The effect of leucocyte-depleting arterial line filters on cerebral microemboli and neuropsychological outcome following coronary artery bypass surgery

European Journal of Cardio-thoracic Surgery

Volumn 25, Issue 2, 2004, Pages 267-274

  Whitaker, Donald C ^a   Newman, Stanton P ^a   Stygall, Jan ^a   Hope Wynne, Chris ^a   Harrison, Michael J G ^a   Walesby, Robin K ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Coronary artery bypass graft surgery; Filters; Leucocyte; Microemboli; Neuropsychology

Indexed keywords

ADULT; AGED; BLOOD FILTER; BRAIN DISEASE; BRAIN EMBOLISM; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; DOPPLER ECHOGRAPHY; FEMALE; HUMAN; MALE; MICROEMBOLISM; MIDDLE CEREBRAL ARTERY; NEUROPROTECTION; NEUROPSYCHOLOGICAL TEST; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

AGED; BLOOD FLOW VELOCITY; COGNITION DISORDERS; CORONARY ARTERY BYPASS; FEMALE; FILTRATION; HUMANS; INTRACRANIAL EMBOLISM AND THROMBOSIS; INTRAOPERATIVE CARE; LEUKAPHERESIS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; MIDDLE CEREBRAL ARTERY; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES;

EID: 1642534505     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2003.11.007     Document Type: Conference Paper

References (24)

1. Newman S.P., Stygall J. Neuropsychological outcome following cardiac surgery. Newman S.P., Harrison M.J.G. The brain and cardiac surgery. 2nd ed :2000;21-49 Harwood Academic Press, London.
2. Pugsley W., Klinger L., Paschalis C., Treasure T., Harrison M., Newman S.P. The impact of microemboli during cardiopulmonary bypass on neuropsychological functioning. Stroke. 25:1994;1393-1399.
3. Clark R.E., Brillman J., Davis D.A. Microemboli during coronary artery bypass grafting. J Thorac Cardiovasc Surg. 109:1995;249-258.
4. Neville M.J., Butterworth J., James R.L., Hammon J.W., Stump D.A. Similar neurobehavioural outcome after valve or coronary artery operations despite differing embolic counts. J Thorac Cardiovasc Surg. 109:2001;249-258.
5. Allen S. The role of leucocytes in the systemic inflammatory response and the potential impact of leucocyte depletion. Cardiovasc Engng. 2:1997;34-54.
6. Johnson D., Thomson D., Mycyk T., Burbridge B., Mayers I. Depletion of neutrophils by filter during aortocoronary bypass surgery transiently improves cardiorespiratory status. Chest. 107:1995;1253-1259.
7. Hachida M., Hanayama N., Okamura T., Akasawa T., Maeda T., Bonkohara Y., Endo M., Hashimoto A., Koyanagi H. Role of leucocyte depletion in reducing injury to myocardium and lung during cardiopulmonary bypass. Am Soc Artif Intern Organs J. 41:1995;M291-M294.
8. Ringlestein E.B., Droste D.W., Babikan V.L., Evans D.H., Grosset D.G., Kaps M., Markus H.S., Russell D., Siebler M. Consensus on microemboli detection by TCD. International Consensus Group on Microembolus Detection. Stroke. 29:1998;725-729.
9. Kong R.S., Butterworth J., Aveling W., Stump D., Harrison M.J.G., Hammon J., Stygall J., Rorie K.D., Newman S.P. Clinical trial of the neuroprotectant clomethiazole in coronary artery bypass graft surgery. A randomized controlled trial. Anesthesiology. 97:2002;585-591.
10. Radloff L. The CES-D scale. A self-report depression scale for research in the general population. Appl Psychosoc Meas. 1:1977;385-401.
11. Speilberger C.D., Gorusch R.L. Manual for the State-Trait Anxiety Inventory. 1983;Consulting Psychologists Press, Palo Alto, CA.
12. Bowles B.J., Lee J.D., Dang C.R., Taoka S.N., Johnson E.W., Lau E.M., Nekomoto K. Coronary artery bypass performed without the use of cardiopulmonary bypass is associated with reduced cerebral microemboli and improved clinical results. Chest. 119:2001;25-30.
13. Royse A.G., Royse C.F., Ajani A.E., Symes E., Maruff P., Karagiannis S., Gerraty R.P., Grigg L.E., Davis S. Reduced neuropsychological dysfunction using epiaortic scanning and the exclusive Y graft. Ann Thorac Surg. 69:2000;1431-1438.
14. Moser D.J., Ferneyhough K.C., Bauer R.M., Arndt S., Schultz S.K., Haynes W.G., Staples E.D., Alexander J., Davies L.K., O'Brien D.J. Unilateral vs. bilateral ultrasound in the monitoring of cerebral microemboli. Ultrasound Med Biol. 27:2001;757-760.
15. Wijman C.A., Babikian V.L., Winter M.R., Pochay V.E. Distribution of cerebral microembolism in the anterior and middle cerebral arteries. Acta Neurol Scand. 101:2000;122-127.
16. Brooker R.F., Brown W.R., Moody D.M., Hammon J.W., Reboussin D.M., Deal D.D., Ghazi-Birry H.S., Stump D.A. Cardiotomy suction: a major source of brain lipid emboli during cardiopulmonary bypass. Ann Thorac Surg. 65:1998;1652-1655.
17. Kincaid E.H., Jones T.J., Stump D.A., Brown W.R., Moody D.M., Deal D.D., Hammon J.W. Processing scavenged blood with a cell saver reduces cerebral lipid microembolisation. Ann Thorac Surg. 70:2000;1296-1300.
18. Musumeci F., Feccia M., MacCarthy P.A., Ellis G.R., Mammana L., Brinn F., Penny W.J. Prospective randomized trial of single clamp technique versus intermittent ischaemic arrest: myocardial and neurological outcome. Eur J Cardiothorac Surg. 13:1998;702-709.
19. Padayachee T.S., Parsons S., Theobold R., Linley J., Gosling R.G., Deverall P.B. The detection of microemboli in the middle cerebral artery during cardiopulmonary bypass: a transcranial Doppler ultrasound investigation using membrane and bubble oxygenators. Ann Thorac Surg. 44:1987;298-302.
20. Plochl W., Cook D.J. Quantification and distribution of cerebral emboli during cardiopulmonary bypass in swine. Anesthesiology. 90:1999;183-190.
21. Clark R.E., Brillman J., Davis D.A. Microemboli during coronary artery bypass grafting. J Thorac Cardiovasc Surg. 109:1995;249-258.
22. Barbut D., Lo Y.-W., Gold J.P., Trifiletti R.R., Yao F.S.F., Hager D.N., Hinton R.B., Isom O.W. Impact of embolization during coronary artery bypass grafting on outcome and length of stay. Ann Thorac Surg. 63:1997;998-1002.
23. Fearn S.J., Pole R., Wesnes K., Faragher E.B., Hooper T.L., McCollum C.N. Cerebral injury during cardiopulmonary bypass: emboli impair memory. J Thorac Cardiovasc Surg. 121:2001;1150-1160.
24. Neville M.J., Butterworth J., James R.L., Hammon J.W., Stump D.A. Similar neurobehavioural outcome after valve or coronary artery operations despite differing embolic counts. J Thorac Cardiovasc Surg. 109:2001;249-258.