Discorhabdins I and L, Cytotoxic Alkaloids from the Sponge Latrunculia brevis

Journal of Natural Products

Volumn 67, Issue 3, 2004, Pages 463-465

  Reyes, Fernando ^a   Martín, Rocío ^a   Rueda, Ana ^a   Fernández, Rogelio ^a   Montalvo, David ^a   Gómez, Cristina ^a   Sánchez Puelles, José Ma ^a  

^a PHARMAMAR S A   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; CYTOTOXIC AGENT; DISCORHABDIN B; DISCORHABDIN I; DISCORHABDIN L; DISCORHABDIN R; NATURAL PRODUCT; PRIANOSIN D; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CYTOTOXICITY; DRUG CYTOTOXICITY; DRUG STRUCTURE; LATRUNCULIA BREVIS; MARINE ENVIRONMENT; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SPONGE (PORIFERA); TUMOR CELL LINE;

ALKALOIDS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OCEANS AND SEAS; PORIFERA; QUINONES;

INVERTEBRATA; LATRUNCULIA; PORIFERA;

EID: 1642546945     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np0303761     Document Type: Article

References (13)

1. Blunt, J. W.; Copp, B. R.; Munro, M. H. G.; Northcote, P. T.; Prinsep, M. R. Nat. Prod. Rep. 2003, 20, 1-48, and previous papers in this series.
2. Ford, J.; Capon, R. J. J. Nat. Prod. 2000, 63, 1527-1528, and references therein.
3. Perry, N. B.; Blunt, J. W.; McCombs, J. D.; Munro, M. H. G. J. Org. Chem. 1986, 51, 5476-5478.
4. Perry, N. B.; Blunt, J. W.; Munro, M. H. G.; Higa, T.; Sakai, R. J. Org. Chem. 1988, 53, 4127-4128.
5. Perry, N. B.; Blunt, J. W.; Munro, M. H. G. Tetrahedron 1988, 44, 1727-1734.
6. Copp, B. R.; Fulton, K. F.; Perry, N. B.; Blunt, J. W.; Munro, M. H. G. J. Org. Chem. 1994, 59, 8233-8238.
7. Blunt, J. W.; Munro, M. H. G.; Batterhill, C. N.; Copp, B. R.; McCombs, J. D.; Perry, N. B.; Prinsep, M.; Thompson, A. M. New J. Chem. 1990, 14, 761-781.
8. Perry, N. B.; McCombs, J. D.; Copp, B. R.; Rea, J.; Lill, R.; Major, D.; Andrew, C.; Fulton, K.; Linton, M.; Bringans, S.; Blunt, J.; Munro, M. The 37th Annual Meeting of the American Society of Pharmacognosy, University of California, Santa Cruz, CA, July 27-31, 1996; p 28.
9. Kobayashi, J.; Cheng, J.; Ishibashi, M.; Nakamura, H.; Ohizumi, Y.; Hirata, Y.; Sasaki, T.; Lu, H.; Clardy, J. Tetrahedron Lett. 1987, 28, 4939-4942.
10. Yang, A.; Baker, B. J.; Grimwade, J.; Leonard, A.; McClintock, J. B. J. Nat. Prod. 1995, 58, 1596-1599.
11. Gunasekera, S. P.; McCarthy, P. J.; Longley, R. E.; Pomponi, S. A.; Wright, A. E.; Lobkovsky, E.; Clardy, J. J. Nat. Prod. 1999, 62, 173-175.
12. Dijoux, M. G.; Gamble, W. R.; Hallock, Y. F.; Cardellina, J. H., II; van Soest, R.; Boyd, M. R. J. Nat. Prod. 1999, 62, 636-637.
13. Skehan, P.; Storeng, R.; Scudiero, D.; Monks, A.; McMahon, J.; Vistica, D.; Warren, J. T.; Bokesch, H.; Kenney, S.; Boyd, M. R. J. Natl. Cancer Inst. 1990, 82, 1107-1112.