Pressure simulation of orthodontic force in osteoblasts: A pilot study

Orthodontics and Craniofacial Research

Volumn 7, Issue 1, 2004, Pages 3-9

  Baumert, U ^a   Golan, I ^a   Becker, B ^a   Hrala, B P ^a   Redlich, M ^b   Roos, H A ^b   Reichenberg, E ^b   Palmon, A ^b   Muig, D ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Mechanical load simulation; Orthodontic tooth movement; Osteoblasts; RUNX2

Indexed keywords

RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX2; TUMOR PROTEIN;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CENTRIFUGATION; DENTAL CARE; HUMAN; METABOLISM; OSTEOBLAST; PERIODONTAL DISEASE; PHYSIOLOGY; PILOT STUDY; PRESSURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELLS, CULTURED; CENTRIFUGATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DENTAL STRESS ANALYSIS; HUMANS; NEOPLASM PROTEINS; OSTEOBLASTS; PILOT PROJECTS; PRESSURE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TOOTH MOVEMENT; TRANSCRIPTION FACTORS;

EID: 1642618243     PISSN: 16016335     EISSN: 16016343     Source Type: Journal    
DOI: 10.1046/j.1601-6335.2003.00270.x     Document Type: Article

References (32)

1. Ehrlich PJ, Lanyon LE. Mechanical strain and bone cell function: a review. Osteoporos Int 2002;13:688-700.
2. Angle EH. Treatment of Malocclusion of the Teeth. Philadelphia: White Dental Manufact; 1907.
3. Bronckers AL, Sasaguri K, Engelse MA. Transcription and immunolocalization of RUNX2 /Cbfa1/Pebp2a A in developing rodent and human craniofacial tissues: further evidence suggesting osteoclasts phagocytose osteocytes. Microsc Res Tech 2003;61:540-8.
4. Lee B, Thirunavukkarasu K, Zhou L, Pastore L, Baldini A, Hecht J et al. Missense mutations abolishing DNA binding of the osteoblast- specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nat Genet 1997;16:307-10.
5. Mundlos S, Otto F, Mundlos C, Mulliken JB, Aylsworth AS, Albright S et al. Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell 1997;89:773-9.
6. Mundlos S. Cleidocranial dysplasia: clinical and molecular genetics. J Med Genet 1999;36:177-82.
7. Golan I, Baumert U, Müβig D. Cleidocranial Dysplasia. In: National Organization for Rare Disorders, editor. NORD Guide to Rare Disorders. Philadelphia: Lippincott Williams and Wilkins; 2003. pp. 182-3.
8. Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 1997;89:755-64.
9. Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 1997;89:747-54.
10. Harada H, Tagashira S, Fujiwara M, Ogawa S, Katsumata T, Yamaguchi A et al. Cbfa1 isoforms exert functional differences in osteoblast differentiation. J Biol Chem 1999;274:6972-8.
11. Kern B, Shen J, Starbuck M, Karsenty G. Cbfa1 contributes to the osteoblast-specific expression of type I collagen genes. J Biol Chem 2001;276:7101-7.
12. Ducy P, Starbuck M, Priemel M, Shen J, Pinero G, Geoffroy V et al. A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. Genes Dev 1999;13:1025-36.
13. Drissi H, Luc Q, Shakoori R, Chuva De Sousa LS, Choi JY, Terry A et al. Transcriptional autoregulation of the bone related CBFA1/ RUNX2 gene. J Cell Physiol 2000;184:341-50.
14. Matsuda N, Yokoyama K, Takeshita S, Watanabe M. Role of epidermal growth factor and its receptor in mechanical stressinduced differentiation of human periodontal ligament cells in vitro. Arch Oral Biol 1998;43:987-97.
15. Stanford CM, Stevens JW, Brand RA. Cellular deformation reversibly depresses RT-PCR detectable levels of bone-related mRNA. J Biomech 1995;28:1419-27.
16. Roelofsen J, Klein-Nulend J, Burger EH. Mechanical stimulation by intermittent hydrostatic compression promotes bone-specific gene expression in vitro. J Biomech 1995;28:1493-503.
17. Carmeliet G, Bouillon R. The effect of microgravity on morphology and gene expression of osteoblasts in vitro. FASEB J 1999;13(Suppl.):S129-34.
18. Redlich M, Palmon A, Zaks B, Geremi E, Rayzman S, Shoshan S. The effect of centrifugal force on the transcription levels of collagen type I and collagenase in cultured canine gingival fibroblasts. Arch Oral Biol 1998;43:313-6.
19. Gebken J, Luders B, Notbohm H, Klein HH, Brinckmann J, Muller PK et al. Hypergravity stimulates collagen synthesis in human osteoblast-like cells: evidence for the involvement of p44/ 42 MAP-kinases (ERK 1/2). J Biochem (Tokyo) 1999;126:676-82.
20. Brown TD. Techniques for mechanical stimulation of cells in vitro: a review. J Biomech 2000;33:3-14.
21. Pavlin D, Dove SB, Zadro R, Gluhak-Heinrich J. Mechanical loading stimulates differentiation of periodontal osteoblasts in a mouse osteoinduction model: effect on type I collagen and alkaline phosphatase genes. Calcif Tissue Int 2000;67:163-72.
22. Ziros PG, Rojas Gil AP, Georgakopoulos T, Habeos I, Kletsas D, Basdra EK et al. The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells. J Biol Chem 2002;277:23934-41.
23. Ontiveros C, McCabe LR. Simulated microgravity suppresses osteoblast phenotype, RUNX2 levels and AP-1 transactivation. J Cell Biochem 2003;88:427-37.
24. Redlich M, Roos HA, Reichenberg E, Zaks B, Mussig D, Baumert U et al. Expression of tropoelastin in periodontal ligament fibroblast after simulation of orthodontic force. Arch Oral Biol 2003; in press.
25. Redlich M, Roos HA, Reichenberg E, Zaks B, Grosskop A, Bar Kana I et al. The effect of centrifugal force on mRNA levels of collagenase, collagen type-I, tissue inhibitors of metalloproteinases and b-actin in cultured human PDL fibroblasts. J Period Res 2003; in press.
26. Davidovitch Z. Tooth movement. Crit Rev Oral Biol Med 1991;2:411-50.
27. Reitan K. Biomechanical principles and reactions. In: Graber TM, Swain BF, editors. Orthodontics: Current Principles and Techniques. St Louis: C. V. Mosby; 1985. pp. 101-92.
28. Ozawa H, Imamura K, Abe E, Takahashi N, Hiraide T, Shibasaki Y et al. Effect of a continuously applied compressive pressure on mouse osteoblast-like cells (MC3T3-E1) in vitro. J Cell Physiol 1990;142:177-85.
29. Saito S, Kurabayashi H, Yamasaki K, Shibasaki Y. Effects of centrifugal force on bone resorption and osteoclast-like cell formation in vitro. In: Davidovitch Z, Norton LA, editors. Biological Mechanisms of Tooth Movement and Craniofacial Adaptation. Birmingham, Ala.: Harvard Society for the Advancement of Orthodontics; 1996. pp. 137-51.
30. Burger EH, Klein-Nulend J, Veldhuijzen JP. Mechanical stress and osteogenesis in vitro. J Bone Miner Res 1992;7(Suppl. 2):S397-401.
31. Fujita Y, Nishimura M, Taniwaki M, Abe T, Okuda T. Identification of an alternatively spliced form of the mouse AML1/ RUNX1 gene transcript AML1c and its expression in early hematopoietic development. Biochem Biophys Res Comm 2001;281:1248-55.
32. Satomura K, Krebsbach P, Bianco P, Gehron RP. Osteogenic imprinting upstream of marrow stromal cell differentiation. J Cell Biochem 2000;78:391-403.