Total hepatectomy model in pigs: Revised method for vascular reconstruction using a rigid vascular prosthesis

European Surgical Research

Volumn 36, Issue 1, 2004, Pages 8-12

  Sosef, M N ^a   Van Gulik, T M ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Animal model; Bioartificial liver; Hepatectomy; Hepatic failure; Pigs

Indexed keywords

AMMONIA; HEMOGLOBIN; POLYETHYLENE;

AMMONIA BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL LIVER; BIOARTIFICIAL ORGAN; BLOOD VESSEL PROSTHESIS; CARDIOGENIC SHOCK; CAUSE OF DEATH; CAVA VEIN; CONTROLLED STUDY; DEVICE; FEMALE; HEART ARRHYTHMIA; HEMOGLOBIN DETERMINATION; LIVER FAILURE; LIVER RESECTION; NONHUMAN; PORTAL VEIN; PORTOCAVAL SHUNT; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RELIABILITY; REPRODUCIBILITY; RIGIDITY; SURGICAL TECHNIQUE; SURVIVAL RATE; SURVIVAL TIME; SWINE; VASCULAR SURGERY; VEIN RECONSTRUCTION;

AMMONIA; ANIMALS; ARRHYTHMIA; BLOOD VESSEL PROSTHESIS; DISEASE MODELS, ANIMAL; EQUIPMENT DESIGN; FEMALE; HEMOGLOBINS; HEPATECTOMY; LIVER FAILURE, ACUTE; LIVER, ARTIFICIAL; POLYETHYLENE; POSTOPERATIVE PERIOD; REPRODUCIBILITY OF RESULTS; SHOCK; SURVIVAL ANALYSIS; SWINE;

EID: 1642496853     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000075068     Document Type: Article

References (12)

1. Mazziotti A, Bernardi M, Antonini L, Dioguardi FS, Bellusci R, Papa V, Tacconi C, Gasbarrini G, Cavallari A, Possati L: Plasma amino acid patterns in experimental acute hepatic failure: Comparison between hepatectomy and liver devascularization in pigs. Surgery 1981;90:527-534.
2. Filipponi F, Boggi U, Meacci L, Burchielli S, Vistoli F, Bellini R, Prota C, Colizzi L, Kusmic C, Campani D, Gneri C, Trivella MG, Mosca F: A new technique for total hepatectomy in the pig for testing liver support devices. Surgery 1999;125:448-455.
3. Firor WM, Stinson E: Total extirpation of the dog's liver in one stage. Bull J Hopkins Hosp 1929;44:138-148.
4. Sosef MN, Abrahamse LS, van De Kerkhove MP, Hartman R, Chamuleau RA, van Gulik TM: Assessment of the AMC-bioartificial liver in the anhepatic pig. Transplantation 2002;73:204-209.
5. Newsome PN, Plevris JN, Nelson LJ, Hayes PC: Animal models of fulminant hepatic failure: A critical evaluation. Liver Transpl 2000;6:21-31.
6. Flendrig LM, Calise F, Di Florio E, Mancini A, Ceriello A, Santaniello W, Mezza E, Sicoli F, Belleza G, Bracco A, Cozzolino S, Scala D, Mazzone M, Fattore M, Gonzales E, Chamuleau RA: Significantly improved survival time in pigs with complete liver ischemia treated with a novel bioartificial liver. Int J Artif Organs 1999;22:701-709.
7. Mann FC, Magath TB: The effect of total removal of the liver. Trans Sect Pathol Physiol Am Med Assoc 1921, pp 419-511.
8. Olafsson S, Gottstein J, Blei AT: Brain edema and intracranial hypertension in rats after total hepatectomy. Gastroenterology 1995;108:1097-1103.
9. Engelbrecht GH, Hickman R, Kahn D: One-stage total hepatectomy in the rat using microvascular anastomoses. Microsurgery 1999;19:95-97.
10. Tonnesen K, Balling H: Cerebral flow and metabolism in experimental liver failure. A comparison between hepatectomy and total hepatic devascularization in pigs. Acta Chir Scand 1986;152:439-445.
11. Vistoli F, Boggi U, Bellini R, Colizzi L, Kusmic C, Burchielli S, Campani D, Gneri C, Trivella MG, Filipponi F, Mosca F: A standardized pig model of total hepatectomy for testing liver support systems. Transplant Proc 2000;32:2723-2725.
12. Terblanche J, Hickman R: Animal models of fulminant hepatic failure. Dig Dis Sci 1991;36:770-774.