The Antiinflammatory Effects of Ketamine in Endotoxemic Rats during Moderate and Mild Hypothermia

Anesthesia and Analgesia

Volumn 98, Issue 4, 2004, Pages 1114-1120

  Taniguchi, Takumi ^a   Kanakura, Hiroko ^a   Takemoto, Yasuhiro ^a   Yamamoto, Ken ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; ESCHERICHIA COLI ENDOTOXIN; INTERLEUKIN 6; KETAMINE; PENTOBARBITAL; TUMOR NECROSIS FACTOR ALPHA;

ACID BASE BALANCE; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CRITICAL ILLNESS; DRUG EFFECT; ENDOTOXEMIA; HEMODYNAMICS; HYPOTENSION; HYPOTHERMIA; MALE; METABOLIC ACIDOSIS; NONHUMAN; PRIORITY JOURNAL; RAT; RECTUM TEMPERATURE; SYSTOLIC BLOOD PRESSURE;

EID: 1642502510     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000100740.07331.A2     Document Type: Article

References (19)

1. Wakabayashi G, Gelfard JA, Jung WK, et al. Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock like state and tissue injury in rabbits without endotoxemia; comparison to Escherichia coli. J Clin Invest 1991;87:1925-35.
2. Casey LC, Balk RA, Bone RC. Plasma cytokines and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med 1993;119:771-8.
3. Marty C, Misset B, Tamion F, et al. Circulating interleukin-8 concentrations in patients with multiple organ failure of septic and nonseptic origin. Crit Care Med 1994;22:673-9.
4. Kuhns DB, Alvord WG, Gallin JI. Increased circulating cytokines, cytokine antagonists, and E-selectin after intravenous administration of endotoxin in human. J Infect Dis 1995;171:145-52.
5. Damas P, Reuter A, Gysen P, et al. Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans. Crit Care Med 1989;17:975-8.
6. Natanson C, Eichenholz PW, Danner RL, et al. Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock. J Exp Med 1989;169:823-32.
7. Larsen B, Hoff G, Wilhelm W, et al. Effect of intravenous anesthetics on spontaneous and endotoxin-stimulated cytokine response in cultured human whole blood. Anesthesiology 1998;89:1218-27.
8. Takenaka I, Ogata M, Koga K, at al. Ketamine suppresses endotoxin-induced tumor necrosis factor alpha production in mice. Anesthesiology 1994;80:402-8.
9. Taniguchi T, Yamamoto K, Ohmoto N, et al. Effects of propofol on hemodynamic and inflammatory responses to endotoxemia in rats. Crit Care Med 2000;28:1101-6.
10. Taniguchi T, Shibata K, Yamamoto K. Ketamine inhibits endotoxin-induced shock in rats. Anesthesiology 2001;95:928-32.
11. Marion DW, Penrod LE, Kelsey SF, et al. Treatment of traumatic brain injury with moderate hypothermia. N Engl J Med 1997;336:540-6.
12. Bernard SA, Gray TW, Buist MD, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002;356:557-63.
13. The Hypothermia After Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002;346:549-56.
14. Kawasaki T, Ogata M, Kawasaki C, et al. Ketamine suppresses proinflammatory cytokine production in human whole blood in vitro. Anesth Analg 1999;89:665-9.
15. Naslund TC, Hollier LH, Money SR, et al. Protecting the ischemic spinal cord during aortic clamping. Ann Surg 1992;215:409-15.
16. Yli-Hankala A, Edmonds HL Jr, Jiang YD, et al. Outcome effects of different protective hypothermia levels during cardiac arrest in rats. Acta Anaeth Scand 1997;41:511-5.
17. Marik PE, Zaloga GP. Hypothermia and cytokines in septic shock. Intensive Care Med 2000;26:716-21.
18. Taniguchi T, Takemoto Y, Kanakura H, et al. Dose-related effects of ketamine on mortality and cytokine responses to endotoxin-induced shock in rats. Anesth Analg 2003;97:1769-72.
19. Leslie K, Sessler DI, Bjorksten AR, et al. Mild hypothermia alters propofol pharmacokinetics and increases the duration of action of atracurium. Anesth Analg 1995;80:1007-14.