-
1
-
-
0032606088
-
Model building by comparison at CASP3: Using expert knowledge and computer automation
-
Bates, P. A., and M. J. Sternberg. 1999. Model building by comparison at CASP3: using expert knowledge and computer automation. Proteins Suppl. 3:47-54.
-
(1999)
Proteins Suppl.
, vol.3
, pp. 47-54
-
-
Bates, P.A.1
Sternberg, M.J.2
-
2
-
-
0342424187
-
Fast prediction and visualization of protein binding pockets with PASS
-
Brady, G. P., Jr., and P. F. Stouten. 2000. Fast prediction and visualization of protein binding pockets with PASS. J. Compul. Aided Mol. Des. 14:383-401.
-
(2000)
J. Compul. Aided Mol. Des.
, vol.14
, pp. 383-401
-
-
Brady Jr., G.P.1
Stouten, P.F.2
-
3
-
-
0035123060
-
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
-
Chacko, B. M., B. Qin, J. J. Correia, S. S. Lam, M. P. de Caestecker, and K. Lin. 2001. The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization. Nat. Struct. Biol. 8:248-253.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 248-253
-
-
Chacko, B.M.1
Qin, B.2
Correia, J.J.3
Lam, S.S.4
De Caestecker, M.P.5
Lin, K.6
-
4
-
-
0029802485
-
A transcriptional partner for MAD proteins in TGF-β signalling
-
Chen, X., M. J. Rubock, and M. Whitman. 1996. A transcriptional partner for MAD proteins in TGF-β signalling. Nature 383:691-696.
-
(1996)
Nature
, vol.383
, pp. 691-696
-
-
Chen, X.1
Rubock, M.J.2
Whitman, M.3
-
5
-
-
0030961168
-
Smad4 and FAST-1 in the assembly of activin-responsive factor
-
Chen, X., E. Weisberg, V. Fridmacher, M. Watanabe, G. Naco, and M. Whitman. 1997. Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature 389:85-89.
-
(1997)
Nature
, vol.389
, pp. 85-89
-
-
Chen, X.1
Weisberg, E.2
Fridmacher, V.3
Watanabe, M.4
Naco, G.5
Whitman, M.6
-
6
-
-
0031984072
-
Trojan peptides: The penetratin system for intracellular delivery
-
Derossi, D., G. Chassaing, and A. Prochiantz. 1998. Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol. 8:84-87.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 84-87
-
-
Derossi, D.1
Chassaing, G.2
Prochiantz, A.3
-
7
-
-
0033625428
-
Endogenous patterns of TGFβ superfamily signaling during early Xenopus development
-
Faure, S., M. A. Lee, T. Keller, P. ten Dijke, and M. Whitman. 2000. Endogenous patterns of TGFβ superfamily signaling during early Xenopus development. Development 127:2917-2931.
-
(2000)
Development
, vol.127
, pp. 2917-2931
-
-
Faure, S.1
Lee, M.A.2
Keller, T.3
Ten Dijke, P.4
Whitman, M.5
-
8
-
-
0027332995
-
Cloning of a TGF β type 1 receptor that forms a heteromerie complex with the TGF β type II receptor
-
Franzen, P., P. ten Dijke, H. Ichijo, H. Yamashita, P. Schulz, C. H. Heldin, and K. Miyazono. 1993. Cloning of a TGF β type 1 receptor that forms a heteromerie complex with the TGF β type II receptor. Cell 75:681-692.
-
(1993)
Cell
, vol.75
, pp. 681-692
-
-
Franzen, P.1
Ten Dijke, P.2
Ichijo, H.3
Yamashita, H.4
Schulz, P.5
Heldin, C.H.6
Miyazono, K.7
-
9
-
-
0034007925
-
Homeodomain and winged-helix transcription factors recruit activated Smads to distinet promoter elements via a common Smad interaction motif
-
Germain, S., M. Howell, G. M. Esslemont, and C. S. Hill. 2000. Homeodomain and winged-helix transcription factors recruit activated Smads to distinet promoter elements via a common Smad interaction motif. Genes Dev. 14:435-451.
-
(2000)
Genes Dev.
, vol.14
, pp. 435-451
-
-
Germain, S.1
Howell, M.2
Esslemont, G.M.3
Hill, C.S.4
-
10
-
-
0030825516
-
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4
-
Hata, A., R. S. Lo, D. Wotton, G. Lagna, and J. Massagué. 1997. Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Nature 388:82-87.
-
(1997)
Nature
, vol.388
, pp. 82-87
-
-
Hata, A.1
Lo, R.S.2
Wotton, D.3
Lagna, G.4
Massagué, J.5
-
11
-
-
0033607183
-
Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis
-
Heyer, J., D. Escalante-Alcalde, M. Lia, E. Boettinger, W. Edelmann, C. L. Stewart, and R. Kucherlapati. 1999. Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis. Proc. Natl. Acad. Sci. USA 96:12595-12600.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12595-12600
-
-
Heyer, J.1
Escalante-Alcalde, D.2
Lia, M.3
Boettinger, E.4
Edelmann, W.5
Stewart, C.L.6
Kucherlapati, R.7
-
12
-
-
0035480050
-
TGF-β signalling in early Xenopus development
-
Hill, C. S. 2001. TGF-β signalling in early Xenopus development. Curr. Opin. Genet. Dev. 11:533-540.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 533-540
-
-
Hill, C.S.1
-
13
-
-
0036336906
-
A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 in regulating gastrulation movements
-
Howell, M., G. J. Imman, and C. S. Hill. 2002. A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 in regulating gastrulation movements. Development 129:2823-2834.
-
(2002)
Development
, vol.129
, pp. 2823-2834
-
-
Howell, M.1
Imman, G.J.2
Hill, C.S.3
-
14
-
-
0034978223
-
Xenopus Smad3 is specifically expressed in the chordoneural hinge, notochord and in the endocardium of the developing heart
-
Howell, M., T. J. Mohun, and C. S. Hill. 2001. Xenopus Smad3 is specifically expressed in the chordoneural hinge, notochord and in the endocardium of the developing heart. Mech. Dev. 104:147-150.
-
(2001)
Mech. Dev.
, vol.104
, pp. 147-150
-
-
Howell, M.1
Mohun, T.J.2
Hill, C.S.3
-
16
-
-
0037185010
-
Stoichiometry of active Smad-transcription factor complexes on DNA
-
Inman, G. J., and C. S. Hill. 2002. Stoichiometry of active Smad-transcription factor complexes on DNA. J. Biol. Chem. 277:51008-51016.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 51008-51016
-
-
Inman, G.J.1
Hill, C.S.2
-
17
-
-
0029881007
-
MOLMOL: A program for display and analysis of macromolecular structures
-
Koradi, R., M. Billeter, and K. Wüthrich. 1996. MOLMOL: a program for display and analysis of macromolecular structures. J. Mol. Graph. 14:51-55.
-
(1996)
J. Mol. Graph.
, vol.14
, pp. 51-55
-
-
Koradi, R.1
Billeter, M.2
Wüthrich, K.3
-
18
-
-
0033106484
-
A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras
-
Kretzschmar, M., J. Doody, I. Timokhina, and J. Massagué. 1999. A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras. Genes Dev. 13:804-816.
-
(1999)
Genes Dev.
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massagué, J.4
-
19
-
-
0032110463
-
Smad2 and Smad3 positively and negatively regulate TGF β-dependent transcription through the forkhead DNA-binding protein FAST2
-
Labbé, E., C. Silvestri, P. A. Hoodless, J. L. Wrana, and L. Attisano. 1998. Smad2 and Smad3 positively and negatively regulate TGF β-dependent transcription through the forkhead DNA-binding protein FAST2. Mol. Cell 2:109-120.
-
(1998)
Mol. Cell
, vol.2
, pp. 109-120
-
-
Labbé, E.1
Silvestri, C.2
Hoodless, P.A.3
Wrana, J.L.4
Attisano, L.5
-
20
-
-
0032909167
-
FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor β signals
-
Liu, B., C. L. Dou, L. Prahhu, and E. Lai. 1999. FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor β signals. Mol. Cell. Biol. 19:424-430.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 424-430
-
-
Liu, B.1
Dou, C.L.2
Prahhu, L.3
Lai, E.4
-
21
-
-
0032481351
-
The L3 loop: A structural motif determining specific interactions between SMAD proteins and TGF-β receptors
-
Lo, R. S., Y. G. Chen, Y. Shi, N. P. Pavletich, and J. Massagué. 1998. The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-β receptors. EMBO J. 17:996-1005.
-
(1998)
EMBO J.
, vol.17
, pp. 996-1005
-
-
Lo, R.S.1
Chen, Y.G.2
Shi, Y.3
Pavletich, N.P.4
Massagué, J.5
-
22
-
-
11644261806
-
Automated Docking Using a Lamarckian Genetic Algorithm and an Empirical Binding Free Energy Function
-
Morris, G. M., D. S. Goodsell, R. S. Halliday, R. Huey, W. E. Hart, R. K. Belew, and A. J. Olson. 1998. Automated Docking Using a Lamarckian Genetic Algorithm and an Empirical Binding Free Energy Function. J. Computational Chem. 19:1639-1662.
-
(1998)
J. Computational Chem.
, vol.19
, pp. 1639-1662
-
-
Morris, G.M.1
Goodsell, D.S.2
Halliday, R.S.3
Huey, R.4
Hart, W.E.5
Belew, R.K.6
Olson, A.J.7
-
24
-
-
0033615702
-
Smad3 inhibits transforming growth factor-β and activin signaling by competing with Smad4 for FAST-2 binding
-
Nagarajan, R. P., J. Liu, and Y. Chen. 1999. Smad3 inhibits transforming growth factor-β and activin signaling by competing with Smad4 for FAST-2 binding. J. Biol. Chem. 274:31229-31235.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31229-31235
-
-
Nagarajan, R.P.1
Liu, J.2
Chen, Y.3
-
25
-
-
0038548187
-
Attenuation of the TGF-β-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-β-induced growth arrest
-
Nicolás, F. J., and C. S. Hill. 2003. Attenuation of the TGF-β-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-β-induced growth arrest. Oncogene 22:3698-3711.
-
(2003)
Oncogene
, vol.22
, pp. 3698-3711
-
-
Nicolás, F.J.1
Hill, C.S.2
-
26
-
-
0036638778
-
The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo
-
Norris, D. P., J. Brennan, E. K. Bikoff, and E. J. Rohertson. 2002. The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development. 129:3455-3468.
-
(2002)
Development
, vol.129
, pp. 3455-3468
-
-
Norris, D.P.1
Brennan, J.2
Bikoff, E.K.3
Rohertson, E.J.4
-
27
-
-
0035827581
-
Functional characterization of transforming growth factor β signaling in Smad2- and Smad3-deficient fibroblasts
-
Piek, E., W. J. Ju, J. Heyer, D. Escalante-Alcalde, C. L. Stewart, M. Weinstein, C. Deng, R. Kucherlapati, E. P. Bottinger, and A. B. Roherts. 2001. Functional characterization of transforming growth factor β signaling in Smad2- and Smad3-deficient fibroblasts. J. Biol. Chem. 276:19945-19953.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19945-19953
-
-
Piek, E.1
Ju, W.J.2
Heyer, J.3
Escalante-Alcalde, D.4
Stewart, C.L.5
Weinstein, M.6
Deng, C.7
Kucherlapati, R.8
Bottinger, E.P.9
Roherts, A.B.10
-
28
-
-
0034460336
-
Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus
-
Pierreux, C. E., F. J. Nicolás, and C. S. Hill. 2000. Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus. Mol. Cell. Biol. 20:9041-9054.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9041-9054
-
-
Pierreux, C.E.1
Nicolás, F.J.2
Hill, C.S.3
-
29
-
-
0034618568
-
The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of nodal signaling required for organizer formation
-
Pogoda, H., L. Solnica-Krezel, W. Driever, and D. Meyer. 2000. The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of nodal signaling required for organizer formation. Curr. Biol. 10:1041-1049.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1041-1049
-
-
Pogoda, H.1
Solnica-Krezel, L.2
Driever, W.3
Meyer, D.4
-
30
-
-
0033573092
-
Crystal structure of a transcriptionally active Smad4 fragment
-
Qin, B., S. S. Lam, and K. Lin. 1999. Crystal structure of a transcriptionally active Smad4 fragment. Structure Fold Des. 7:1493-1503.
-
(1999)
Structure Fold Des.
, vol.7
, pp. 1493-1503
-
-
Qin, B.1
Lam, S.S.2
Lin, K.3
-
31
-
-
0036682952
-
Smad3 allostery links TGF-β receptor kinase activation to transcriptional control
-
Qin, B. Y., S. S. Lam, J. J. Correia, and K. Lim. 2002. Smad3 allostery links TGF-β receptor kinase activation to transcriptional control. Genes Dev. 16:1950-1963.
-
(2002)
Genes Dev.
, vol.16
, pp. 1950-1963
-
-
Qin, B.Y.1
Lam, S.S.2
Correia, J.J.3
Lim, K.4
-
32
-
-
0037080983
-
Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif
-
Randall, R. A., S. Germain, G. J. Inman, P. A. Bates, and C. S. Hill. 2002. Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif. EMBO J. 21:145-156.
-
(2002)
EMBO J.
, vol.21
, pp. 145-156
-
-
Randall, R.A.1
Germain, S.2
Inman, G.J.3
Bates, P.A.4
Hill, C.S.5
-
33
-
-
0030837455
-
A structural basis for mutational inactivation by the tumour suppressor Smad4
-
Shi, Y., A. Hata, R. S. Lo, J. Massagué, and N. P. Pavletich. 1997. A structural basis for mutational inactivation by the tumour suppressor Smad4. Nature 388:87-93.
-
(1997)
Nature
, vol.388
, pp. 87-93
-
-
Shi, Y.1
Hata, A.2
Lo, R.S.3
Massagué, J.4
Pavletich, N.P.5
-
34
-
-
17744364498
-
Two-step regulation of left-right asymmetric expression of Pitx2: Initiation by nodal signaling and maintenance by Nkx2
-
Shiratori, H., R. Sakuma, M. Watanabe, H. Hashiguchi, K. Mochida, Y. Sakai, J. Nishino, Y. Saijoh, M. Whitman, and H. Hamada. 2001. Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2. Mol. Cell 7:137-149.
-
(2001)
Mol. Cell
, vol.7
, pp. 137-149
-
-
Shiratori, H.1
Sakuma, R.2
Watanabe, M.3
Hashiguchi, H.4
Mochida, K.5
Sakai, Y.6
Nishino, J.7
Saijoh, Y.8
Whitman, M.9
Hamada, H.10
-
35
-
-
0034618657
-
Fast1 is required for the development of dorsal axial structures in zebrafish
-
Sirotkin, H. I., M. A. Gates, P. D. Kelly, A. F. Schier, and W. S. Talbot. 2000. fast1 is required for the development of dorsal axial structures in zebrafish. Curr. Biol. 10:1051-1054.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1051-1054
-
-
Sirotkin, H.I.1
Gates, M.A.2
Kelly, P.D.3
Schier, A.F.4
Talbot, W.S.5
-
36
-
-
0033854950
-
Formation of the definitive endoderm in mouse is a Smad2-dependent process
-
Tremblay, K. D., P. A. Hoodless, E. K. Bikoff, and E. J. Robertson. 2000. Formation of the definitive endoderm in mouse is a Smad2-dependent process. Development 127:3079-3090.
-
(2000)
Development
, vol.127
, pp. 3079-3090
-
-
Tremblay, K.D.1
Hoodless, P.A.2
Bikoff, E.K.3
Robertson, E.J.4
-
38
-
-
0032414597
-
A mouse homologue of FAST-1 transduces TGFβ superfamily signals and is expressed during early embryogenesis
-
Weisberg, E., G. E. Winnier, X. Chen, C. L. Farnsworth, B. L. Hogan, and M. Whitman. 1998. A mouse homologue of FAST-1 transduces TGFβ superfamily signals and is expressed during early embryogenesis. Mech. Dev. 79:17-27.
-
(1998)
Mech. Dev.
, vol.79
, pp. 17-27
-
-
Weisberg, E.1
Winnier, G.E.2
Chen, X.3
Farnsworth, C.L.4
Hogan, B.L.5
Whitman, M.6
-
39
-
-
0026496172
-
TGFβ signals through a heteromeric protein kinase receptor complex
-
Wrana, J. L., L. Attisano, J. Cárcamo, A. Zentella, J. Doody, M. Laiho, X. F. Wang, and J. Massagué. 1992. TGFβ signals through a heteromeric protein kinase receptor complex. Cell 71:1003-1014.
-
(1992)
Cell
, vol.71
, pp. 1003-1014
-
-
Wrana, J.L.1
Attisano, L.2
Cárcamo, J.3
Zentella, A.4
Doody, J.5
Laiho, M.6
Wang, X.F.7
Massagué, J.8
-
40
-
-
0034614708
-
Structural basis of Smd2 recognition by the Smad anchor for receptor activation
-
Wu, G., Y. G. Chen, B. Ozdamar, C. A. Gyuricza, P. A. Chong, J. L. Wrana, J. Massagué, and Y. Shi. 2000. Structural basis of Smd2 recognition by the Smad anchor for receptor activation. Science 287:92-97.
-
(2000)
Science
, vol.287
, pp. 92-97
-
-
Wu, G.1
Chen, Y.G.2
Ozdamar, B.3
Gyuricza, C.A.4
Chong, P.A.5
Wrana, J.L.6
Massagué, J.7
Shi, Y.8
-
41
-
-
0035827668
-
Formation of a Stable Heterodimer between Smad2 and Smad4
-
Wu, J. W., R. Fairman, J. Penry, and Y. Shi. 2001. Formation of a Stable Heterodimer between Smad2 and Smad4. J. Biol. Chem. 276:20688-20694.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20688-20694
-
-
Wu, J.W.1
Fairman, R.2
Penry, J.3
Shi, Y.4
-
42
-
-
18244362844
-
Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-β signaling
-
Wu, J. W., M. Hu, J. Chai, J. Scoane, M. Huse, C. Li, D. J. Rigotti, S. Kyin, T. W. Muir, R. Fairman, J. Massagué, and Y. Shi. 2001. Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-β signaling. Mol. Cell 8:1277-1289.
-
(2001)
Mol. Cell
, vol.8
, pp. 1277-1289
-
-
Wu, J.W.1
Hu, M.2
Chai, J.3
Scoane, J.4
Huse, M.5
Li, C.6
Rigotti, D.J.7
Kyin, S.8
Muir, T.W.9
Fairman, R.10
Massagué, J.11
Shi, Y.12
-
43
-
-
0036670359
-
Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFβ signaling complexes in the cytoplasm and nucleus
-
Xu, L., Y. Kang, S. Col, and J. Massagué. 2002. Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFβ signaling complexes in the cytoplasm and nucleus. Mol. Cell 10:271-282.
-
(2002)
Mol. Cell
, vol.10
, pp. 271-282
-
-
Xu, L.1
Kang, Y.2
Col, S.3
Massagué, J.4
-
44
-
-
0033534573
-
Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3
-
Yagi, K., D. Goto, T. Hamamoto, S. Takenoshita, M. Kato, and K. Miyazono. 1999. Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3. J. Biol. Chem. 274:703-709.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 703-709
-
-
Yagi, K.1
Goto, D.2
Hamamoto, T.3
Takenoshita, S.4
Kato, M.5
Miyazono, K.6
-
45
-
-
0033543741
-
The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis
-
Yeo, C. Y., X. Chen, and M. Whitman. 1999. The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis. J. Biol. Chem. 274:26584-26590.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26584-26590
-
-
Yeo, C.Y.1
Chen, X.2
Whitman, M.3
-
46
-
-
0032110707
-
Characterization of human FAST-1, a TGF β and activin signal transducer
-
Zhou, S., L. Zawel, C. Lengauer, K. W. Kinzler, and B. Vogelstein. 1998. Characterization of human FAST-1, a TGF β and activin signal transducer. Mol. Cell 2:121-127.
-
(1998)
Mol. Cell
, vol.2
, pp. 121-127
-
-
Zhou, S.1
Zawel, L.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
|