Pediatric Patients with Untreated Ulcerative Colitis May Present Initially with Unusual Morphologic Findings

American Journal of Surgical Pathology

Volumn 28, Issue 2, 2004, Pages 190-197

  Glickman, Jonathan N ^a,c   Bousvaros, Athos ^b   Farraye, Francis A ^d   Zholudev, Anna ^b   Friedman, Sonia ^c   Wang, Helen H ^a   Leichtner, Alan M ^b   Odze, Robert D ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Biopsy; Children; Ulcerative colitis

Indexed keywords

ADOLESCENT; ADULT; AGE; ARTICLE; CHILD; CHRONIC DISEASE; COLON BIOPSY; COLON MUCOSA; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; ENTERITIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; METAPLASIA; MORPHOLOGY; PANETH CELL; PLASMACYTOSIS; RECTUM BIOPSY; RECTUM MUCOSA; RISK FACTOR; SYMPTOMATOLOGY; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; COLITIS, ULCERATIVE; COLON; ENDOSCOPY, DIGESTIVE SYSTEM; FEMALE; HUMANS; MALE; MIDDLE AGED; RECTUM; RETROSPECTIVE STUDIES;

EID: 1642453629     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200402000-00006     Document Type: Article

References (15)

1. d'Haens G, Geboes K, Ponette E, et al. Patchy cecal inflammation associated with distal ulcerative colitis: a prospective endoscopic study. Am J Gastroenterol. 1997;92:1275-1279.
2. Goldman H. Ulcerative colitis and Crohn's disease. In: Ming S-C, Goldman H, eds. Pathology of the Gastrointestinal Tract. Baltimore: Williams & Wilkins, 1998:673-717.
3. Groisman GM, George J, Harpaz N. Ulcerative appendicitis in universal and nonuniversal ulcerative colitis. Mod Pathol. 1994;7:322-325.
4. Kleer CG, Appelman H. Ulcerative colitis: patterns of involvement in colorectal biopsies and changes with time. Am J Surg Pathol. 1998;22:983-989.
5. Kroft SH, Stryker SJ, Rao MS. Appendiceal involvement as a skip lesion in ulcerative colitis. Mod Pathol. 1994;7:912-914.
6. Langholz E, Munkholm P, Krasnilikoff PA, et al. Inflammatory bowel diseases with onset in childhood: clinical features, morbidity, and mortality in a regional cohort. Scand J Gastroenterol. 1997;32:139-147.
7. Mamula P, Telega GW, Markowitz JE, et al. Inflammatory bowel disease in children 5 years of age and younger. Am J Gastroenterol. 2002;97:2005-2010.
8. Markowitz J, Kahn E, Grandcher K, et al. Atypical rectosigmoid histology in children with newly diagnosed ulcerative colitis. Am J Gastroenterol. 1993;88:2034-2037.
9. Nostrant TT, Kumar NB, Appelman HD. Histopathology differentiates acute self-limited colitis from ulcerative colitis. Gastroenterology. 1987;92:318-328.
10. Odze R, Antonioli D, Peppercorn M, et al. Effect of topical 5-aminosalicylic acid (5-ASA) therapy on rectal mucosal biopsy morphology in chronic ulcerative colitis. Am J Surg Pathol. 1993;17:869-875.
11. Odze RD, Wershil BK, Leichtner AM, et al. Allergic colitis in infants. J Pediatr. 1995;126:163-170.
12. Okawa K, Aoki T, Sano K, et al. Ulcerative colitis with skip lesions at the mouth of the appendix: a clinical study. Am J Gastroenterol. 1998;93:2405-2410.
13. Surawicz C, Haggitt R, Husseman M, et al. Mucosal biopsy diagnosis of colitis: acute self-limited colitis and inflammatory bowel disease. Gastroenterology. 1994;107:755-763.
14. Tanaka M, Riddell RH, Saito H, et al. Morphologic criteria applicable to biopsy specimens for effective distinction of inflammatory bowel disease from other forms of colitis and of Crohn's disease from ulcerative colitis. Scand J Gastroenterol. 1999;34:55-67.
15. Washington K, Greenson JK, Montgomery E, et al. Histopathology of ulcerative colitis in initial rectal biopsy in children. Am J Surg Pathol. 2002;26:1441-1449.