Mechanisms of bone resorption in myeloma

Journal of Musculoskeletal Neuronal Interactions

Volumn 3, Issue 4, 2003, Pages 271-272

  Roodman, G David ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

IL 3; MIP 1 ; Myeloma; Osteoclasts

Indexed keywords

MACROPHAGE INFLAMMATORY PROTEIN 1; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; TRANSCRIPTION FACTOR RUNX1;

ARTICLE; BONE DESTRUCTION; BONE PAIN; BONE REMODELING; CELL DIFFERENTIATION; DISEASE ACTIVITY; HUMAN; HYPERCALCEMIA; MOLECULAR CLONING; MYELOMA; OSTEOCLAST; OSTEOLYSIS; PATHOLOGIC FRACTURE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TRANSCRIPTION REGULATION;

EID: 1642473016     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Callander NS, Roodman GD. Myeloma bone disease. Review. Semin Hematol 2001; 38:276-285.
2. Sezer O, Heider U, Zavrski I, Kuhne CA, Hofbauer LC. RANK ligand and osteoprotegerin in myeloma bone disease. Blood 2003; 101:2094-2098. Epub 2002 Nov 07. Review.
3. Sezer O, Heider U, Jakob C, Eucker J, Possinger K. Human bone marrow myeloma cells express RANKL. J Clin Oncol 2002; 20:353-354.
4. Sezer O, Heider U, Jakob C, Zavrski I, Eucker J, Possinger K, Sers C, Krenn V. Immunocytochemistry reveals RANKL expression of myeloma cells. Blood 2002; 99:4646-4647.
5. Standal T, Seidel C, Hjertner O, Plesner T, Sanderson RD, Waage A, Borset M, Sundan A Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells. Blood 2002; 100:3002-3007.
6. Choi SJ, Cruz JC, Craig F, Chung H, Devlin RD, Roodman GD, Alsina M. Macrophage inflammatory protein 1α is a potential osteoclast stimulatory factor in multiple myeloma. Blood 2000; 96:671-675.
7. Han JH, Choi SJ, Kurihara N, Koide M, Oba Y, Roodman GD. Macrophage inflammatory protein-1α is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand. Blood 2001; 97:3349-3353.
8. Choi SJ, Oba Y, Gazitt Y, Alsina M, Cruz J, Anderson J, Roodman GD. Antisense inhibition of macrophage inflammatory protein 1α. blocks bone destruction in a model of myeloma bone disease. J Clin Invest 2001; 108:1833-1841.
9. Oyajobi BO, Franchin G, Williams PJ, Pulkrabek D, Gupta A, Munoz S, Grubbs B, Zhao M, Chen D, Sherry B, Mundy GR. Dual effects of macrophage inflammatory protein-1α on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease. Blood 2003; 102:311-319.
10. Choi SJ, Oba T, Callander NS, Jelinek DF, Roodman GD. AML-1A and AML-1B regulation of MIP-1α expression in multiple myeloma. Blood 2003; 101:3778-3783.
11. Lee JW, Chung HY, Jelinek DF, Callander NS, Roodman GD, Choi SJ. IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells. Blood 2003 (submitted).