Effect of Mg2SO4 usage on spinal cord ischemia-reperfusion injury: Electron microscopic and functional evaluation

European Surgical Research

Volumn 36, Issue 1, 2004, Pages 20-25

  Kaplan, Sadi ^a   Ulus, A Tulga ^a   Tütün, Ufuk ^a   Aksöyek, Ayşen ^a   Özgencil, Eser ^b   Saritaş, Zülfikar ^c   Apaydin, Nusret ^d   Pamuk, Kamuran ^b   Can, Zeynep ^b   Sürücü, Selçuk ^e   Katircioǧlu, S Fehmi ^a  

^a TURKIYE YUKSEK IHTISAS HOSPITAL   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

^c AFYON KOCATEPE UNIVERSITY   (Turkey)

^d ERCIYES UNIVERSITY   (Turkey)

^e HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Ischemia reperfusion injury; Magnesium sulfate; Spinal cord

Indexed keywords

MAGNESIUM SULFATE; NEUROPROTECTIVE AGENT;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA OCCLUSION; AORTA PRESSURE; ARTERY CLAMP; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; ELECTRON MICROSCOPY; FUNCTIONAL ASSESSMENT; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NONHUMAN; PARAPLEGIA; PRIORITY JOURNAL; RABBIT; RANDOMIZATION; REPERFUSION INJURY; SAMPLING; SPINAL CORD ISCHEMIA; TISSUE PRESERVATION; ANIMAL; AORTA; BLOOD PRESSURE; INTRAVENOUS DRUG ADMINISTRATION; NERVOUS SYSTEM; PATHOLOGY; PATHOPHYSIOLOGY; SPINAL CORD; ULTRASTRUCTURE;

ANIMALS; AORTA; BLOOD PRESSURE; INJECTIONS, INTRAVENOUS; MAGNESIUM SULFATE; MICROSCOPY, ELECTRON; NERVOUS SYSTEM; NEUROPROTECTIVE AGENTS; PARAPLEGIA; RABBITS; REPERFUSION INJURY; SPINAL CORD; SPINAL CORD ISCHEMIA;

EID: 1642578185     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000075070     Document Type: Article

References (45)

1. Connors JP, Ferguson TB, Roper CL, Weldon CS: The use of the TDMAC-heparin shunt in replacement of the descending thoracic aorta. Ann Surg 1975;181:735.
2. Svensson LG, Crawford ES, Hess KR, Coselli JS, Safi HJ: Experience with 1,509 patients undergoing thoracoabdominal aortic operations. J Vasc Surg 1993;17:357.
3. Woods KL: Possible pharmacological actions of magnesium in acute myocardial infarction. Br J Clin Pharmacol 1991;32;3-10.
4. Granger DN: Role of xanthine oxidase and granulocytes in ischemia and reperfusion injury. Am J Physiol 1988;24:H1269-H1275.
5. McGarrity ST, Stephenson AH, Webster RO: Regulations of human neutrophil function by adenine nucleotides. J Immunol 1989;142:1986-1994.
6. White RE, Hartzell HC: Magnesium ions in cardiac function. Biochem Pharmacol 1989;38:859-864.
7. Reinhart RA: Clinical correlates of the molecular and cellular actions of magnesium on the cardiovascular system. Am Heart J 1991;121:1513-1521.
8. Shechter M, Sharir M, Labrador MJP, Forrester J, Silver B, Merz NB: Oral magnesium therapy improves endothelial function in patients with coronary artery disease. Circulation 2000;102:2353-2358.
9. Mihara M, Uchiyama M: Determination of malondialdehyde precursors in tissues by thiobarbituric acid test. Anal Biochem 1978;86:271-278.
10. Thomas C, Larry H, Samuel R, Edward C, Basil S: Protecting the ischemic spinal cord during aortic clamping. The influence of anesthetics and hypothermia. Ann Surg 1992;215-5:409-416.
11. Crawford ES, Svensson LG, Hess KR: A prospective randomized study of CSF drainage to prevent paraplegia after high-risk surgery on the thoracoabdominal aorta. J Vasc Surg 1990;13:36.
12. Schittek A, Bennink GB, Cooley DA, Langford LA: Spinal cord protection with intravenous nimodipine. A functional and morphologic evaluation J Thorac Cardiovasc Surg 1992;104:1100.
13. 1 and superoxide dismutase prevent ischemic spinal cord injury after thoracic aortic cross-clamping? Eur Vasc Surg 1990;4:19.
14. Fowl RJ, Patterson RB, Gewirtz RJ, Anderson DK: Protection against postischemic spinal cord injury using a new 21-aminosteroid. J Surg Res 1990;48:597.
15. Agee JM, Flanagan T, Blackbourne LH, Kron IL, Tribble CG: Reducing postischemic paraplegia using conjugated superoxide dismutase. Ann Thorac Surg 1982;33:64.
16. Svenson LG, Stewart RW, Cosgrove DM: Intrathecal papaverine for the prevention of paraplegia after operation on the thoracic or abdominal aorta. J Thorac Cardiovasc Surg 1988;96:823.
17. Ulus AT, Tütün U, Sürücü S, Apaydin N, Gökçe P, Katircioǧlu SF: Functional outcome in model of spinal cord ischemia: use of enoximone. Asian Cardiovasc Thorac Ann 2000;8:216-220.
18. Katircioǧlu SF, Ulus AT, Gökçe P, Sürü cü S: Iloprost protects the spinal cord during aortic cross-clamping in a canine model. J Cardiovasc Surg 2000;41:89-93.
19. Katircioǧlu SF, Saritaş Z, Yücel Y, Bayazit M, Taşdemir T, Bayazit K: Spinal cord protection with the use of prostacyclin during aortic occlusion. J Surg Res 1996;65:77-81.
20. Headrick JP, McKirdy JC, Willis RJ: Functional and metabolic effects of extracellular magnesium in normoxic and ischemic myocardium. Am J Physiol 1998;275:H917-H929.
21. Rassmusen HS, Norregard P, Lindeneg O, McNair P, Backer V, Balslev S: Intravenous magnesium in acute myocardial infarction. Lancet 1986;i:234-236.
22. Pearson PJ, Evora PR, Seccombe JF, Schaff HV: Hypomagnesemia inhibits nitric oxide release from coronary endothelium: Protective role of magnesium infusion after cardiac operations. Ann Thorac Surg 1998;65:967-972.
23. Dickens BF, Weglicki WB, Li YS, Mak IT: Magnesium deficiency in vitro enhances free radical-induced intracellular oxidation and cytotoxicity in endothelial cells. FEBS Lett 1992;311:187-191.
24. 2 pretreatment. Am J Physiol 1998;254:H702-H708.
25. Schittek A, Bennink GB, Cooley DA, Langford LA: Magnesium deficiency potentiates free radical production associated with myocardial infarction. J Assoc Physicians India 2000;48:484-485.
26. Chaudry IH, Clemens MG, Baue AE: The role of ATP-magnesium in ischemia and shock. Magnesium 1986;5:211-220.
27. Chaudry IH, Stephan RN, Dean RE, Clemens MG: The use of ATP-magnesium following liver ischemia. Magnesium 1988;7:68-77.
28. Simpson JI, Eide TR, Schiff GA, Clagnaz JF et al: Intrathecal magnesium sulfate protects the spinal cord from ischemic injury during thoracic aortic cross-clamping. Anesthesiology 1994;81:1493-1499.
29. Suzer T, Coskun E, Islekel H, Tahta K: Neuroprotective effect of magnesium on lipid peroxidation and axonal function after experimental spinal cord injury. Spinal Cord 1999;37:480-484.
30. 2+ after impact trauma in rats. Adv Neurol 1990;52:225-232.
31. Lemke M, Faden AI: Edema development and ion changes in rat spinal cord after impact trauma: Injury dose-response studies. J Neurotrauma 1990;7:41-54.
32. 31P-MRS. Brain Res 1989;490:144-147.
33. Robertson CS, Foltz R, Grossman RG, Goodman JC: Protection against experimental ischemic spinal cord injury. J Neurosurg 1986;64:633-642.
34. Lang-Lazdunski L, Heurteaux C, Dupont H, Widmann C, Lazdunski M: Prevention of ischemic spinal cord injury: Comparative effect of magnesium sulfate and riluzole. J Vasc Surg 2000;32:179-189.
35. Rokkas CK, Cronin CS, Lobner DC, Choi DW, Kouchoukos NT: Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia. Ann Thorac Surg 1994;58:312-320.
36. Lipton SA, Rosenberg PA: Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med 1994;330:613-622.
37. Regan RF, Jasper E, Guo Y, Scott Panter S: The effect of magnesium on oxidative neuronal injury in vitro. J Neurochem 1998;70:77-85.
38. Thurnau GR, Kemp DB, Jarvis A: Cerebrospinal fluid levels of magnesium in patients with preeclampsia after treatment with intravenous magnesium sulfate: A preliminary report. Am J Obstet Gynecol 1987;157:1435-1438.
39. Muir KW, Lees KR: A randomized, double-blind, placebo-controlled pilot trial of intravenous magnesium sulfate in acute stroke. Stroke 1995;26:1183-1188.
40. 2+ protect against irreversible damage during CNS ischemia. Stroke 1984;15:695-698.
41. Lang-Lazdunski L, Bachet J: Pharmacological spinal cord protection with magnesium during replacement of the thoracic and thoracoab-dominal aorta. Ann Thorac Surg 2001;72:2180-2181.
42. Nadler JL, Goodson S, Rude RK: Evidence that prostacyclin mediates the vascular action of magnesium in humans. Hypertension 1987;9:379-383.
43. Reinhart RA: Clinical correlates of the molecular and cellular actions of magnesium on the cardiovascular system. Am Heart J 1991;121:1513-1521.
44. 2 utilization for spinal cord protection during experimental thoracic aortic occlusion. J Cardiovasc Surg 1999;40:495-499.
45. Katircioglu SF, Saritaş Z, Ulus AT, Yamak B, Yücel D, Ayaz S: Iloprost added to the cardioplegic solutions improves myocardial performance. Prostaglandins 1998;55:51-65.