Whole blood assay to access T cell-immune responses to Mycobacterium tuberculosis antigens in healthy brazilian individuals

Memorias do Instituto Oswaldo Cruz

Volumn 99, Issue 1, 2004, Pages 53-55

  Antas, Paulo R Z ^a   Cardoso, Fernando L L ^a   Oliveira, Eliane B ^a   Gomes, Patrícia K C ^a   Cunha, Kátia S ^b   Sarno, Euzenir N ^a   Sampaio, Elizabeth P ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b Hospital Raphael de Paula Souza   (Brazil)

Author keywords

Interferon ; Latent TB infection; PPD; T cell responses; Tuberculosis (TB); Whole blood

Indexed keywords

GAMMA INTERFERON; MYCOBACTERIUM ANTIGEN;

ADULT; ARTICLE; BLOOD ANALYSIS; BRAZIL; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDEMIC DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL CULTURE; HUMAN EXPERIMENT; IMMUNOREACTIVITY; IN VITRO STUDY; MALE; MONONUCLEAR CELL; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NORMAL HUMAN; PROTEIN DETERMINATION; SUPERNATANT; VOLUNTEER;

MYCOBACTERIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 1642485832     PISSN: 00740276     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0074-02762004000100009     Document Type: Article

References (10)

1. Antas PRZ, Oliveira EB, Milagres AS, Franken KC, Ottenhoff THM, Klatser P, Sarno EN, Sampaio EP 2002. Kinetics of T Cell-activation molecules in response to Mycobacterium tuberculosis antigens. Mem Inst Oswaldo Cruz 97: 1097-1099.
2. Bocchieri MH, Talle MA, Maltese LM, Ragucci IR, Hwang CC, Goldstein G 1995. Whole blood culture for measuring mitogen induced T cell proliferation provides superior correlations with disease state and T cell phenotype in asymptomatic HIV-infected subjects. J Immunol Methods 181: 233-243.
3. Brock I, Munk ME, Kok-Jensen A, Andersen P 2001. Performance of whole blood IFN-gamma test for tuberculosis diagnosis based on PPD or the specific antigens ESAT-6 and CFP-10. Int J Tuberc Lung Dis 5: 462-467.
4. Cardoso FLL, Antas PRZ, Milagres AS, Geluk A, Franken KLC, Oliveira EB, Teixeira HC, Nogueira SA, Sarno EN, Klatser P, Ottenhoff THM, Sampaio EP 2002. T cell responses to the Mycobacterium tuberculosis specific antigen ESAT-6 in Brazilian tuberculosis patients. Infect Immun 70: 6707-6714.
5. De Luca PM, Mayrink W, Santiago MA, Nogueira R, Conceição- Silva F, Melo G, Mendonça SCF 2003. Randomised, double-blind, placebo-controlled study on the immunogenicity of the leishmanin skin test. Trans R Soc Trop Med Hyg 97 (in press).
6. Franken KL, Hiemstra HS, van Meijgaarden KE, Subronto Y, den Hartigh J, Ottenhoff TH, Drijfhout JW 2000. Purification of his-tagged proteins by immobilized chelate affinity chromatography: the benefits from the use of organic solvent. Protein Expr Purif 18: 95-99.
7. Geluk A, van Meijgaarden KE, Franken KL, Subronto YW, Wieles B, Arend SM, Sampaio EP, de Boer T, Faber WR, Naafs B, Ottenhoff TH 2002. Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis. Infect Immun 70: 2544-2548.
8. Kochi A 1991. The global tuberculosis situation and the new control strategy of the World Health Organization. Tubercle 72: 71.
9. Mazurek GH, LoBue PA, Daley CL, Bernardo J, Lardizabal AA, Bishai WR, Iademarco MF, Rothel JS 2001. Comparison of a whole-blood interferon gamma assay with tuberculin skin testing for detecting latent Mycobacterium tuberculosis infection. JAMA 286: 1740-1747.
10. Stenger S, Modlin RL 1999. T cell mediated immunity to Mycobacterium tuberculosis. Curr Opin Microbiol 2: 89-93.