

  Gartner, S ^a   Cobos, N ^a   Perez Yarza E G ^b   Moreno, A ^a   De Frutos, C ^b   Linan S ^a   Mintegui, J ^b  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b HOSPITAL DONOSTIA   (Spain)

Author keywords

Acute asthma; Children; Deflazacort; Prednisolone; Pulmonary function

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; DEFLAZACORT; PREDNISOLONE; ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; PREGNANE DERIVATIVE;

ADOLESCENT; ARTICLE; ASTHMA; CHILD; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG TOLERABILITY; FORCED EXPIRATORY VOLUME; HOSPITALIZATION; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; OUTCOMES RESEARCH; PEAK EXPIRATORY FLOW; RANDOMIZED CONTROLLED TRIAL; SYMPTOM; TREATMENT OUTCOME; FEMALE; MALE; ORAL DRUG ADMINISTRATION; PROSPECTIVE STUDY;

ADMINISTRATION, ORAL; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; ASTHMA; CHILD; FEMALE; HUMANS; MALE; PEAK EXPIRATORY FLOW RATE; PREDNISOLONE; PREGNENEDIONES; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 16444362819     PISSN: 16954033     EISSN: None     Source Type: Journal    
DOI: 10.1157/13065276     Document Type: Article

References (34)

1. Mannino DM, Homa DM, Pertowski CA, Ashizawa A, Nixon LL, Johson CA, et al. Surveillance from asthma-United States, 1960-1995. MMWR Morb Mortal Wkly Rep CDC Surveill Summ 1998;47(SS-1)1-27.
2. Qureshi F, Zaritsky A, Poirier M. Comparative efficacy of oral dexamethasone versus oral prednisone in acute pediatric asthma. J Pediatr 2001;139:20-6.
3. Sly RM. Decreases in asthma mortality in the United States. Ann Allergy Asthma Immunol 2000;85:121-7.
4. Canny GJ, Reisman J, Healy R, Schwartz C, Petrou C, Rebuck AS, et al. Acute asthma: Observations regarding the management of a pediatric emergency room. Pediatrics 1989;83:507-12.
5. Murphy KR, Kelly HW. Advances in the management of acute asthma in children Pediatr Rev 1996;17:227-34.
6. Rachelefsky G. Treating exacerbations of asthma in children: The role of systemic corticosteroids. Pediatrics 2003;112:382-97.
7. Rowe BH, Spooner C, Ducharme FM, Bretzlaff JA, Bota GW. Early emergency department treatment of acute asthma with systemic corticosteroids. Cochrane Database Syst Rev 2000;(2):CD 002178.
8. o 97-4051).
9. British Thoracic Society Guidelines for managing asthma in adults and children. Thorax 1997;52(Suppl):1-20.
10. Canadian Asthma Guidelines. Management of patients with asthma in the emergency department and in hospital. CMAJ 1999;161:S53-S59.
11. o 02-3659).
12. Plaza V, Álvarez FJ, Casán P, Cobos N, López A, Llauger MA, et al. Guía Española para el manejo del Asma (GEMA). Arch Bronconeumol 2003;39(Supl 5):3-42.
13. Rowe BH, Spooner CH, Ducharme FM, Bretzlaff JA, Bota GW. Corticosteroids for preventing relapse following acute exacerbations of asthma (Cochrane Review). En: The Cochrane Library. Issue 3. Oxford: Update Software, 2001.
14. Markham A, Bryson HM. Deflazacort. Drugs 1995;50:317-33.
15. Chapela R. Estudio comparativo de la eficacia de dos corticoides orales en el control de la crisis grave de asma bronquial: Deflazacort y prednisona. Rev Alerg Mex 1995;42:64-8.
16. American Thoracic Society Committee on Diagnostic Standards. Definitions and classification of chronic bronchitis, asthma, and pulmonary emphysema. Am Rev Respir Dis 1962;85:762.
17. Normativas Separ: Grupo de Trabajo de la SEPAR para la práctica de la espirometría en clínica. Normativa para la práctica de la espirometría forzada. Arch Bronconeumol 1989;25:132-42.
18. Smith SR, Strunk RC. Acute asthma in the emergency department. Emerg Med 1999;46:1145-65.
19. Leffert F. The management of acute severe asthma. J Pediatr 1980;96:1-12.
20. Streetman DD, Bhatt-Metha V, Johnson CE. Management of acute, severe asthma in children. Ann Pharmacother 2002;36:1249-60.
21. Storr J, Barrell E, Barry W, Lenney W, Hatcher G. Effect of a single oral dose of prednisolone in acute childhood asthma. Lancet 1987;1:879-82.
22. Scarfone RJ, Fuchs S, Nager AL, Shane SA. Controlled trial of oral prednisone in the emergency department treatment of children with acute asthma. Pediatrics 1993;92:513-8.
23. Tang RB, Chen SJ. Soluble interleukin-2 receptor and interleukin-4 in sera of asthmatic children before and after a prednisolone course. Ann Allergy Asthma Immunol 2001;86:314-7.
24. Gibson PG, Norzila MZ, Fakes K, Simpson J, Henry RL. Pattern of airway inflammation and determinants in children with acute severe asthma. Pediatr Pulmonol 1999;28:261-70.
25. Scarfone RJ, Loiselle JM, Wiley JF, Decker JM, Henretig FM, Joffe MD. Nebulized dexamethasone versus oral prednisone in the emergency treatment of asthmatic children. Pediatrics 1995;26:480-6.
26. Schuh S, Reisman J, Alshehri M, Dupuis A, Corey M, Arseneault R, et al. A comparison of inhaled fluticasone and oral prednisone for children with severe acute asthma. N Engl J Med 2000;343:689-94.
27. Volovitz B, Bentur L, Finkelstein Y, Mansour M, Shalitin S, Nussinovitch M, et al. Effectiveness and safety of inhaled corticosteroids in controlling acute asthma attacks in children who were treated in the emergency department a controlled comparative study with oral prednisolone. J Allergy Clin Immunol 1998;102:605-9.
28. Becker JM, Arora A, Scarfone RJ, Spector ND, Fontana-Penn ME, Gracely E, et al. Oral versus intravenous corticosteroids in children hospitalized with asthma. J Allergy Clin Immunol 1999;103:586-90.
29. Gries DM, Moffitt DR, Pulos E, Carter ER. A single dosis of intramuscularly administered dexamethasone acetate is as effective as oral prednisone to treat asthma exacerbations in young children. J Pediatr 2000;136:298-303.
30. Edmonds ML, Camargo CA, Brenner BE, Rowe BH. Replacement of oral corticosteroids with inhaled corticosteroids in the treatment of acute asthma following emergency department discharge. A meta analysis. Chest 2002;121:1798-1805.
31. Hendeles L. Selecting a systemic corticosteroid for acute asthma in young children. J Pediatr 2003;142:S40-4.
32. Belker ME, Massey DM, Vaughan L. Comparative clinical efficacy of deflazacort and prednisone in the treatment of steroid-dependent asthma and asthmatic bronchitis (a multicenter study). Kansas City: Clinical Research and Statistics Department, Marion Merrel Dow Inc, 1993.
33. Avioli LV. Potency ratio-a brief synopsis. Br J Rheumatol 1993;32(Suppl 2):24-6.
34. Kayani S, Shannonn D. Adverse behavioral effects of treatment for acute exacerbation of asthma in children. Chest 2002;122:624-8.