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Volumn 14, Issue 3, 2004, Pages 801-804

Synthesis of oligonucleotide 2′-conjugates via amide bond formation in solution

Author keywords

Conjugate; Oligonucleotide; Peptide

Indexed keywords

ALDEHYDE DERIVATIVE; AMIDE; AMINO ACID DERIVATIVE; CARBOXYL GROUP; CYANAMIDE; METHYL GROUP; OLIGONUCLEOTIDE; PEPTIDE DERIVATIVE; PERIODATE; SODIUM CHLORITE;

EID: 1642575089     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.10.069     Document Type: Article
Times cited : (19)

References (20)
  • 17
    • 85030904659 scopus 로고    scopus 로고
    • note
    • 18 column (3.9×300 mm), dual wavelength detection (215 and 254 nm); buffer A: 5% of MeCN (v/v) in 0.1 M triethylammonium acetate, buffer B: MeCN; flow rate 1 mL/min, gradient of B in A: 0-5%, 5 min, 5-15%, 10 min, 15-40, 30 min, 40-80%.
  • 18
    • 85030912788 scopus 로고    scopus 로고
    • note
    • 11.
  • 19
    • 85030910890 scopus 로고    scopus 로고
    • note
    • 4 solution (0.2 mL) followed by acetone (1.5 mL) and analyzed using reversed-phase or ion-pair HPLC and MALDI-TOF mass spectroscopy. Oligonucleotide II was used to optimize the conjugation conditions (data not shown).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.